Mytrex (Topical)

Nystatin and triamcinolone combination has an antifungal and a corticosteroid (cortisone-like medicine).

Antifungals treat infections caused by a fungus. They work by killing the fungus or stopping it from growing. This medicine will not work for other types of infections. Corticosteroids are part of a group of medicines called steroids. They help reduce redness, swelling, itching, and other discomfort related to many skin issues.

This medicine is used to treat certain fungal infections, such as Candida (Monilia), and to help relieve discomfort from the infection.

Topical corticosteroids may rarely cause serious side effects. Some side effects may be more likely in children. Before using this medicine in children, talk to your doctor about these risks, as well as the benefits this medicine may provide.

Nystatin and triamcinolone combination is available only with your doctor's prescription.

To fully clear up your infection and help prevent it from coming back, it’s important to follow good health habits. Keep the affected area as cool and dry as you can.

If your skin issue does not improve within 2 or 3 weeks, or if it gets worse, contact your doctor.

The corticosteroid in this medicine can be absorbed through the skin and may have a higher chance of causing side effects in children. Long-term use may also impact growth and development. Children who need to use this medicine should be closely monitored by their doctor.

For diabetic patients:

• Although it is rare, the corticosteroid in this medicine may raise blood and urine sugar levels, especially if you have severe diabetes and are using large amounts of this medicine. Talk to your doctor before changing your diet or the dosage of your diabetes medicine.

In deciding to use a medicine, you and your doctor need to consider the risks and benefits. For this medicine, keep the following in mind:

Allergies

Inform your doctor if you have ever had any unusual or allergic reactions to this medicine or any other medicines. Also, let your healthcare professional know about any other types of allergies, such as those to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Children may be more sensitive to the effects of topical nystatin and triamcinolone combination, which may increase the chances of side effects during treatment. Therefore, it is very important to talk with your child's doctor about the benefits and risks of this medicine.

Geriatric

Many medicines have not been specifically studied in older adults. So, it may not be clear if they work the same way as they do in younger adults. While there is no specific information comparing the use of topical nystatin and triamcinolone combination in older adults to other age groups, it is not expected to cause different side effects or problems in older people than in younger adults.

Breast Feeding

There are no sufficient studies in women to determine the risk to infants when using this medication during breastfeeding. Consider the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Certain medicines should not be used together at all, while in some cases, two different medicines may be used together even if there is a chance of interaction. In these situations, your doctor may adjust the dose or take other precautions. It is especially important that your healthcare professional knows if you are taking any of the following medicines when using this medicine. The following interactions are highlighted for their potential significance but are not necessarily a complete list.

Using this medicine with any of the following medicines is not recommended. Your doctor may choose not to treat you with this medication or change some of your other medicines.

• Desmopressin
• Rotavirus Vaccine, Live

Using this medicine with any of the following medicines is usually not recommended, but may be necessary in some cases. If both medicines are prescribed together, your doctor may adjust the dose or frequency of one or both medicines.

• Aldesleukin
• Aspirin
• Atazanavir
• Balofloxacin
• Bemiparin
• Besifloxacin
• Ceritinib
• Ciprofloxacin
• Cobicistat
• Darunavir
• Enoxacin
• Fleroxacin
• Flumequine
• Gatifloxacin
• Gemifloxacin
• Levofloxacin
• Lomefloxacin
• Lutetium Lu 177 Dotatate
• Macimorelin
• Moxifloxacin
• Nadifloxacin
• Nadroparin
• Nirmatrelvir
• Norfloxacin
• Ofloxacin
• Pazufloxacin
• Pefloxacin
• Prulifloxacin
• Ritonavir
• Rufloxacin
• Sargramostim
• Somatrogon-ghla
• Sparfloxacin
• Tosufloxacin

Using this medicine with any of the following medicines may increase the risk of certain side effects, but using both medicines may be the best treatment for you. If both medicines are prescribed together, your doctor may adjust the dose or frequency of one or both medicines.

• Alcuronium
• Atracurium
• Auranofin
• Fosphenytoin
• Gallamine
• Hexafluorenium
• Licorice
• Metocurine
• Phenytoin
• Primidone
• Saiboku-To

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used around the time of eating food or certain types of food due to possible interactions. Using alcohol or tobacco with some medicines may also cause interactions. Discuss with your healthcare professional about using your medicine with food, alcohol, or tobacco.

Other Medical Problems

Other medical problems may affect the use of this medicine. Make sure to inform your doctor if you have any other medical issues, especially:

• Herpes
• Vaccinia (cowpox)
• Varicella (chickenpox)
• Other virus infections of the skin—Triamcinolone may speed up the spread of virus infections
• Tuberculosis (TB) of the skin—Triamcinolone may worsen a TB infection

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

• Blistering, burning, dryness, itching, peeling, or other signs of irritation not present before use of this medicine

Check with your doctor as soon as possible if any of the following side effects occur:

Many of the above side effects are more likely to occur in children, who may absorb greater amounts of this medicine.

• Acne or oily skin
• Increased hair growth, especially on the face
• Increased loss of hair, especially on the scalp
• Reddish purple lines on arms, face, legs, trunk, or groin
• Thinning of skin with easy bruising

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Mycolog-II
• Mytrex
• Quenalog

Available Dosage Forms:

• Cream
• Ointment

Therapeutic Class: Anti-Infective/Anti-Inflammatory Combination

Pharmacologic Class: Triamcinolone

Chemical Class: Polyene

Do not use this medicine in or around the eyes.

Check with your doctor before using this medicine on any other skin problems. It should not be used on bacterial or virus infections. Also, it should only be used on certain fungus infections of the skin.

Apply a thin layer of this medicine to the affected area and rub in gently and thoroughly.

The use of any kind of airtight covering over this medicine may increase absorption of the medicine and the chance of irritation and other side effects. Therefore, do not bandage, wrap, or apply any airtight covering or other occlusive dressing (for example, kitchen plastic wrap) over this medicine unless directed to do so by your doctor. Also, wear loose-fitting clothing when using this medicine on the groin area. When using this medicine on the diaper area of children, avoid tight-fitting diapers and plastic pants.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if your symptoms have disappeared. Do not miss any doses. However, do not use this medicine more often or for a longer time than your doctor ordered. To do so may increase absorption through your skin and the chance of side effects. In addition, too much use, especially on thin skin areas (for example, face, armpits, groin), may result in thinning of the skin and stretch marks.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For fungus infections: For cream dosage form: Adults and children—Apply to the affected area(s) of the skin two times a day, morning and evening For ointment dosage form: Adults and children—Apply to the affected area(s) of the skin two or three times a day.

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

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