Obiltoxaximab (Intravenous)

Obiltoxaximab injection is used along with antibiotics to treat inhalational anthrax. It is also used to prevent inhalational anthrax after someone has been exposed. Obiltoxaximab works by stopping the anthrax bacteria from getting into the body's cells, which helps prevent an infection.

This medicine is to be given only by or under the direct supervision of your doctor.

Your doctor will monitor your progress closely while you receive this medicine. This will help your doctor determine if the medicine is effective and to look for any unwanted effects.

This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and needs immediate medical attention. Contact your nurse or doctor right away if you experience very fast or irregular breathing, a very fast or irregular heartbeat, a rash, fainting, hive-like swellings on the skin, or swelling of the eyelids or around the eyes, face, lips, or tongue.

In deciding to use a medicine, you and your doctor need to consider the risks of taking it versus the benefits it will provide. For this medicine, keep the following in mind:

Allergies

Inform your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also let your healthcare professional know if you have any other types of allergies, like to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

So far, studies have not shown any specific problems in children that would limit the use of obiltoxaximab injection.

Geriatric

So far, studies have not shown any specific problems in the elderly that would limit the use of obiltoxaximab injection.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication during breastfeeding. Consider the potential benefits and risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should never be used together, while others may be combined even if interactions could happen. In these situations, your doctor may need to adjust the dose or take other precautions. Inform your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be taken at or near mealtime, or with specific types of food due to possible interactions. Using alcohol or tobacco with certain medicines may also lead to interactions. Talk with your healthcare professional about how to use your medicine with food, alcohol, or tobacco.

Along with its necessary effects, a medicine may cause some unwanted effects. Not all of these side effects may happen, but if they do, they might need medical attention.

Check with your doctor or nurse right away if any of the following side effects occur:

More common

• Chest discomfort
• cough
• difficulty swallowing
• dizziness
• fainting or loss of consciousness
• fast heartbeat
• fast or irregular breathing
• hives, itching, or skin rash
• swelling of the eyelids or around the eyes, face, lips, or tongue
• trouble breathing
• unusual tiredness or weakness

Some side effects may happen that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue, are bothersome, or if you have any questions about them:

More common

• Headache

Less common

• Body aches or pain
• chills
• ear congestion
• fever
• loss of voice
• nasal congestion
• pain, bruise, or swelling at the injection site
• pain in the arms or legs
• runny nose
• sneezing
• sore throat

Less common or rare

• Bone pain
• difficulty with moving
• dry mouth
• muscle aching or cramping
• muscle pains or stiffness
• swollen joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Anthim

Pharmacologic Class: Monoclonal Antibody

A nurse or other trained health professional will give you this medicine. The medicine is given through a needle placed in a vein.

You may also receive medicines (eg, diphenhydramine, Benadryl®) before you receive obiltoxaximab to help prevent allergic reactions to the injection.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.