Nymalize

Nymalize is a calcium channel blocker that helps prevent brain damage from reduced blood flow to the brain due to an aneurysm (a swollen or burst blood vessel in the brain).

Nymalize may also be used for reasons not mentioned in this medication guide.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Nymalize is usually taken for 21 days in a row. Follow your doctor's dosing instructions very carefully.

Take Nymalize on an empty stomach, at least 1 hour before or 2 hours after a meal.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Swallow the capsule whole with water or other liquid. Avoid grapefruit juice.

If the person taking Nymalize cannot swallow the capsule, the medicine from inside the capsule can be given through a nasogastric (NG) feeding tube. A healthcare provider can teach you how to properly give the medicine through an NG tube. Read and carefully follow all instructions given to you. Ask your doctor or pharmacist if you do not understand these instructions.

The liquid from a Nymalize capsule should never be injected through a needle into the body, or death may occur. These medicine capsules are to be taken only by mouth or through an NG tube.

Your blood pressure and heart rate will need to be checked often.

Store at room temperature away from moisture, heat, and light. Do not freeze. Keep each capsule in the original package until you are ready to take one.

Tell your doctor about all your current medicines and any that you start or stop using. Many drugs can interact, and some drugs should not be used together.

The liquid from a Nymalize capsule should never be injected through a needle into the body, or death may occur.

You should not use Nymalize if you are allergic to it.

Some medicines can cause unwanted or dangerous effects when used with Nymalize. Your doctor may change your treatment plan if you also use:

• nefazodone;
• an antibiotic—clarithromycin, telithromycin;
• antifungal medicine—itraconazole, ketoconazole; or
• antiviral medicine to treat HIV/AIDS—indinavir, nelfinavir, ritonavir, saquinavir.

Tell your doctor if you have ever had:

• cirrhosis or other liver disease; or
• heart disease; or
• high blood pressure (especially if you take blood pressure medication).

It is not known whether Nymalize will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breastfeed while using this medicine.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Nymalize may cause serious side effects. Call your doctor right away if you experience:

• a light-headed feeling, as if you might pass out;
• fast or slow heart rate; or
• swelling in your ankles or feet.

Common side effects of Nymalize may include:

• low blood pressure (feeling light-headed);
• nausea, upset stomach;
• slow heartbeats; or
• muscle pain.

This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Take the medicine as soon as possible, but skip the missed dose if it is close to the time for your next dose. Do not take two doses at the same time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

• Grapefruit may interact with Nymalize and lead to unwanted side effects. Avoid the use of grapefruit products.

• Avoid taking an herbal supplement containing St. John's wort.

Sometimes, it is not safe to use certain medications together. Some drugs can change how much of other drugs is in your blood, which may increase side effects or make the medications work less well.

Many drugs can affect Nymalize, and some should not be used together. Tell your doctor about all the medicines you are currently taking and any new medicine you start or stop. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.