Phosphocol P-32 (Injection)

Chromic phosphate P 32 is a radiopharmaceutical. Radiopharmaceuticals are agents used to diagnose certain medical problems or treat certain diseases.

Chromic phosphate P 32 is used to treat cancer or related issues. It is delivered through a catheter into the pleura (the sac surrounding the lungs) or into the peritoneum (the sac surrounding the liver, stomach, and intestines) to help manage fluid leakage in these areas caused by cancer. It may also be given by injection to treat cancer in specific organs such as the ovaries and prostate.

Chromic phosphate P 32 must be given only by or under the direct supervision of a doctor who has specialized training in nuclear medicine.

In deciding to use a medicine, you and your doctor need to consider the risks of taking the medicine against the benefits it may provide. For this medicine, please consider the following:

Allergies

Inform your doctor if you have ever had any unusual or allergic reactions to this medicine or any other medicines. Also, let your healthcare professional know if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

There is no specific information comparing the use of chromic phosphate P 32 in children with its use in other age groups.

Geriatric

Many medicines have not been studied specifically in older adults. Therefore, it may not be known whether they work in the same way they do in younger adults. Although there is no specific information comparing the use of chromic phosphate P 32 in the elderly with its use in other age groups, this medicine is not expected to cause different side effects or problems in older adults than it does in younger adults.

Interactions with Medicines

Some medicines should never be used together, while in other cases, two different medicines may be used together even if an interaction might happen. In these situations, your doctor may want to adjust the dose, or other precautions may be necessary. Inform your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Some medicines should not be taken at or around the time of eating food or certain types of food because interactions may occur. Using alcohol or tobacco with certain medicines may also lead to interactions. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Along with its necessary effects, a medicine can cause some unwanted effects. Not all of these side effects may happen, but if they do, they might require medical attention.

Check with your doctor right away if any of the following side effects occur:

Less common or rare

• Severe abdominal or stomach pain
• Chest pain
• Chills and/or fever
• Dry cough
• Severe nausea and vomiting
• Sore throat and fever
• Trouble breathing
• Unusual bleeding or bruising
• Unusual tiredness or weakness

Some side effects may happen that usually do not need medical attention. These side effects may go away during treatment as your body gets used to the medicine. Your health care professional may also be able to suggest ways to prevent or lessen some of these side effects. Check with your health care professional if any of the following side effects persist, are bothersome, or if you have any questions about them:

More common

• Abdominal or stomach cramps
• Diarrhea
• Feeling of discomfort
• Loss of appetite
• Nausea and vomiting
• Weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Phosphocol P-32

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.