Naratriptan

Naratriptan is a headache medicine that narrows blood vessels around the brain. Naratriptan also reduces substances in the body that can trigger headache pain, sensitivity to light and sound, and other migraine symptoms.

Naratriptan is used to treat migraine headaches. Naratriptan will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.

Naratriptan should not be used to treat a common tension headache, a headache that causes loss of movement on one side of your body, or any headache that seems to be different from your usual migraine headaches. Use naratriptan only if your condition has been confirmed by a doctor as migraine headaches.

Naratriptan may also be used for purposes not listed in this medication guide.

Your doctor may want to give your first dose of naratriptan in a hospital or clinic setting to quickly treat any serious side effects that occur.

Follow all directions on your prescription label. Never use more than your recommended dose. Overuse of migraine headache medicine can make headaches worse. Tell your doctor if the medicine seems to stop working as well in treating your migraine attacks.

Take naratriptan as soon as you notice migraine symptoms.

Take 1 tablet whole with a full glass of water.

After taking a tablet: If your headache does not go away completely, or if it goes away and comes back, call your doctor before taking a second tablet.

Do not take the second tablet until at least 4 hours have passed since you took the first tablet. Do not take more than 5 milligrams (mg) of naratriptan in 24 hours.

If your symptoms have not improved after taking 2 tablets in 24 hours, contact your doctor before taking any more tablets.

Tell your doctor if you have more than four headaches in one month (30 days).

Naratriptan can raise blood pressure to dangerous levels. Your blood pressure may need to be checked often while you are using this medicine. If you use naratriptan long-term, your heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG).

Store at room temperature away from moisture, heat, and light.

You should not use naratriptan if you have uncontrolled high blood pressure, heart problems, certain heart rhythm disorders, severe liver or kidney disease, a history of heart attack or stroke, or circulation problems that cause a lack of blood supply within the body.

Do not take naratriptan within 24 hours before or after using another migraine headache medicine.

You should not use this medicine if you are allergic to naratriptan, or if you have:

• severe or uncontrolled high blood pressure;
• past or present heart problems;
• history of coronary artery disease, heart attack, or stroke, including "mini-stroke";
• Wolff-Parkinson-White syndrome or other heart rhythm disorder;
• a blood vessel disorder or circulation problems that cause a lack of blood supply within the body;
• severe liver or kidney disease; or
• a headache that seems different from your usual migraine headaches.

To make sure naratriptan is safe for you, tell your doctor if you have:

• liver or kidney disease;
• high blood pressure, a heart rhythm disorder; or
• coronary heart disease (or risk factors such as diabetes, menopause, smoking, being overweight, having high cholesterol, having a family history of coronary artery disease, being older than 40 and a man, or being a woman who has had a hysterectomy).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether naratriptan passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

Do not give this medicine to anyone younger than 18.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Naratriptan may cause serious side effects. Stop using naratriptan and call your doctor right away if you have:

• fast or pounding heartbeats;
• numbness or tingling, and a pale or blue color in your fingers or toes;
• pain or a heavy feeling in your legs, hip pain, burning pain in your feet;
• sudden and severe stomach pain, bloody diarrhea, constipation, fever, weight loss;
• dangerously high blood pressure—severe headache, blurred vision, pounding in your neck or ears, nosebleed, anxiety, confusion, severe chest pain, shortness of breath, irregular heartbeats, seizure;
• heart attack symptoms—chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
• high levels of serotonin in the body—agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting; or
• signs of a stroke—sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance.

Common side effects of naratriptan may include:

• dizziness, drowsiness;
• feeling weak or tired;
• numbness or tingling;
• flushing (warmth, redness, or tingling);
• nausea; or
• pain or tightness in your jaw, neck, or throat.

This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Usual Adult Dose for Migraine:

Use only after a clear diagnosis of migraine has been establishedInitial dose: 1 mg or 2.5 mg orally, once-Provided there has been some response to first dose, a second dose may be administered at least 4 hours later if migraine returns or symptoms recur.Maximum dose: 5 mg in a 24-hour period Comments:-This drug should not be used to treat basilar or hemiplegic migraines because these patients are at a greater risk of stroke.-The safety of treating an average of 4 or more migraine attacks in a 30-day period has not been established. Use: For the acute treatment of migraine with or without aura.

Since naratriptan is used as needed, there is no daily dosing schedule. Call your doctor if your symptoms do not improve after using naratriptan.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include tiredness, neck stiffness, loss of coordination, or feeling light-headed.

Do not take naratriptan within 24 hours before or after using another migraine headache medicine, including:

• medicines like naratriptan--almotriptan, eletriptan, frovatriptan, rizatriptan, sumatriptan, zolmitriptan, and others; or
• ergot medicine--dihydroergotamine, ergotamine, ergonovine, methylergonovine.

naratriptan may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Taking naratriptan with certain other medicines can lead to a dangerous increase in serotonin in your body, a condition known as "serotonin syndrome," which can be life-threatening. Let your doctor know if you are also using:

• medicine for depression;
• medicine for a psychiatric disorder;
• a narcotic (opioid) medication; or
• medicine to stop nausea and vomiting.

This list is not complete. Other drugs may interact with naratriptan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are included in this medication guide.