Plasminogen (human)

Plasminogen (human) is used to raise plasminogen levels in individuals with plasminogen deficiency type 1 (hypoplasminogenemia).

Plasminogen (human) may also be used for reasons not mentioned in this medication guide.

Use only as directed. Inform your doctor if you are taking other medicines, have other medical conditions, or have allergies.

You should not use plasminogen (human) if you are allergic to it.

Tell your doctor if you have ever had:

• bleeding problems.

Plasminogen is made from human plasma (part of the blood) which may carry viruses that could cause disease. Talk with your doctor about the risks and benefits of using plasminogen.

Tell your doctor if you are pregnant or breastfeeding.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Seek emergency medical help if you have bloody or tarry stools, vomit blood, or have any heavy bleeding that does not stop after 30 minutes of direct pressure.

Plasminogen may cause serious side effects. Call your doctor right away if you have:

• trouble breathing, wheezing, cough;
• changes in your speech; or
• pain in your pelvic area, groin, stomach, or back.

Common side effects of plasminogen may include:

• stomach pain, nausea, constipation, bloating;
• joint pain, back pain, pain in your hands or feet;
• tiredness;
• dizziness;
• headache;
• dry mouth; or
• bleeding.

This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Plasminogen (human) is injected slowly into a vein through an IV over 10 to 30 minutes.

You may receive this medicine at a medical setting, at home from a caregiver, or by injecting it yourself.

Your doctor will tell you how often to use this medicine and how much to use each time.

Your blood may need to be tested often.

Store plasminogen (human) vials at room temperature or in a refrigerator. Do not freeze.

Store other supplies at room temperature.

Call your doctor for instructions if you miss a dose.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Follow your doctor's instructions regarding any restrictions on food, drinks, or activities.

Other drugs may affect plasminogen (human), including prescription and over-the-counter medicines, vitamins, and herbal products. Inform your doctor about all other medicines you are using.