Potassium phosphate and sodium phosphate

Phosphorus is a natural substance that is essential for every cell in the body. Most of the phosphorus in the body is located in the bones. The forms of phosphorus combined with potassium and sodium are called phosphates.

Potassium phosphate and sodium phosphate is a combination medicine that makes the urine more acidic to help prevent kidney stones.

Potassium phosphate and sodium phosphate may also be used for other reasons not mentioned in this medication guide.

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take this medicine with a full glass of water.

Potassium phosphate and sodium phosphate works best if you take it with meals and at bedtime.

While using this medicine, you may need frequent blood or urine tests.

The powder form must be mixed with water before you take it. Mix 1 packet of the powder with about 1/3 cup (2.5 ounces) of water and stir until completely dissolved. Swallow the mixture right away after mixing. Do not save for later use.

The tablet form may need to be dissolved in water, or swallowed whole. Carefully follow any dosing instructions provided with your medicine.

If you have a history of kidney stones, it is possible that you will pass old stones after starting treatment with potassium phosphate and sodium phosphate.

Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

You should not take potassium phosphate and sodium phosphate if you have severe kidney disease, or high levels of phosphorus in your body.

You should not take potassium phosphate and sodium phosphate if you are allergic to it, or if you have:

• severe kidney disease; or
• high levels of phosphorus in your blood (hyperphosphatemia).

To make sure this medicine is safe for you, tell your doctor if you have:

• a history of kidney stones in the distant past;
• kidney disease;
• cirrhosis or other liver disease;
• high blood levels of potassium (hyperkalemia), calcium (hypercalcemia), or sodium (hypernatremia);
• heart disease, high blood pressure;
• toxemia of pregnancy;
• Addison's disease (an adrenal gland disorder);
• breathing problems;
• pancreas disorder;
• thyroid disorder;
• swelling in your hands or feet;
• if you are dehydrated; or
• if you take a diuretic or "water pill."

FDA pregnancy category C. It is not known whether potassium phosphate and sodium phosphate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether this medicine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Potassium phosphate and sodium phosphate should not be given to a child younger than 4 years old without a doctor's advice.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Potassium phosphate and sodium phosphate may cause serious side effects. Call your doctor right away if you have:

• severe or ongoing diarrhea;
• seizures (convulsions);
• shortness of breath; or
• signs of a kidney problem—little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath.

Common side effects of potassium phosphate and sodium phosphate may include:

• nausea, vomiting, stomach pain, diarrhea;
• bone or joint pain;
• headache, dizziness, feeling tired;
• muscle pain or weakness;
• increased thirst; or
• numbness or tingling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Usual Adult Dose for Hypophosphatemia:

1 or 2 tablets/capsules orally four times a day (with meals and bedtime)Comments:-As a phosphorous supplement, each tablet supplies 25% of the US Recommended Daily Allowance (US RDA) of phosphorous for adults.Use(s): Increase urinary phosphate and pyrophosphate; phosphorous supplement

Usual Adult Dose for Urinary Acidification:

1 or 2 tablets/capsules orally four times a day (with meals and bedtime)Comments:-As a phosphorous supplement, each tablet supplies 25% of the US Recommended Daily Allowance (US RDA) of phosphorous for adults.Use(s): Increase urinary phosphate and pyrophosphate; phosphorous supplement

Usual Pediatric Dose for Hypophosphatemia:

4 years and older: 1 tablet orally four times a day (with meals and bedtime)Comments:-As a phosphorous supplement, each tablet supplies 25% of the US Recommended Daily Allowance (US RDA) of phosphorous for children over 4 and adults.Uses: Increase urinary phosphate and pyrophosphate; phosphorous supplement

Usual Pediatric Dose for Urinary Acidification:

4 years and older: 1 tablet orally four times a day (with meals and bedtime)Comments:-As a phosphorous supplement, each tablet supplies 25% of the US Recommended Daily Allowance (US RDA) of phosphorous for children over 4 and adults.Uses: Increase urinary phosphate and pyrophosphate; phosphorous supplement

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not take extra medicine to make up for the missed dose.

Seek emergency medical help or call the Poison Help line at 1-800-222-1222.

Signs of overdose may include numbness or a tingling sensation, muscle stiffness or feeling weak, loss of movement, confusion, a heavy feeling in your legs, irregular heartbeats, or feeling faint.

Talk to your doctor before using an antacid, and only use the type your doctor suggests. Some antacids can make it harder for your body to absorb potassium phosphate and sodium phosphate.

Do not take a vitamin or mineral supplement that contains calcium or vitamin D, unless your doctor advises you to.

Do not use potassium supplements or salt substitutes while taking potassium phosphate and sodium phosphate, unless your doctor has instructed you to do so.

Other drugs may interact with potassium phosphate and sodium phosphate, including prescription and over-the-counter medicines, vitamins, and herbal products. Inform all your health care providers about all the medicines you are currently using and any medicines you begin or stop using.