Nexiclon XR

Nexiclon XR is used by itself or with other blood pressure medicines in adults to treat hypertension (high blood pressure).

Some extended-release forms of clonidine are used by themselves or with other medicines to treat attention deficit hyperactivity disorder (ADHD) in children who are 6 years old and older.

Nexiclon XR may also be used for reasons not mentioned in this medication guide.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may change your dose from time to time. Use the medicine exactly as directed.

Your dose may change if you switch to a different brand, strength, or form of this medicine. Avoid medication errors by using it exactly as directed on the label or as prescribed by your doctor.

Do not change your dose or stop using the medicine without your doctor's advice.

Nexiclon XR can be taken with or without food.

Swallow the extended-release tablet whole and do not crush, chew, or break it unless your doctor tells you to. Inform the doctor if the person taking this medicine has difficulty swallowing the tablet.

Measure liquid medicine with the provided measuring device (not a kitchen spoon).

Read and carefully follow the instructions that come with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

If you need surgery, inform the surgeon in advance that you are using Nexiclon XR. You may need to stop using the medicine for a short time.

Your heart rate, blood pressure, and other vital signs may need to be checked frequently.

You may experience withdrawal symptoms if you stop using Nexiclon XR suddenly. Consult your doctor before stopping the medicine.

Contact your doctor if you are sick with vomiting. This is especially important for a child taking Nexiclon XR.

You may be prescribed other medications to treat certain serious side effects. Continue taking these medicines for as long as your doctor has prescribed.

Store at room temperature away from moisture, heat, and light.

Dispose of the oral liquid after the number of days specified in the Instructions for Use after first opening the bottle, even if there is still medicine remaining.

Use only as directed. Inform your doctor if you are taking other medicines, have other medical conditions, or have allergies.

You should not use Nexiclon XR if you are allergic to it.

Tell your doctor if you have or have ever had:

• high or low blood pressure;
• fainting;
• heart problems, including heart attack, stroke, and heart rhythm disorder;
• pheochromocytoma (tumor of the adrenal gland);
• if you have ever had an allergic reaction to a Nexiclon XR transdermal skin patch; or
• kidney disease.

Dry eyes may occur while taking some formulations of clonidine, especially if you wear contact lenses. Talk with your doctor about this risk.

It is not known if Nexiclon XR will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

If you use Nexiclon XR for ADHD and become pregnant during treatment, talk with your doctor about registering with the National Pregnancy Registry to track the effects of clonidine on the baby.

Nexiclon XR may affect fertility in men and women. Pregnancy could be harder to achieve while either parent is using Nexiclon XR.

Ask a doctor if it is safe to breastfeed while using this medicine.

Get emergency medical help if you have signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.

Nexiclon XR may cause serious side effects. Call your doctor right away if you have:

• severe drowsiness and tiredness;
• slow heart rate;
• feeling like you might faint; or
• increased blood pressure--severe headache, blurred vision, pounding in your neck or ears.

Common side effects of Nexiclon XR may include:

• drowsiness, dizziness;
• feeling tired or irritable;
• dry mouth;
• constipation, loss of appetite; or
• sleep problems (insomnia), nightmares.

This is not a complete list of side effects and others may happen. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Skip the missed dose and take your next dose at the regular time. Do not take two doses at one time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include feeling cold, irritable, weak, drowsy, or light-headed, or having weak reflexes, pinpoint pupils, irregular heartbeats, depression, hallucinations, shallow breathing, or a seizure.

Drinking alcohol with Nexiclon XR can cause side effects.

Avoid driving or doing hazardous activities until you know how this medicine will affect you. Dizziness or drowsiness can lead to falls, accidents, or serious injuries.

Avoid becoming overheated or dehydrated during exercise and in hot weather.

Using Nexiclon XR with other drugs that make you drowsy can make you feel even more tired. Talk to your doctor before taking opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Inform your doctor about all your other medicines, especially:

• other heart or blood pressure medications;
• an antidepressant;
• antipsychotic medicine;
• any other medicines to treat ADHD; or
• any other medicine that contains Nexiclon XR.

This list is not complete. Other drugs may affect Nexiclon XR, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.