Nix Creme Rinse (Topical)

Permethrin 1% lotion is used to treat head lice. It works by killing both the lice and their eggs. The 5% cream is used to treat scabies by killing the mites that cause scabies.

To stop reinfection or spreading the infection to others, you need to follow good health habits. These include:

• Machine wash all clothing (including hats, scarves, and coats), bedding, towels, and washcloths in very hot water and dry them using the hot cycle of a dryer for at least 20 minutes. Clothing or bedding that cannot be washed should be dry cleaned or sealed in an airtight plastic bag for 2 weeks.
• Shampoo all wigs and hairpieces.
• Wash all hairbrushes and combs in very hot soapy water (above 130 °F) for 5 to 10 minutes and do not share them with other people.
• Clean the house or room by thoroughly vacuuming upholstered furniture, rugs, and floors.
• Wash all toys in very hot soapy water (above 130 °F) for 5 to 10 minutes or seal in an airtight plastic bag for 2 weeks. This is especially important for stuffed toys used on the bed.

In deciding to use a medicine, you and your doctor need to consider the risks compared to the benefits. For this medicine, please keep the following in mind:

Allergies

Inform your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also, let your healthcare professional know if you have any other allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Research on this medicine has only been conducted with adult patients, and there is no specific information comparing the use of topical permethrin in children to its use in other age groups.

Geriatric

Many medicines have not been specifically studied in older adults. Therefore, it may not be clear if they work the same way as they do in younger adults or if they cause different side effects or issues in older adults. There is no specific information comparing the use of topical permethrin in elderly patients to its use in other age groups.

Breast Feeding

Studies suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Some medicines should not be used together at all, while in other cases, two different medicines may be used together even if an interaction might happen. In these situations, your doctor may adjust the dose, or other precautions may be needed. Inform your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be taken at or around the time of eating food or certain types of food due to possible interactions. Using alcohol or tobacco with certain medicines may also lead to interactions. Talk to your healthcare professional about using your medicine with food, alcohol, or tobacco.

Other Medical Problems

Having other medical problems may affect the use of this medicine. Be sure to tell your doctor if you have any other medical issues, especially:

The presence of other medical problems may affect the use of topical permethrin. Make sure you inform your doctor if you have other medical issues, especially:

• Severe inflammation of the scalp—Using permethrin may worsen the condition.

Along with its needed effects, a medicine may cause some unwanted effects. Not all of these side effects may happen, but if they do, they may require medical attention.

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body gets used to the medicine. Your health care professional may also have ways to help prevent or reduce some of these side effects. Contact your health care professional if any of the following side effects continue, are bothersome, or if you have any questions about them:

Less common or rare

• Burning, itching, numbness, rash, redness, stinging, swelling, or tingling of the scalp

Other side effects not listed may also happen in some patients. If you notice any other effects, consult your healthcare professional.

Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Acticin
• Elimite
• Nix Creme Rinse

In Canada

• Nix
• Nix Dermal Cream
• Nix Lice Killing Creme Rinse

Available Dosage Forms:

• Lotion
• Cream
• Liquid

Therapeutic Class: Pediculicide

Chemical Class: Pyrethroid

Keep this medicine away from the eyes. If you accidentally get some in your eyes, flush them thoroughly with water at once.

Permethrin lotion which is used to treat lice, comes in a container that holds only one treatment. Use as much of the medicine as you need and discard any remaining lotion properly.

For the treatment of head lice (1% lotion):

• Shampoo the hair and scalp using regular shampoo.
• Thoroughly rinse and towel dry the hair and scalp.
• Allow hair to air dry for a few minutes.
• Shake the permethrin lotion well before applying.
• Thoroughly wet the hair and scalp with the permethrin lotion. Be sure to cover the areas behind the ears and on the back of the neck also. Allow the lotion to remain in place for 10 minutes.
• Then, rinse the hair and scalp thoroughly and dry with a clean towel.
• When the hair is dry, you may want to comb the hair with a fine-toothed comb to remove any remaining nits (eggs) or nit shells.

Head lice can be easily transferred from one person to another by direct contact with clothing, hats, scarves, bedding, towels, washcloths, hairbrushes and combs, or hairs from infected persons. Therefore, all members of your household should be examined for head lice and should receive treatment if they are found to be infected. If you have any questions about this, check with your doctor.

For the treatment of scabies (5% cream):

• Read package directions carefully before using.
• Thoroughly wash and dry skin.
• Massage the cream into the skin from the head to the soles of the feet, paying special attention to creases in the skin, hands, feet, between fingers and toes, underarms, and groin.
• Scabies rarely infests the scalp of adults, although the hairline, neck, side of the head, and forehead may be infested in older people and in infants. Infants should be treated on the scalp, side of the head, and forehead.
• Leave the permethrin cream on the skin for 8 to 14 hours.
• Wash off by taking a shower or bath.
• Change into clean clothes.
• After treatment, itching may continue for up to 4 weeks.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For topical dosage forms (cream and lotion): For head lice: Adults and children 2 years of age and older—Apply to the hair and scalp one time. Children up to 2 years of age—Use and dose must be determined by your doctor. For scabies: Adults and children 2 months of age and older—Apply to the skin one time. Children up to 2 months of age—Use and dose must be determined by your doctor.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

• Can you use Nix (permethrin) lice shampoo on your body as a lotion to kill scabies?