Pulmolite (Intravenous)

Technetium Tc 99m albumin aggregated injection is used to help your doctor create an image of your lungs to evaluate lung problems in both children and adults. It is also used to help your doctor see an image of your peritoneovenous [LeVeen] shunt.

Technetium Tc 99m albumin aggregated injection is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents that can be used to identify and treat certain diseases or to examine how the body's organs function.

This medicine should only be given by or under the direct supervision of a doctor who has specialized training in nuclear medicine.

It is very important for your doctor to monitor you or your child closely while receiving this medicine. This will help your doctor see if the medicine is working correctly and to determine if you or your child should keep using it.

This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and needs immediate medical attention. Contact your doctor right away if you have a rash, itching, swelling of the face, tongue, or throat, trouble breathing, or chest pain after receiving the injection.

You will be exposed to radiation when you receive this medicine. Discuss any concerns you have with your doctor.

In deciding to use a diagnostic test, any risks of the test must be weighed against the benefits it will provide. This decision will be made by you and your doctor. Additionally, other factors may affect test results. For this test, consider the following:

Allergies

Inform your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also, let your healthcare professional know if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, carefully read the label or package ingredients.

Pediatric

Studies conducted so far have not shown any specific problems in children that would limit the usefulness of Technetium Tc 99m albumin aggregated injection.

Geriatric

Studies have not been conducted on how age affects the use of technetium Tc 99m albumin aggregated injection in older patients. However, elderly patients are more likely to have age-related problems with the liver, kidneys, or heart, which may require caution when using this medicine.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication during breastfeeding. Consider the potential benefits and risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should not be used together at all, while in other cases, two different medicines may be used together even if an interaction might happen. In these situations, your doctor may want to adjust the dose or take other precautions. Inform your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicines.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be taken around the time of eating food or certain types of food, as interactions may occur. Using alcohol or tobacco with certain medicines may also lead to interactions. Discuss with your healthcare professional about using your medicine with food, alcohol, or tobacco.

Other Medical Problems

Having other medical conditions may affect the use of this diagnostic test. Be sure to tell your doctor if you have any other medical problems, especially:

• Allergy to human serum albumin, history of or
• Pulmonary hypertension (high blood pressure in the lungs), severe—Should not be used in patients with these conditions.

• Blood circulation problems or
• Cor pulmonale (serious heart condition) or
• Heart problems (e.g., right-to-left heart shunts)—Use with caution. May worsen these conditions.

Along with its necessary effects, a medicine may cause some unwanted effects. Not all of these side effects may happen, but if they do, they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

• Chest pain or tightness
• confusion
• cough
• difficulty swallowing
• dizziness
• faintness
• fast heartbeat
• fever and chills
• hives, itching, skin rash
• hoarseness
• irritation
• joint pain, stiffness, or swelling
• nausea
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• redness of the skin
• sweating
• swelling of the eyelids, face, lips, hands, or feet
• trouble breathing or swallowing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Your health care professional may also be able to tell you how to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome, or if you have any questions about them:

Incidence not known

• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• MPI MAA
• Pulmolite
• Technescan MAA

Available Dosage Forms:

• Kit

Therapeutic Class: Diagnostic Agent, Radiopharmaceutical Imaging

A doctor or other trained health professional will give you or your child this medicine. This medicine is given through a needle placed in one of your veins before you have a scan.

You will need to urinate right away after your exam and as often as you can for the first hours after you receive this medicine. Drink plenty of fluids before and after you receive this medicine so you will pass more urine. This will help flush the medicine from your body.