Night Time Pain

Acetaminophen is a pain reliever and helps reduce fever. Diphenhydramine is an antihistamine.

Night Time Pain is a combination medicine that treats occasional insomnia linked to minor aches and pains. Night Time Pain is not for treating sleeplessness without pain, or sleep issues that happen frequently.

Night Time Pain is also used for minor aches and pains such as headache, back pain, joint or muscle pain, tooth pain, or menstrual cramps.

Night Time Pain can also help with runny nose, sneezing, itchy nose and throat, and pain or fever caused by allergies, the common cold, or the flu.

Night Time Pain may also be used for other reasons not mentioned in this medication guide.

Use exactly as directed on the label, or as prescribed by your doctor. Night Time Pain is only for short-term use until your symptoms improve.

Do not take more of Night Time Pain than is recommended. An overdose of acetaminophen can harm your liver or cause death. Taking too much diphenhydramine can lead to serious heart issues, seizures, coma, or death.

Night Time Pain is not for use in anyone younger than 12 years old. Do not use the medicine to make a child sleepy. Death can occur from the misuse of antihistamines in very young children.

Do not use this medicine for longer than 2 weeks to treat sleep problems, or longer than 7 days to treat cold or allergy symptoms.

Call your doctor if you still have a fever after 3 days, or if you still have pain after 10 days (or 5 days if you are 12-17 years old). Also call your doctor if your symptoms worsen, or if you have any redness or swelling.

If you need surgery or medical tests, tell the doctor in advance if you have taken this medicine in the past few days.

Store at room temperature away from moisture and heat.

Use Night Time Pain exactly as directed. Taking too much acetaminophen can harm your liver or lead to death. Taking too much diphenhydramine can cause serious heart issues, seizures, coma, or death.

Do not use this medicine to make a child sleepy. This medicine is not for anyone younger than 12 years old.

Ask a doctor or pharmacist before using any other medicine that may have acetaminophen or diphenhydramine. Taking too much of either can result in a fatal overdose.

Drinking alcohol may increase your chances of liver damage while using acetaminophen.

Stop taking this medicine and call your doctor immediately if you notice skin redness or a rash that spreads and leads to blistering and peeling.

Ask a doctor before taking medicine that contains acetaminophen if you have ever had liver disease, or if you drink more than 3 alcoholic beverages per day.

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

• liver disease;
• an enlarged prostate or urination problems;
• asthma, chronic obstructive pulmonary disease (COPD), emphysema, or other breathing disorder;
• glaucoma; or
• a condition for which you take warfarin (Coumadin, Jantoven).

Ask a doctor before using this medicine if you are pregnant or breastfeeding. Diphenhydramine may slow breast milk production.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you should never again take any medicine that contains acetaminophen.

The medicine may cause serious side effects. Stop using the medicine and call your doctor at once if you have:

• severe drowsiness;
• painful or difficult urination; or
• liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects of Night Time Pain may include:

• drowsiness;
• constipation;
• decreased urination;
• dry eyes, blurred vision; or
• dry mouth, nose, or throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Since Night Time Pain is taken as needed, you might not have a regular dosing schedule. If you miss a dose and it's close to the time for your next dose, just skip the missed dose. Do not take two doses at once.

Seek emergency medical help or call the Poison Help line at 1-800-222-1222. An overdose can be fatal or cause liver damage.

Signs of an overdose may include loss of appetite, vomiting, weakness, confusion, ringing in your ears, upper stomach pain, dark urine, not urinating, very dry eyes and mouth, yellowing of your skin or eyes, dilated pupils, fast heartbeat, tremors, agitation, hallucinations, or seizures.

Avoid driving or doing anything dangerous until you know how Night Time Pain will affect you. Your reactions might be slowed down.

Ask a doctor or pharmacist before taking any other medicine that may have acetaminophen or diphenhydramine in it. This includes medicines for pain, fever, swelling, cold/flu symptoms, or anti-itch medicine applied to the skin. Taking too much acetaminophen or diphenhydramine can lead to a fatal overdose.

Drinking alcohol may raise your risk of liver damage while using acetaminophen.

Ask a doctor or pharmacist before using Night Time Pain with any other medicines, especially those that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Inform your doctor about all the medicines you are currently taking and any new medicine you begin or discontinue. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.