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Aminoglycosides oral tablet (500 mg)

Neomycin

Generic name: neomycin

Brand names: Mycifradin, Neo-Fradin, Neo-Tab

Last updated November 3, 2026 0 views
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What is neomycin?

Neomycin is an antibiotic that helps prevent bacterial infection in the intestines. It is also used to lessen the symptoms of hepatic coma.

Neomycin is sometimes given along with another antibiotic.

Neomycin may also be used for reasons not mentioned in this medication guide.

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How should I take neomycin?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Never take more than prescribed, or take for longer than 2 weeks. High doses or long-term use of neomycin can cause permanent hearing loss.

Keep using this medicine even if your symptoms quickly improve. Skipping doses could make your infection resistant to medication. Neomycin will not treat a viral infection (flu or a common cold).

Drink plenty of water each day to stay hydrated.

Your hearing and kidney function may need to be tested.

For hepatic coma, neomycin is usually taken for only 5 to 6 days. Avoid eating foods high in protein during this time. Follow all instructions of your doctor or dietitian about adding protein back to your diet after treatment.

Tell your doctor if you have a planned surgery.

Store tightly closed at room temperature, away from moisture and heat.

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Warnings

Neomycin can harm your kidneys or cause hearing problems. Hearing loss may be permanent if you take too much neomycin or take it for longer than recommended.

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Before taking this medicine

You should not take neomycin if you are allergic to it, or if you have:

  • ulcerative colitis, Crohn's disease, or other inflammatory bowel disease;
  • a blockage in your intestines; or
  • an allergy to similar antibiotics such as amikacin, gentamicin, kanamycin, paromomycin, streptomycin, or tobramycin.

Tell your doctor if you have ever had:

  • kidney disease;
  • myasthenia gravis; or
  • Parkinson's disease.

May harm an unborn baby. Tell your doctor if you are pregnant.

Do not breastfeed.

Do not give neomycin to a child without medical advice.

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Neomycin side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Neomycin may cause serious side effects. Call your doctor right away if you have:

  • numbness or a tingling feeling under your skin;
  • hearing problems (even long after you stop taking neomycin);
  • muscle twitching or seizures;
  • weak or shallow breathing; or
  • kidney problems—swelling, urinating less, feeling tired, or short of breath.

Common side effects of neomycin may include:

  • nausea or vomiting; or
  • diarrhea.

This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is close to the time for your next dose. Do not take two doses at the same time.

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What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Do not share neomycin with another person, even if they have the same symptoms you have.

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What other drugs will affect neomycin?

Neomycin can harm your kidneys, especially if you also take certain medicines for infections, cancer, osteoporosis, organ transplant rejection, bowel disorders, high blood pressure, or pain or arthritis (including Advil, Motrin, and Aleve).

Tell your doctor about all your other medicines, especially:

  • any other antibiotics;
  • digoxin;
  • fluorouracil;
  • methotrexate;
  • vitamin B-12;
  • a blood thinner--warfarin, Coumadin, Jantoven; or
  • a diuretic or "water pill"--furosemide or ethacrynic acid.

This list is not complete. Other drugs may affect neomycin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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Common questions about neomycin

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Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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