Rid One and Done

Ivermectin lotion is used to treat head lice in adults and children who are at least 6 months old.

Ivermectin cream is used to treat the inflammatory skin lesions caused by rosacea.

Rid One and Done may also be used for reasons not mentioned in this medication guide.

Stop using Rid One and Done and call your doctor if you get a rash, eye irritation, or a skin or scalp infection, or if skin or scalp irritation does not go away.

Tell your doctor if you have or have ever had:

• any allergies; or
• skin conditions or sensitivities.

It is not known if Rid One and Done will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using Rid One and Done.

If you breastfeed, avoid getting this medicine on your breast to prevent contact with your baby.

Do not use ivermectin lotion on a child younger than 6 months old. An adult should supervise use of the lotion in children 6 months to younger than 12 years. Do not use Rid One and Done on a child without medical advice.

Get emergency medical help if you have signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.

Rid One and Done may cause serious side effects. Stop using Rid One and Done and call your doctor right away if you have:

• any skin rash, no matter how mild;
• eye irritation;
• skin or scalp irritation that does not go away;
• a skin or scalp infection; or
• trouble breathing.

Common side effects of Rid One and Done may include:

• skin burning or skin irritation;
• dandruff or dry skin; or
• eye redness, soreness, or irritation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Use exactly as directed on the label, or as prescribed by your doctor. Read all medication guides or instruction sheets.

Wash your hands before and after applying this medicine.

To use ivermectin cream:

• Apply once a day, use a pea-sized amount for each affected facial area (forehead, chin, nose, and each cheek). Spread evenly in a thin layer.

To use ivermectin lotion:

• Use only enough lotion, up to 1 tube, to completely cover dry hair and scalp. Cover the scalp first, then coat every hair from root to tip.
• After fully covering your hair and scalp, leave lotion on for 10 minutes using a timer or clock. Rinse completely with water only.
• Wait 24 hours before using shampoo.
• Use the lotion only once. Do not use it again on the same person for the same lice infestation without talking to a healthcare provider.
• Throw away after one use, even if medicine remains.
• Have another person check everyone in your household for lice or eggs. Recheck everyone for lice 1 week after treatment. Treat anyone affected as directed. Machine-wash bedding and clothing used by anyone with lice at 150°F, then dry them in a hot dryer for 20 minutes.

Call your doctor if your symptoms do not improve, or if they get worse.

Do not cover treated skin with a bandage unless your doctor tells you to.

Store at room temperature away from moisture and heat. Do not freeze ivermectin lotion.

If you miss a dose of ivermectin topical, use the medicine as soon as you remember, but skip the missed dose if it is almost time for your next dose. Do not use two doses at the same time.

Ivermectin lotion is used as a single dose and does not require a daily dosing schedule.

Seek emergency medical help or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medicine.

Do not let Rid One and Done get in your eyes or mouth, on your lips, or inside your nose, ears, or vagina. If it gets in your eyes, gently rinse with water.

When using the lotion, keep your eyes tightly closed and cover them with a washcloth or towel. Do not use this medicine to treat head lice in your eyebrows or eyelashes; see a doctor instead.

Medicine used on the skin is not likely to be affected by other drugs you use, but many drugs can interact. Tell your doctor about all your current medicines, including prescription and over-the-counter medicines, vitamins, and herbal products.