Precedex (injection)

Precedex is used in adults to begin or continue sedation for patients on a breathing machine (ventilator) in the intensive care unit (ICU).

Precedex is used in adults for sedation before and during surgery or a medical procedure.

Precedex is also used in children aged 1 month to less than 18 years for sedation before and during other medical procedures.

Precedex may also be used for reasons not mentioned in this medication guide.

Use only as directed. Inform your doctor if you take other medicines or have any other medical conditions or allergies.

Tell your doctor if you have or have ever had:

• diabetes;
• high blood pressure;
• a serious heart condition such as "AV block" (2nd or 3rd degree);
• a heart rhythm disorder;
• low blood pressure, if you are dehydrated; or
• liver disease.

It is not known if Precedex will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

If you are breastfeeding, tell your doctor if you notice irritability in the nursing baby.

Get emergency medical help if you have signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.

Certain side effects may happen within the first 48 hours after receiving Precedex. Tell your medical caregivers right away if you have: weakness, confusion, feeling nervous or agitated, increased sweating, weight loss, stomach pain, diarrhea, constipation, craving salty foods, dizziness, feeling light-headed, and headache.

Precedex may cause serious side effects. Call your doctor immediately if you have:

• fever with shortness of breath or rapid breathing.

Common side effects of Precedex may include:

• slow heartbeats;
• low blood pressure;
• dry mouth; or
• nausea, vomiting, and agitation.

Some side effects are more common in children receiving Precedex such as slow breathing and high blood pressure.

This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Precedex is injected into a vein by a healthcare provider.

Your breathing, heart rate, blood pressure, oxygen levels, and other vital signs will be watched closely during and after receiving Precedex.

In a medical setting, you are unlikely to miss a dose.

In a medical setting, an overdose will be treated quickly.

Follow your doctor's instructions regarding any restrictions on food, beverages, or activity.

Using Precedex with other drugs that cause drowsiness can increase this effect. Consult your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Other drugs may interact with Precedex, including prescription and over-the-counter medicines, vitamins, and herbal products. Inform your doctor about all other medicines you are using.