Proxacol (Topical application)

Hydrogen peroxide is used to treat raised seborrheic keratoses (waxy and scaly, raised areas of skin).

This medicine should be given only by your doctor or under their direct supervision.

Your doctor will watch your progress closely while you are using this medicine. This will help your doctor see if the medicine is working as it should and check for any side effects.

If your condition does not get better within 3 weeks, or if it gets worse, talk to your doctor.

Using Eskata™ can lead to serious eye issues, including blindness. If it accidentally gets in your eyes while you are using it, your doctor will tell you to rinse your eyes well with water for 15 to 30 minutes.

The treated area may become red, and you might experience swelling and scaling. Your doctor may wait for your skin to heal before continuing your treatment.

In deciding to use a medicine, you need to consider the risks of taking it compared to the benefits it may provide. This is a decision you and your doctor will make together. For this medicine, keep the following points in mind:

Allergies

Inform your doctor if you have ever experienced any unusual or allergic reactions to this medicine or any other medicines. Also, let your healthcare professional know about any other allergies you may have, including allergies to foods, dyes, preservatives, or animals. For over-the-counter products, read the label or package ingredients carefully.

Pediatric

Eskata™ is not meant for use in children.

Geriatric

Current studies have not shown any specific problems in elderly patients that would limit the effectiveness of Eskata™ in older adults.

Breast Feeding

There are no sufficient studies in women to determine the risk to infants when using this medication while breastfeeding. Consider the possible benefits and risks before using this medication during breastfeeding.

Interactions with Medicines

Some medicines should not be taken together at all, while in other situations, two different medicines may be used at the same time, even if there may be an interaction. In these cases, your doctor may adjust the dose or take other precautions. Inform your healthcare professional if you are taking any other prescription or over-the-counter (OTC) medicines.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used around the time of eating, or with specific types of food, due to potential interactions. Using alcohol or tobacco with some medicines may also lead to interactions. Talk to your healthcare professional about using your medicine with food, alcohol, or tobacco.

Along with its necessary effects, a medicine may cause some unwanted effects. Not all of these side effects may happen, but if they do, they may need medical attention.

Check with your doctor or nurse right away if any of the following side effects occur:

More common

• Redness, blistering, peeling, or loosening of the skin
• Skin burning, itching, pain, rash, stinging, or swelling skin ulcers

Less common

• Cracking or scarring of the skin
• Thinning, weakness, or wasting away of the skin

Rare

• Eyelid swelling
• Painful blisters on the trunk of the body

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Your health care professional may also be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue, are bothersome, or if you have any questions about them:

More common

• Darkening of the skin
• Dryness, peeling, or crusting of the skin
• Lightening of normal skin color
• Lightening of the treated areas of dark skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Aplicare One Hydrogen Peroxide
• Eskata
• Proxacol

In Canada

• Hydrogen Peroxide
• Hydrogen Peroxide Topical Solution 3%
• Hydrogen Peroxide Topical Solution 6%

Available Dosage Forms:

• Spray
• Gel/Jelly
• Solution
• Pad

Therapeutic Class: Disinfectant

You will receive this medicine in a clinic or doctor's office. A nurse or other trained health professional will give you the medicine using an applicator.

This medicine comes with a patient information leaflet. Read and follow these instructions carefully. Ask your doctor if you have any questions.

This medicine is applied directly on your lesions. Do not get any of the medicine in your eyes, nose, mouth, or ears. Rinse it off right away if it does get on these areas.

Your doctor may want to retreat you with Eskata™ after at least 3 weeks if your skin condition did not completely resolve.