Rezipres (Intravenous)

Ephedrine injection is used to treat hypotension (low blood pressure) caused by anesthesia (numbing medicines).

This medicine is to be given only by your doctor or under their direct supervision.

Your doctor will monitor your progress closely while you are getting this medicine. This will help your doctor determine if the medicine is working correctly and check for any side effects.

Hypertension (high blood pressure) may happen after receiving this medicine. It is very important that your doctor checks your blood pressure after you receive this medicine. If you notice any changes in your usual blood pressure, call your doctor immediately.

Using this medicine repeatedly may lead to a quick decrease in how well the drug works.

Do not take other medicines unless your doctor has discussed them with you. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

In deciding to use a medicine, the risks of taking the medicine must be weighed against the benefits it will provide. This is a decision you and your doctor will make together. For this medicine, the following points should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also inform your healthcare professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies have not been done on the effects of ephedrine injection in children. Safety and effectiveness have not been established.

Geriatric

Studies conducted so far have not shown any specific problems in elderly patients that would limit the usefulness of ephedrine injection. However, older patients are more likely to have kidney, liver, or heart issues, which may require caution and a dose adjustment for patients receiving this medicine.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication while breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should not be used together at all, while in other situations, two different medicines may be used together even if an interaction could occur. In these cases, your doctor may want to change the dose or take other precautions. When you are receiving this medicine, it is very important that your healthcare professional knows if you are taking any of the medicines listed below. The following interactions are based on their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Dihydroergotamine
• Isocarboxazid
• Rasagiline
• Selegiline
• Tranylcypromine

Using this medicine with any of the following medicines is usually not recommended, but may be needed in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acetyldigoxin
• Deslanoside
• Digitalis
• Digitoxin
• Digoxin
• Dinoprostone
• Ergonovine
• Iobenguane I 123
• Iobenguane I 131
• Iproniazid
• Methylergonovine
• Metildigoxin
• Midodrine
• Oxytocin
• Pargyline
• Urea
• Zavegepant

Interactions with Food/Tobacco/Alcohol

Some medicines should not be taken around the time of eating food or certain types of food due to possible interactions. Using alcohol or tobacco with certain medicines may also lead to interactions. The following interactions are based on their potential significance and are not necessarily all-inclusive.

Other Medical Problems

Having other medical problems may affect the use of this medicine. Make sure to tell your doctor if you have any other medical issues, especially:

• Heart disease or
• Hypertension (high blood pressure) or
• Stroke, or history of—Use with caution. May worsen these conditions.

• Kidney disease—Use with caution. The effects may be increased because the medicine is removed from the body more slowly.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do happen, they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

• Blurred vision
• chest pain or discomfort
• dizziness
• fast, pounding, or irregular heartbeat or pulse
• headache
• lightheadedness, dizziness, or fainting
• nervousness
• pounding in the ears
• slow or fast heartbeat
• trouble breathing
• unusual tiredness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

• Nausea or vomiting
• restlessness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Akovaz
• Corphedra
• Rezipres

Available Dosage Forms:

• Solution

Therapeutic Class: Vasopressor

Pharmacologic Class: Adrenergic System

Chemical Class: Alkylarylamine

A doctor or other trained health professional will give you this medicine. This medicine is given through a needle placed in your veins.