Phoslyra

Calcium is a mineral essential for various body functions, particularly in forming and maintaining bones. Calcium can also attach to other minerals like phosphate and help remove them from the body.

Phoslyra is used to manage phosphate levels in people with kidney failure who are receiving dialysis, preventing these levels from becoming too high.

Phoslyra may also be used for reasons not mentioned in this medication guide.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Take the capsule with food.

You may need to keep a food diary to track how much calcium you are getting in your diet.

You may need frequent medical tests. Even if you have no symptoms, tests can help your doctor determine if Phoslyra is effective.

Store at room temperature away from moisture and heat.

You should not use Phoslyra if you have high levels of calcium in your blood.

You should not use Phoslyra if you are allergic to it, or if you have high levels of calcium in your blood.

Tell your doctor if:

• your kidney disease gets worse; or
• you also take digoxin (digitalis, Lanoxin).

Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether Phoslyra will harm an unborn baby, but having kidney failure or developing hypercalcemia during pregnancy may cause complications for both the baby and the mother. The benefits of using this medicine during pregnancy may outweigh any risks.

Tell your doctor if you are breastfeeding.

Phoslyra is not approved for use by anyone younger than 18 years old.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Phoslyra may cause serious side effects. Stop using Phoslyra and call your doctor right away if you have:

• high levels of calcium in your blood--nausea, vomiting, constipation, increased thirst or urination, muscle weakness, bone pain, confusion, lack of energy, or feeling tired.

Common side effects of Phoslyra may include:

• increased calcium in the blood
• nausea; or
• diarrhea.

This is not a complete list of side effects, and others may happen. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Take the medicine as soon as you remember, but if it is nearly time for your next dose, skip the missed dose. Do not take two doses at once.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Do not take extra calcium supplements unless your doctor has instructed you to.

Check with your doctor before using an antacid, and only use the type your doctor suggests. Some antacids have calcium in them.

If you take any of the following medicines, take them separately from your dose of calcium acetate:

• A fluoroquinolone antibiotic: Take your Phoslyra dose 6 hours before or 2 hours after you take an antibiotic such as ciprofloxacin, moxifloxacin, levofloxacin, Cipro, or Levaquin.
• A tetracycline antibiotic: Take your Phoslyra dose 1 hour before or 1 hour after you take an antibiotic such as doxycycline, minocycline, tetracycline, Doryx, or Oracea.
• Thyroid medication: Take your Phoslyra dose 4 hours before or 4 hours after you take the thyroid medicine.

Other drugs may affect Phoslyra, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.