Pseudoephedrine and triprolidine

Pseudoephedrine and triprolidine is a combination medicine that works as an antihistamine and a decongestant. It is used to treat a runny or stuffy nose, sneezing, itching, watery eyes, and sinus congestion caused by allergies or the common cold.

Pseudoephedrine and triprolidine may also be used for reasons not mentioned in this medication guide.

Use exactly as directed on the label, or as prescribed by your doctor. Cold or cough medicine is only for short-term use until your symptoms clear up.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Always follow directions on the medicine label about giving cough or cold medicine to a child. Do not use the medicine only to make a child sleepy. Death can occur from the misuse of cough or cold medicines in very young children.

Call your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken this medicine within the past few days.

Store at room temperature away from moisture and heat.

Do not use this medicine to make a child sleepy. Misusing this medicine may cause death in very young children.

You should not use pseudoephedrine and triprolidine if you are allergic to pseudoephedrine or triprolidine.

Do not use pseudoephedrine and triprolidine if you have taken an MAO inhibitor in the last 14 days. A dangerous drug interaction could happen. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.

Ask a doctor or pharmacist if this medicine is safe for you to use if you have ever had:

• asthma or another breathing problem such as emphysema or chronic bronchitis;
• high blood pressure, heart disease;
• glaucoma;
• diabetes; or
• a thyroid problem.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

pseudoephedrine and triprolidine may cause serious side effects. Stop using pseudoephedrine and triprolidine and call your doctor right away if you have:

• severe dizziness;
• nervousness;
• trouble sleeping; or
• high blood pressure (severe headache, pounding in your neck or ears).

Common side effects of pseudoephedrine and triprolidine may include:

• dizziness, drowsiness;
• dry mouth, nose, or throat;
• constipation;
• blurred vision; or
• feeling restless or excited (especially in children).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Usual Adult Dose for Allergic Rhinitis:

Pseudoephedrine 60 mg/ triprolidine 2.5 mg per tablet: 1 tablet orally every 4 to 6 hoursMaximum dose: 4 tablets per 24 hoursPseudoephedrine 30 mg/ triprolidine 1.25 mg per 5 mL: 10 mL orally every 6 hours

Usual Adult Dose for Cold Symptoms:

Pseudoephedrine 60 mg/ triprolidine 2.5 mg per tablet: 1 tablet orally every 4 to 6 hoursMaximum dose: 4 tablets per 24 hoursPseudoephedrine 30 mg/ triprolidine 1.25 mg per 5 mL: 10 mL orally every 6 hours

Usual Pediatric Dose for Allergic Rhinitis:

Pseudoephedrine 60 mg/ triprolidine 2.5 mg per tablet:12 years and older: 1 tablet orally every 4 to 6 hoursMaximum dose: 4 tablets per 24 hoursPseudoephedrine 30 mg/ triprolidine 1.25 mg per 5 mL:12 years and older: 10 mL orally every 6 hours

Usual Pediatric Dose for Cold Symptoms:

Pseudoephedrine 60 mg/ triprolidine 2.5 mg per tablet:12 years and older: 1 tablet orally every 4 to 6 hoursMaximum dose: 4 tablets per 24 hoursPseudoephedrine 30 mg/ triprolidine 1.25 mg per 5 mL:12 years and older: 10 mL orally every 6 hours

Since pseudoephedrine and triprolidine is taken as needed, you may not have a regular dosing schedule. If you miss a dose and it's almost time for your next one, just skip the missed dose. Do not take two doses at the same time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

• Avoid driving or doing anything dangerous until you understand how pseudoephedrine and triprolidine will affect you. Your reactions might be slower.

• Ask a doctor or pharmacist before using other cough or cold medicines that may have similar ingredients.

• Drinking alcohol can make some side effects of triprolidine worse.

Ask a doctor or pharmacist before using any other medicines that can make you sleepy, like opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures. Not all possible interactions are included here.