Ropivacaine

Ropivacaine is used as a local anesthesia for a spinal block, also known as an epidural. This medication helps to numb an area during surgery or a C-section, or to reduce pain during labor.

Ropivacaine may also be used for reasons not mentioned in this medication guide.

Tell your caregivers right away if you have a serious side effect such as: confusion, trouble with speech or vision, ringing in your ears, numbness or tingling around your mouth, gasping, feeling unusually hot, skin that is pale, gray, or blue, headache, rapid heart rate, shortness of breath, or feeling like you might faint.

You should not use ropivacaine if you are allergic to it or to any type of numbing medicine.

A serious blood issue called methemoglobinemia may happen while using ropivacaine. Your risk may be higher if you have glucose-6-phosphate dehydrogenase (G6PD) deficiency, heart problems, or lung problems. Your risk may also be increased while taking certain medications and if your child is younger than 6 months.

Tell your doctor if you have ever had:

• a serious blood issue called methemoglobinemia;
• liver or kidney disease; or
• heart disease.

It is not known if ropivacaine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using ropivacaine.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

• a severe blood problem called methemoglobinemia -- pale, gray, or blue colored skin, headache, rapid heart rate, shortness of breath, feeling lightheaded, or tired;
• feelings of anxiety, restlessness, confusion, or feeling like you might faint;
• problems with speech or vision;
• ringing in the ears, metallic taste, numbness or tingling around your mouth, or tremors;
• seizures;
• weak or shallow breathing;
• slow heart rate, weak pulse; or
• fast heart rate, gasping, feeling unusually hot.

Common side effects include:

• feeling like you might faint;
• nausea, vomiting;
• slow heart rate;
• headache;
• back pain;
• fever;
• pain;
• itching;
• numbness, tingling, burning pain; or
• pale skin, tiredness, feeling light-headed or short of breath, cold hands and feet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Ropivacaine is given as an injection through a needle placed into an area of your middle or lower back near your spine. You will receive this injection in a hospital or surgical setting.

Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely while you are receiving ropivacaine.

Some numbing medications can have long-lasting or delayed effects. Talk to your doctor if you have concerns about this risk. Call your doctor if you have joint pain or stiffness, or weakness in any part of your body that occurs after your surgery, even months later.

Since ropivacaine is given as needed before a surgery or other medical procedure, you will not likely have a regular dosing schedule.

Tell your caregivers immediately if you think you have received too much ropivacaine.

Ropivacaine can make a large area of your body numb. Be careful to avoid injuries until the feeling comes back completely.

Tell your doctor about all your other medicines, especially:

• other anesthetics--articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine;
• heart medications--nitric oxide, nitroglycerin, nitroprusside, nitrous oxide;
• cancer medications--cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase;
• antibiotics--dapsone, nitrofurantoin, sulfonamides;
• drugs for malaria--chloroquine, primaquine;
• drugs for epilepsy--phenobarbital, phenytoin, valproate; or
• other drugs--acetaminophen, metoclopramide, quinine, sulfasalazine.

This list is not complete and many other drugs may affect ropivacaine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.