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Neuac

Generic name: benzoyl peroxide and clindamycin topical

Brand names: Acanya, Neuac, Onexton, Z-Clinz 10, DUAC, Z-Clinz 5

Last updated November 3, 2026 0 views
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What is Neuac?

Benzoyl peroxide kills bacteria. It also dries the skin slightly, which helps remove extra oil and dirt.

Clindamycin is an antibiotic that stops bacteria from growing on the skin.

Neuac (for the skin) is a combination medicine used to treat acne.

Neuac may also be used for reasons not mentioned in this medication guide.

This section was rewritten for readability and reviewed for meaning.

Warnings

This medicine can cause a rare but serious allergic reaction or severe skin irritation. Stop using this medicine and get emergency medical help if you have: hives, itching; difficulty breathing, feeling light-headed; or swelling of your face, lips, tongue, or throat.

This section was rewritten for readability and reviewed for meaning.

Before taking this medicine

You should not use Neuac if you are allergic to benzoyl peroxide or clindamycin (Cleocin, Clina-Derm, Clindets).

Even though this medicine is applied to the skin, your body may absorb enough clindamycin to cause serious side effects. You may not be able to use this medicine if you have:

  • inflammation of your intestines (also called enteritis);
  • ulcerative colitis; or
  • if you have ever had severe diarrhea caused by antibiotic medicine.

It is not known whether Neuac will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether benzoyl peroxide and clindamycin topical passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

This section was rewritten for readability and reviewed for meaning.

Neuac side effects

Benzoyl peroxide can cause a rare but serious allergic reaction or severe skin irritation. These reactions may happen just a few minutes after you apply the medicine, or within a day or longer afterward.

Stop using Neuac and get emergency medical help if you notice signs of an allergic reaction: hives, itching; difficulty breathing, feeling light-headed; swelling of your face, lips, tongue, or throat.

This medicine may cause serious side effects. Stop using this medicine and call your doctor immediately if you experience:

  • severe redness, burning, stinging, or peeling of treated skin areas; or
  • diarrhea that is watery or bloody.

Common side effects of Neuac may include:

  • mild burning or stinging;
  • itching or tingling feeling;
  • dryness or peeling of treated skin; or
  • redness or other irritation.

This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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How should I use Neuac?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Using more medicine or applying it more often than prescribed will not make it work any faster, and may increase side effects.

Benzoyl peroxide can cause a rare but serious allergic reaction or severe skin irritation. Before you start using this medicine, you may choose to apply a "test dose" to see if you have a reaction. Apply a very small amount of the medicine to 1 or 2 small acne areas every day for 3 days in a row. If there is no reaction, begin using the full prescribed amount on the 4th day.

Wash your hands before and after applying this medicine.

Wash your face with a mild cleanser (not soap) and pat the skin dry with a clean towel.

Neuac is usually applied twice daily, in the morning and evening.

Avoid getting this medicine in your eyes, mouth, or nose (or in the creases of your nose), or on your lips. If it does get into any of these areas, wash with water. Do not apply this medicine to sunburned, windburned, dry, chapped, irritated, or broken skin.

It may take several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

If you receive more than one supply of Acanya or Duac gel, store the unopened container in a refrigerator until you are ready to start using it. Do not freeze.

Once in use, store the gel at room temperature away from moisture and heat. Do not freeze. Throw away any unused medicine after the expiration date on the label has passed. Duac has an expiration date of 60 days. Acanya has an expiration date of 10 weeks. BenzaClin has an expiration date of 3 months.

What happens if I miss a dose?

Apply the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not use extra medicine to make up for the missed dose.

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What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms include bloody or watery diarrhea, which may occur if you absorb Neuac through your skin by applying too much.

Avoid using skin products that can irritate your skin, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.

Avoid using other medications on the areas you treat with Neuac unless your doctor instructs you to.

Antibiotic medicines can cause diarrhea, which may indicate a new infection. If you experience diarrhea that is watery or bloody, stop using Neuac and call your doctor. Do not use anti-diarrhea medicine unless your doctor advises you to.

Avoid exposure to sunlight or tanning beds. This medication can increase your risk of sunburn. Wear protective clothing and use sunscreen (SPF 30 or higher) when outdoors.

Avoid using sunscreen that contains PABA on the same skin treated with Neuac, or skin discoloration may occur.

Benzoyl peroxide can bleach hair or fabrics. Do not allow this medicine to come into contact with clothing, hair, or colored towels or bed linens.

This section was rewritten for readability and reviewed for meaning.

What other drugs will affect Neuac?

It is unlikely that other drugs you take by mouth or injection will affect benzoyl peroxide and clindamycin topical. However, many drugs can interact with each other. Inform all your health care providers about all the medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

This section was rewritten for readability and reviewed for meaning.

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.