Potassium phosphate

Phosphorus is a natural substance that is essential for every cell in the body. Phosphorus is found in all body cells and is needed for the growth and repair of cells and tissues.

Potassium phosphate is used to treat or prevent hypophosphatemia (low blood levels of phosphorus). Potassium phosphate is sometimes added to intravenous (IV) fluids for people who cannot eat or drink anything.

Potassium phosphate may also be used for reasons not mentioned in this medication guide.

Potassium phosphate is given through an infusion into a vein. A healthcare provider will give you your first dose and may teach you how to use the medication on your own.

Read and carefully follow any Instructions for Use that come with your medicine. Ask your doctor or pharmacist if you do not understand any instructions.

Potassium phosphate must be mixed with a liquid (diluent) before using it. If you are giving injections by yourself, make sure you know how to mix and store the medicine correctly.

Prepare an injection only when you are ready to use it. Do not use the medicine if it has changed color or has particles in it. Call your pharmacist to get new medicine.

You will need frequent medical tests.

Store at room temperature, away from moisture, heat, and light.

You should not use potassium phosphate if you have low levels of calcium, or high levels of potassium or phosphorus in your body.

You should not use potassium phosphate if you have:

• high levels of potassium in your blood (hyperkalemia);
• low levels of calcium in your blood (hypocalcemia); or
• high levels of phosphorus in your blood (hyperphosphatemia).

Tell your doctor if you have ever had:

• heart disease;
• kidney disease; or
• Addison's disease (an adrenal gland disorder).

Tell your doctor if you are pregnant or breastfeeding.

Do not give potassium phosphate to a child younger than 4 years old without a doctor's advice.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have any signs of electrolyte imbalance, such as:

• confusion, severe weakness;
• a light-headed feeling, like you might pass out;
• nausea, chest pain, irregular heartbeats;
• numbness or tingling in your arms or legs;
• weakness or heavy feeling in your legs;
• loss of movement in any part of your body; or
• slow heart rate, weak pulse, fainting, slow breathing.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Usual Adult Dose for Hypophosphatemia:

Hypophosphatemia: Dose and rate of administration are dependent on individual patient needsTotal parenteral nutrition: 12 to 15 millimolar phosphorous is recommended for each 500 mL 50% dextrose injection-Keep in mind the amount of potassium being infused; monitor serum potassium and/or electrocardiographic changes as neededComments:-Must be diluted before administration.

Usual Pediatric Dose for Hypophosphatemia:

Hypophosphatemia: Dose and rate of administration are dependent on individual patient needsInfants receiving total parenteral nutrition: 1.5 to 2 millimolar phosphorous/kg/day-Keep in mind the amount of potassium being infused; monitor serum potassium and/or electrocardiographic changes as neededComments:-Must be diluted before administration.

Call your doctor for instructions if you miss a dose.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Avoid taking a vitamin or mineral supplement that contains calcium or vitamin D, unless your doctor tells you to.

Ask your doctor before using an antacid, and use only the type your doctor recommends. Some antacids can make it harder for your body to absorb potassium phosphate.

Tell your doctor about all your other medicines, especially:

• digoxin, digitalis; or
• a diuretic or "water pill."

This list is not complete. Other drugs may affect potassium phosphate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.