On this page · 8 sections

Nyquil Cough DM + Congestion

Generic name: dextromethorphan, doxylamine, and phenylephrine

Used for common cold
Last updated November 3, 2026 0 views
Share

What is Nyquil Cough DM + Congestion?

Nyquil Cough DM + Congestion is a combination medicine that helps relieve cough, runny or stuffy nose, and sneezing caused by the common cold or the flu.

Nyquil Cough DM + Congestion may also be used for reasons not mentioned in this medication guide.

This section was rewritten for readability and reviewed for meaning.

How should I take Nyquil Cough DM + Congestion?

Use exactly as directed on the label, or as prescribed by your doctor. Cold or cough medicine is only for short-term use.

Do not give this medicine to a child without medical advice. Follow all directions when giving this medicine to a child. Do not use the medicine to make a child sleepy. Misuse of this medicine may cause death in very young children.

Measure liquid medicine with the supplied measuring device (not a kitchen spoon).

Call your doctor if your symptoms do not improve after 7 days, or if you have a fever, rash, or headaches.

Store at room temperature away from moisture and heat.

This section was rewritten for readability and reviewed for meaning.

Warnings

Do not use this medicine if you are using or if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

This section was rewritten for readability and reviewed for meaning.

Before taking this medicine

Do not use Nyquil Cough DM + Congestion if you are using or have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

Ask a doctor or pharmacist if this medicine is safe to use if you have:

  • cough with mucus, or cough caused by emphysema or chronic bronchitis;
  • high blood pressure, heart disease;
  • glaucoma;
  • a thyroid disorder;
  • diabetes;
  • urination problems due to an enlarged prostate; or
  • if you are on a low-salt diet.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

This section was rewritten for readability and reviewed for meaning.

Nyquil Cough DM + Congestion side effects

Get emergency medical help if you have signs of an allergic reaction: hives, trouble breathing, swelling of your face, lips, tongue, or throat.

Stop using Nyquil Cough DM + Congestion and call your doctor right away if you have:

  • dizziness;
  • nervousness; or
  • sleep problems (insomnia).

Less serious side effects may happen more often, and you may not have any at all.

This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

This section was rewritten for readability and reviewed for meaning.

What happens if I miss a dose?

Nyquil Cough DM + Congestion is used as needed. If you miss a dose while on a dosing schedule, skip it. Do not take two doses at once.

This section was rewritten for readability and reviewed for meaning.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

  • Drinking alcohol with Nyquil Cough DM + Congestion can cause side effects.
  • Ask a doctor or pharmacist before taking other cough or cold medicines that may contain similar ingredients.
  • Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

This section was rewritten for readability and reviewed for meaning.

What other drugs will affect Nyquil Cough DM + Congestion?

Ask a doctor or pharmacist before using any other medicines that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures).

Tell your doctor about all other medicines you use.

This includes prescription and over-the-counter medicines, vitamins, and herbal products.

Not all possible interactions are listed here.

This section was rewritten for readability and reviewed for meaning.

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
General medicine information Consumer-friendly language

Content is provided for education and is not medical advice. See our medical disclaimer.