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Neomycin, polymyxin b, and bacitracin (Topical)

Generic name: neomycin, polymyxin b, and bacitracin

Brand names: Triple Antibiotic, Ultra Mide

Last updated September 4, 2026 0 views
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Uses for neomycin, polymyxin b, and bacitracin

Neomycin, Polymyxin B, and Bacitracin is a combination antibiotic that helps prevent skin infections.

Neomycin, polymyxin B, and bacitracin combination is available over the counter.

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Precautions while using neomycin, polymyxin b, and bacitracin

If your skin issue does not get better in 1 week, or if it gets worse, contact your health care professional.

This section was rewritten for readability and reviewed for meaning.

Before using neomycin, polymyxin b, and bacitracin

In deciding to use a medicine, it's important to consider the risks of taking it against the benefits it may provide. This is a choice you and your doctor will make together. For this medicine, please consider the following:

Allergies

Inform your doctor if you have ever had an unusual or allergic reaction to this medicine or any other medicines. Also, let your healthcare professional know about any other allergies you have, such as to foods, dyes, preservatives, or animals. For over-the-counter products, read the label or package ingredients carefully.

Pediatric

Research on this medicine has only been conducted in adult patients, and there is no specific information comparing the use of topical neomycin, polymyxin B, and bacitracin combination in children to its use in other age groups.

Geriatric

Many medicines have not been studied specifically in older adults. As a result, it may not be clear whether they work the same way in older people as they do in younger adults or if they cause different side effects or issues in older individuals. There is no specific information comparing the use of topical neomycin, polymyxin B, and bacitracin combination in elderly patients to its use in other age groups.

Breast Feeding

Studies in women indicate that this medication poses minimal risk to the infant when used during breastfeeding.

There are no adequate studies in women to assess the risk to infants when using this medication during breastfeeding. Consider the potential benefits and risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should not be used together at all, while in other cases, two different medicines may be used together even if an interaction might happen. In these situations, your doctor may adjust the dose, or other precautions may be needed. When you are taking this medicine, it is especially important that your healthcare professional knows if you are taking any of the medicines listed below. The following interactions have been chosen based on their potential significance but may not include all possible interactions.

Using this medicine with any of the following medicines is usually not recommended, but may be necessary in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you take one or both medicines.

  • Alcuronium
  • Aspirin
  • Atracurium
  • Cidofovir
  • Cisatracurium
  • Colistimethate Sodium
  • Decamethonium
  • Doxacurium
  • Emtricitabine
  • Ethacrynic Acid
  • Fazadinium
  • Foscarnet
  • Furosemide
  • Gallamine
  • Hexafluorenium
  • Metocurine
  • Mivacurium
  • Pancuronium
  • Pipecuronium
  • Rapacuronium
  • Rocuronium
  • Sorafenib
  • Tacrolimus
  • Tenofovir Alafenamide
  • Tubocurarine
  • Vecuronium

Using this medicine with any of the following medicines may increase the risk of certain side effects, but using both medications may be the best option for you. If both medicines are prescribed together, your doctor may adjust the dose or how often you take one or both medicines.

  • Bumetanide

Interactions with Food/Tobacco/Alcohol

Some medicines should not be used around the time of eating food or specific types of food due to possible interactions. Combining alcohol or tobacco with certain medicines may also lead to interactions. Talk to your healthcare professional about using your medicine with food, alcohol, or tobacco.

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Side Effects of neomycin, polymyxin b, and bacitracin

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may happen, if they do, they may need medical attention.

Check with your doctor right away if any of the following side effects occur:

More common

  • Itching, skin rash, redness, swelling, or any other sign of irritation that was not present before using this medicine

Rare

  • Any loss of hearing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

  • Triple Antibiotic
  • Ultra Mide

Available Dosage Forms:

  • Ointment

Therapeutic Class: Antibacterial Combination

Chemical Class: Aminoglycoside

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Proper use of neomycin, polymyxin b, and bacitracin

If you are using this medicine without a prescription, do not use it to treat deep wounds, puncture wounds, serious burns, or raw areas without first checking with your health care professional.

Do not use this medicine in the eyes.

Before applying this medicine, wash the affected area with soap and water, and dry thoroughly.

After applying this medicine, the treated area may be covered with a gauze dressing if desired.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if your symptoms have disappeared. Do not miss any doses.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For topical dosage form (ointment): For prevention of minor bacterial infections: Adults and children—Apply to the affected area(s) of the skin two to five times a day.

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.