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Refresh Plus

Generic name: ocular lubricant

Brand names: Advanced Eye Relief Dry Eye, Artelac Nighttime, Artificial Tears, Bion Tears, Blink Contacts, Blink Gel Tears, Blink Tears, Clear Eyes CLR, Clear Eyes Tears, Dry Eye Relief, FreshKote Preservative Free, GenTeal, GenTeal Mild, GenTeal PF Tears Moderate, GenTeal Tears Moderate, GenTeal Tears Night-Time, GenTeal Tears Severe, Hypotears, ImproVue, Isopto Tears

Last updated November 3, 2026 0 views
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What is Refresh Plus?

There are many brands and types of ocular lubricant available, and not all of them are included in this leaflet.

Refresh Plus is used in adults to help relieve burning, irritation, and discomfort from dry eyes.

Refresh Plus may also be used for reasons not mentioned in this medication guide.

This section was rewritten for readability and reviewed for meaning.

How should I use Refresh Plus?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Wash your hands before using Refresh Plus.

Do not use Refresh Plus and call your pharmacist if the medicine looks cloudy or has changed color.

Do not touch the tip of the eye dropper or ointment tube or place it directly on your eye. A contaminated tip can infect your eye, which could lead to serious vision problems.

Call your doctor if your symptoms do not improve, or if they get worse while using Refresh Plus.

Store at room temperature away from moisture and heat.

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Warnings

You should not use Refresh Plus to treat or prevent an eye infection.

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Before taking this medicine

You should not use Refresh Plus if you are allergic to it. This medicine will not treat or prevent an eye infection.

Ask a doctor or pharmacist if it is safe for you to use Refresh Plus if you have any type of infection in your eye.

Tell your doctor if you are pregnant or breastfeeding.

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Refresh Plus side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using Refresh Plus and call your doctor if you have:

  • severe burning, stinging, or eye irritation after using the medicine;
  • eye pain; or
  • changes in your vision.

Common side effects of Refresh Plus may include:

  • mild burning or irritation in your eyes;
  • itching or redness in your eyes;
  • watery eyes;
  • blurred vision; or
  • sensitivity to light.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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What happens if I miss a dose?

Refresh Plus is used as needed. If you have a dosing schedule and miss a dose, skip that dose. Do not use two doses at the same time.

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What happens if I overdose?

An overdose of ocular lubricant is not expected to be dangerous. Seek emergency medical help or call the Poison Help line at 1-800-222-1222 if someone accidentally swallows the medication.

Refresh Plus may cause blurred vision. Avoid driving or doing anything dangerous until you know how this medicine affects you.

Do not use other eye medications unless your doctor instructs you to.

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What other drugs will affect Refresh Plus?

Medicine used in the eyes is not likely to be influenced by other drugs you take. However, many drugs can interact with each other. Inform your doctor about all the medicines you are currently using, including prescription and over-the-counter medicines, vitamins, and herbal products.

This section was rewritten for readability and reviewed for meaning.

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.