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Natrol Melatonin + 5-HTP

Generic name: 5-hydroxytryptophan, melatonin, and pyridoxine

Brand names: Natrol Melatonin + 5-HTP

Last updated November 3, 2026 0 views
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What is Natrol Melatonin + 5-HTP?

Natrol Melatonin + 5-HTP is likely effective in alternative medicine to help you relax, fall asleep, and stay asleep.

It is not certain whether Natrol Melatonin + 5-HTP is effective for treating any medical condition. The medicinal use of this product has not been approved by the FDA. This medicine should not be used instead of medication prescribed by your doctor.

Natrol Melatonin + 5-HTP is often sold as an herbal supplement. There are no regulated manufacturing standards for many herbal compounds, and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to reduce the risk of contamination.

Natrol Melatonin + 5-HTP may also be used for purposes not listed in this product guide.

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How should I take Natrol Melatonin + 5-HTP?

When thinking about using 5-hydroxytryptophan, melatonin, and pyridoxine, talk to your doctor. You might also want to consult a practitioner who knows about herbal or health supplements.

If you decide to use Natrol Melatonin + 5-HTP, follow the instructions on the package or those given by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than what is recommended on the label.

Natrol Melatonin + 5-HTP is taken once a day, 20 minutes before bedtime.

Swallow the tablet whole and do not crush, chew, or break it.

Store at room temperature away from moisture and heat.

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Warnings

Follow all instructions on the product label and package. Inform each of your healthcare providers about all your medical conditions, allergies, and all medicines you are using.

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Before taking this medicine

Before using Natrol Melatonin + 5-HTP, speak with your healthcare provider. You may not be able to use this product if you have certain medical conditions, especially:

  • depression;
  • migraines;
  • Parkinson's disease; or
  • mental illness or psychosis.

Ask a doctor, pharmacist, or other healthcare provider if it is safe for you to use this product if you have or have ever had:

  • an autoimmune disorder; or
  • a depressive disorder.

Do not use Natrol Melatonin + 5-HTP if you are pregnant or breastfeeding.

Do not give any herbal/health supplement to a child without medical advice.

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Natrol Melatonin + 5-HTP side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.

While not all side effects are known, Natrol Melatonin + 5-HTP is believed to be possibly safe when taken for a short time.

Common side effects of Natrol Melatonin + 5-HTP may include:

  • headache;
  • stomach discomfort; or
  • daytime drowsiness or a "hangover" feeling.

This is not a complete list of side effects and others may happen. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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What happens if I miss a dose?

Natrol Melatonin + 5-HTP is taken as needed. If you miss a dose while on a schedule, just skip it. Do not take two doses at once.

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What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

This product may cause drowsiness or sleepiness and may impair your reactions. Avoid driving or doing anything dangerous until you know how Natrol Melatonin + 5-HTP will affect you.

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What other drugs will affect Natrol Melatonin + 5-HTP?

Do not take this product with any herbal or health supplement that has L-Tryptophan or 5-hydroxytryptophan.

Other drugs may impact how Natrol Melatonin + 5-HTP works, including prescription and over-the-counter medicines, vitamins, and herbal products. Inform your doctor about all other medicines you are using.

This section was rewritten for readability and reviewed for meaning.

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.