Pyridoxine

Pyridoxine is vitamin B6. Vitamins are found naturally in foods like meat, poultry, nuts, whole grains, bananas, and avocados. Vitamin B6 is essential for many functions in the body.

Pyridoxine is used to treat or prevent vitamin B6 deficiency. It is also used to treat a specific type of anemia (lack of red blood cells). Pyridoxine injection is also used to treat some types of seizures in babies.

Pyridoxine taken by mouth (oral) can be obtained without a prescription. Injectable pyridoxine must be administered by a healthcare professional.

Pyridoxine may also be used for purposes not mentioned in this medication guide.

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Pyridoxine tablets are taken by mouth. Injectable pyridoxine is injected into a muscle or into a vein through an IV. You may be shown how to use injections at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of needles, IV tubing, and other items used.

The recommended dietary allowance of pyridoxine increases with age. Follow your healthcare provider's instructions. You may also consult the Office of Dietary Supplements of the National Institutes of Health, or the U.S. Department of Agriculture (USDA) Nutrient Database (formerly "Recommended Daily Allowances") listings for more information.

Pyridoxine may be only part of a complete program of treatment that also includes a special diet. Follow the diet plan created for you by your doctor or nutrition counselor. Get familiar with the list of foods you should eat or avoid to help control your condition.

Store at room temperature away from moisture and heat.

Follow all instructions on your medicine label and package. Inform each of your healthcare providers about all your medical conditions, allergies, and all medicines you take.

You should not use pyridoxine if you have ever had an allergic reaction to it.

Ask a doctor or pharmacist if it is safe for you to use this medicine if:

• you have any other medical conditions;
• you take other medications or herbal products; or
• you are allergic to any drugs or foods.

To make sure you can safely receive injectable pyridoxine, tell your doctor if you have heart disease or kidney disease.

Ask a doctor before using this medicine if you are pregnant or breast-feeding. Your dose needs may be different. High doses of pyridoxine can harm a nursing baby.

Do not give this medicine to a child without medical advice.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Pyridoxine may cause serious side effects. Call your doctor right away if you experience:

• decreased sensation to touch, temperature, and vibration;
• loss of balance or coordination;
• numbness in your feet or around your mouth;
• clumsiness in your hands; or
• feeling tired.

Common side effects of pyridoxine may include:

• nausea;
• headache;
• drowsiness; or
• mild numbness or tingling.

This is not a complete list of side effects and others may happen. Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

Usual Adult Dose for Drug Induced Vitamin/Mineral Deficiency:

Isoniazid induced deficiencies: 100 mg intramuscularly or intravenously once a day followed by a 30 mg maintenance dose dailyPoisoning caused by ingestion of over 10 grams of isoniazid: Give an equal amount of pyridoxine, starting with 4 grams intravenously followed by 1 gram intramuscularly every 30 minutes

Usual Adult Dose for Dietary Supplement:

Injectable: Dietary deficiency: 10 to 20 mg intramuscularly or intravenously once a day for 3 weeks-Follow up with an oral multivitamin containing 2 to 5 mg pyridoxine daily for several weeks.-Correct poor dietary habits; prescribe a well balanced diet.Recommended dietary allowance of vitamin B6:18 years, male: 1.3 mg/day18 years, female: 1.2 mg/day19 to 50 years (both genders): 1.3 mg/day51 to 70 years, male: 1.7 mg/day51 to 70 years, female: 1.5 mg/dayPregnancy: 1.9 mg/dayLactation: 2 mg/day

Usual Adult Dose for Seizures:

Injectable: Vitamin B6 dependency syndrome: Up to 600 mg intramuscularly or intravenously daily, with a daily intake of 30 mg for life

Usual Pediatric Dose for Dietary Supplement:

Adequate intake of vitamin B6:0 to 6 months: 0.1 mg/day7 to 12 months: 0.3 mg/dayEstimated adequate intake of vitamin B6:1 to 3 years: 0.4 mg/day4 to 8 years: 0.5 mg/day9 to 13 years: 0.8 mg/day14 to 18 years, male: 1.1 mg/day14 to 18 years, female: 1 mg/dayRecommended dietary allowance of vitamin B6:1 to 3 years: 0.5 mg/day4 to 8 years: 0.6 mg/day9 to 13 years: 1 mg/day14 to 18 years, male: 1.3 mg/day14 to 18 years, female: 1.2 mg/day

Use the missed dose as soon as you remember. Skip the missed dose if it is nearly time for your next scheduled dose. Do not use extra medicine to compensate for the missed dose.

Seek emergency medical help or call the Poison Help line at 1-800-222-1222.

Follow your doctor's advice regarding any limits on food, drinks, or activities.

Other drugs may interact with pyridoxine, including prescription and over-the-counter medicines, vitamins, and herbal products. Inform all of your health care providers about all medicines you are currently using and any medicine you begin or stop using.