Pavblu Prefilled Syringe

Aflibercept is used in adults to treat wet age-related macular degeneration, swelling in the retina due to blocked retinal veins, and eye issues caused by diabetes, such as diabetic macular edema.

Eylea is also used to treat eye problems in preterm babies who were born premature.

Aflibercept may also be used for reasons not mentioned in this medication guide.

You should not receive aflibercept if you have swelling, redness, pain inside your eyes, or any type of infection in or around your eyes.

Call your doctor immediately if you have eye pain or redness, swelling or puffiness around your eyes, or sudden vision problems at any time during treatment.

You should not use aflibercept if you are allergic to it, or if you have:

• swelling, redness, or pain inside or around your eyes; or
• any type of infection (bacterial, fungal, viral) in or around your eyes.

Tell your doctor if you have or have ever had:

• inflammation of the eye or retina, retinal detachment;
• a heart attack or stroke; or
• glaucoma or another condition that increases pressure inside your eyes.

It is not known if aflibercept will harm an unborn baby. Use effective birth control while using aflibercept and for at least 3 to 4 months after your last dose, depending on the brand used. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using Pavblu Prefilled Syringe.

Get emergency medical help if you have signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.

Pavblu Prefilled Syringe may cause serious side effects. Call your doctor right away if you have:

• eye pain or redness, swelling around your eyes;
• changes in your vision, increased sensitivity to light;
• seeing flashes of light or "floaters" in your vision, seeing halos around lights; or
• chest pain, sudden numbness or weakness (especially on one side of the body), or sudden severe headache, confusion, or problems with speech or balance.

Common side effects of Pavblu Prefilled Syringe may include:

• bleeding in the back of the eye (retina);
• blurred vision, eye pain, discomfort, or redness, seeing halos around lights;
• seeing flashes of light or "floaters" in your vision;
• increased pressure inside the eye; or
• blood spots on the white of your eye.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Follow all directions on your prescription label and read all medication guides or instruction sheets.

Aflibercept is given as an injection into your eye. Your doctor will use a medicine to numb your eye before giving you the injection. You will receive this injection in your doctor's office or other clinic setting.

For some time after your injection, your eyes will be checked periodically to make sure the injection has not caused any side effects.

Your doctor will also need to check your progress on a regular basis and determine if any additional treatment is needed.

Aflibercept is given at different intervals, depending on the condition being treated with this medicine. Follow your doctor's dosing instructions very carefully.

Call your doctor for guidance if you miss an appointment for your aflibercept injection.

In a medical setting, it is unlikely that you will miss a dose.

Pavblu Prefilled Syringe may cause blurred vision and may affect your reactions. Avoid driving or doing dangerous activities until you understand how this medicine will affect you.

Medicine used in the eyes is not likely to be affected by other drugs you use. However, many drugs can interact. Tell your doctor about all your current medicines, including prescription and over-the-counter medicines, vitamins, and herbal products.

Find detailed information on biosimilars for this medication.