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Topical anti-rosacea agents topical cream (1%)

Oxymetazoline topical

Generic name: oxymetazoline topical

Brand names: Rhofade

Used for rosacea
Last updated November 3, 2026 0 views
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What is oxymetazoline topical?

Oxymetazoline is a decongestant that reduces the size of blood vessels. Enlarged blood vessels under the skin can lead to redness.

Oxymetazoline topical (for the skin) is used to treat facial redness caused by rosacea.

Oxymetazoline topical may also be used for other reasons not mentioned in this medication guide.

This section was rewritten for readability and reviewed for meaning.

How should I use oxymetazoline topical?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Do not take by mouth. Topical medicine is for use only on the skin. Do not use this medicine on open wounds or irritated skin. If this medicine gets in your eyes, nose, mouth, or vagina, rinse with water.

Apply a thin layer of medication to cover the entire face. Do not apply near your eyes or mouth.

Wash your hands after applying this medicine.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

Call your doctor if your symptoms do not improve, or if they get worse.

Store at room temperature away from moisture and heat.

This section was rewritten for readability and reviewed for meaning.

Warnings

Do not take by mouth. Oxymetazoline topical is for use only on the skin.

Rinse with water if oxymetazoline topical gets in your eyes.

This section was rewritten for readability and reviewed for meaning.

Before taking this medicine

You should not use oxymetazoline topical if you are allergic to oxymetazoline.

To make sure oxymetazoline topical is safe for you, tell your doctor if you have:

  • heart disease, high blood pressure;
  • blood circulation problems;
  • glaucoma; or
  • peripheral vascular disease such as Raynaud's syndrome, Buerger's disease, scleroderma, or Sjögren's syndrome.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether oxymetazoline topical passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

Oxymetazoline topical is not approved for use by anyone younger than 18 years old.

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Oxymetazoline topical side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

oxymetazoline topical may cause serious side effects. Stop using oxymetazoline topical and call your doctor right away if you have:

  • worsening of your rosacea symptoms;
  • numbness, tingling, or cold feeling in your hands or feet;
  • pale or purple appearance in your fingers or toes; or
  • blurred vision, tunnel vision, eye pain, or seeing halos around lights.

Common side effects of oxymetazoline topical may include:

  • skin redness or itching;
  • pain; or
  • other skin reactions.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This section was rewritten for readability and reviewed for meaning.

Oxymetazoline topical dosing information

Usual Adult Dose for Acne Rosacea:

Apply a thin layer to cover the entire face (e.g., forehead, nose, cheeks, chin) once a dayComments:-The eyes and lips should be avoided during application.-Patients should wash their hands immediately after application.Use: Topical treatment of persistent facial erythema associated with rosacea

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

This section was rewritten for readability and reviewed for meaning.

What happens if I overdose?

An overdose of oxymetazoline topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

Avoid getting oxymetazoline topical in your eyes or mouth.

This section was rewritten for readability and reviewed for meaning.

What other drugs will affect oxymetazoline topical?

Other drugs may interact with oxymetazoline topical, including prescription and over-the-counter medicines, vitamins, and herbal products. Inform each of your health care providers about all medicines you are currently using and any medicine you begin or stop using.

This section was rewritten for readability and reviewed for meaning.

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.