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Quenalog (Topical)

Generic name: nystatin and triamcinolone

Brand names: Mycolog-II, Mytrex, Quenalog

Last updated October 27, 2025 0 views
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Uses for Quenalog

Nystatin and triamcinolone combination includes an antifungal and a corticosteroid (cortisone-like medicine).

Antifungals are used to treat infections caused by fungi. They work by killing the fungus or stopping it from growing. This medicine will not work for other types of infections. Corticosteroids are part of a group of medicines called steroids. They help relieve redness, swelling, itching, and other discomfort from many skin issues.

This medicine is used to treat certain fungal infections, like Candida (Monilia), and to help relieve the discomfort caused by the infection.

Topical corticosteroids may rarely cause some serious side effects. Some side effects may be more likely to happen in children. Before using this medicine in children, talk to your doctor about these risks and the benefits this medicine may provide.

Nystatin and triamcinolone combination is available only with your doctor's prescription.

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Precautions while using Quenalog

To fully clear your infection and help prevent it from coming back, it's important to maintain good health habits. Keep the affected area as cool and dry as possible.

If your skin problem does not get better within 2 or 3 weeks, or if it worsens, contact your doctor.

The corticosteroid in this medicine may be absorbed through the skin and could be more likely to cause side effects in children. Long-term use may also impact growth and development. Children using this medicine should be monitored closely by their doctor.

For diabetic patients:

  • Although it is rare, the corticosteroid in this medicine may raise blood and urine sugar levels, particularly if you have severe diabetes and are using large amounts of this medicine. Talk to your doctor before making any changes to your diet or the dosage of your diabetes medicine.

This section was rewritten for readability and reviewed for meaning.

Before using Quenalog

In deciding to use a medicine, it's important to consider the risks against the benefits. This decision should be made with your doctor. For this medicine, please consider the following:

Allergies

Inform your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also, let your healthcare professional know if you have any other allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, carefully read the label or package ingredients.

Pediatric

Children may be more sensitive to the effects of topical nystatin and triamcinolone combination. This could increase the chance of side effects during treatment. Therefore, it is especially important to discuss with your child's doctor the benefits and risks of using this medicine.

Geriatric

Many medicines have not been studied specifically in older adults. Therefore, it may not be known if they work the same way as they do in younger adults. Although there is no specific information comparing the use of topical nystatin and triamcinolone combination in older adults to other age groups, this medicine is not expected to cause different side effects or problems in older adults than in younger adults.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication while breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should not be used together at all, while in other cases, two different medicines may be used together even if there is a possibility of an interaction. In these situations, your doctor may adjust the dose, or other precautions may be necessary. When taking this medicine, it is particularly important for your healthcare professional to know if you are taking any of the medicines listed below. The following interactions are based on their potential significance and may not include all possibilities.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Desmopressin
  • Rotavirus Vaccine, Live

Using this medicine with any of the following medicines is usually not recommended, but may be necessary in some cases. If both medicines are prescribed together, your doctor may adjust the dose or frequency for one or both medicines.

  • Aldesleukin
  • Aspirin
  • Atazanavir
  • Balofloxacin
  • Bemiparin
  • Besifloxacin
  • Ceritinib
  • Ciprofloxacin
  • Cobicistat
  • Darunavir
  • Enoxacin
  • Fleroxacin
  • Flumequine
  • Gatifloxacin
  • Gemifloxacin
  • Levofloxacin
  • Lomefloxacin
  • Lutetium Lu 177 Dotatate
  • Macimorelin
  • Moxifloxacin
  • Nadifloxacin
  • Nadroparin
  • Nirmatrelvir
  • Norfloxacin
  • Ofloxacin
  • Pazufloxacin
  • Pefloxacin
  • Prulifloxacin
  • Ritonavir
  • Rufloxacin
  • Sargramostim
  • Somatrogon-ghla
  • Sparfloxacin
  • Tosufloxacin

Using this medicine with any of the following medicines may increase the risk of certain side effects, but using both may still be the best treatment for you. If both medicines are prescribed together, your doctor may adjust the dose or frequency for one or both medicines.

  • Alcuronium
  • Atracurium
  • Auranofin
  • Fosphenytoin
  • Gallamine
  • Hexafluorenium
  • Licorice
  • Metocurine
  • Phenytoin
  • Primidone
  • Saiboku-To

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around mealtime or with certain types of food due to possible interactions. Using alcohol or tobacco with certain medicines may also cause interactions. Discuss the use of your medicine with food, alcohol, or tobacco with your healthcare professional.

Other Medical Problems

Other medical problems may affect the use of this medicine. Be sure to inform your doctor if you have any other medical issues, especially:

  • Herpes
  • Vaccinia (cowpox)
  • Varicella (chickenpox)
  • Other virus infections of the skin—Triamcinolone may speed up the spread of virus infections
  • Tuberculosis (TB) of the skin—Triamcinolone may worsen a TB infection

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Side Effects of Quenalog

Along with its necessary effects, a medicine can also cause some unwanted effects. Not all of these side effects may happen, but if they do, they might need medical attention.

Check with your doctor right away if any of the following side effects happen:

Rare

  • Blistering, burning, dryness, itching, peeling, or any other signs of irritation not present before using this medicine

Check with your doctor as soon as possible if any of the following side effects happen:

Many of the side effects listed above are more likely to occur in children, who may absorb larger amounts of this medicine.

  • Acne or oily skin
  • Increased hair growth, especially on the face
  • Increased hair loss, especially on the scalp
  • Reddish purple lines on arms, face, legs, trunk, or groin
  • Thinning of skin with easy bruising

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

  • Mycolog-II
  • Mytrex
  • Quenalog

Available Dosage Forms:

  • Cream
  • Ointment

Therapeutic Class: Anti-Infective/Anti-Inflammatory Combination

Pharmacologic Class: Triamcinolone

Chemical Class: Polyene

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Proper use of Quenalog

Do not use this medicine in or around the eyes.

Check with your doctor before using this medicine on any other skin problems. It should not be used on bacterial or virus infections. Also, it should only be used on certain fungus infections of the skin.

Apply a thin layer of this medicine to the affected area and rub in gently and thoroughly.

The use of any kind of airtight covering over this medicine may increase absorption of the medicine and the chance of irritation and other side effects. Therefore, do not bandage, wrap, or apply any airtight covering or other occlusive dressing (for example, kitchen plastic wrap) over this medicine unless directed to do so by your doctor. Also, wear loose-fitting clothing when using this medicine on the groin area. When using this medicine on the diaper area of children, avoid tight-fitting diapers and plastic pants.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if your symptoms have disappeared. Do not miss any doses. However, do not use this medicine more often or for a longer time than your doctor ordered. To do so may increase absorption through your skin and the chance of side effects. In addition, too much use, especially on thin skin areas (for example, face, armpits, groin), may result in thinning of the skin and stretch marks.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For fungus infections: For cream dosage form: Adults and children—Apply to the affected area(s) of the skin two times a day, morning and evening For ointment dosage form: Adults and children—Apply to the affected area(s) of the skin two or three times a day.

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Frequently asked questions

  • Is triamcinolone acetonide an antifungal cream?

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Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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