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Sodium chloride (oral)

Generic name: sodium chloride (oral)

Last updated November 3, 2026 0 views
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What is sodium chloride?

Sodium chloride is the chemical name for salt. Sodium is an electrolyte that helps control the amount of water in your body. Sodium also helps with nerve signals and muscle movements.

Sodium chloride is used to treat or prevent sodium loss due to dehydration, excessive sweating, or other reasons.

Sodium chloride may also be used for reasons not mentioned in this medication guide.

This section was rewritten for readability and reviewed for meaning.

How should I take sodium chloride?

Take exactly as prescribed by your doctor. Do not take larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Take sodium chloride with a full glass (8 ounces) of water.

Sodium chloride may be taken with or without food.

To ensure this medication is helping your condition, your blood may need to be tested often. Visit your doctor regularly.

Do not share this medication with anyone else, even if they have the same symptoms you do.

Call your doctor if your symptoms do not improve, or if they get worse while using sodium chloride.

Store at room temperature away from moisture, heat, and light.

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Warnings

You should not take sodium chloride if you have ever had an allergic reaction to it, or if you have high sodium levels in your blood.

Before you take sodium chloride, tell your doctor if you have high blood pressure, kidney or liver disease, fluid retention (especially around your legs or your lungs), congestive heart failure, preeclampsia of pregnancy if you are on a low-salt diet, or if you are allergic to any foods or drugs.

Tell your doctor if you are pregnant or breast-feeding.

Stop using sodium chloride and call your doctor at once if you have stomach pain, nausea and vomiting, or swelling in your hands or feet.

Call your doctor if your symptoms do not improve, or if they get worse while using sodium chloride.

This section was rewritten for readability and reviewed for meaning.

Before taking this medicine

You should not take sodium chloride if you have ever had an allergic reaction to it, or if you have high sodium levels in your blood.

To make sure you can safely take sodium chloride, tell your doctor if you have any of these other conditions:

  • high blood pressure;
  • kidney disease;
  • liver disease (especially cirrhosis);
  • a buildup of fluid around your lungs (also called pleural effusion);
  • fluid retention (especially swelling in your ankles or feet);
  • congestive heart failure;
  • if you are pregnant and you have high blood pressure and fluid retention (also called preeclampsia);
  • if you are allergic to any foods or drugs; or
  • if you are on a low-salt diet.

FDA pregnancy category C. It is not known whether sodium chloride will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether sodium chloride passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

This section was rewritten for readability and reviewed for meaning.

Sodium chloride side effects

Get emergency medical help if you notice any of these signs of an allergic reaction: hives; trouble breathing; swelling of your face, lips, tongue, or throat.

Stop using sodium chloride and call your doctor right away if you experience a serious side effect like:

  • nausea and vomiting;
  • stomach pain; or
  • swelling in your hands, ankles, or feet.

Less serious side effects are more likely, and you might not experience any at all.

This is not a complete list of side effects, and others may happen. Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

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What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not take extra medicine to make up for the missed dose.

This section was rewritten for readability and reviewed for meaning.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, stomach cramps, diarrhea, fast or uneven heart rate, weakness, swelling in your hands or feet, feeling restless or irritable, slow breathing, feeling short of breath, or seizure (convulsions).

  • Avoid becoming overheated or dehydrated during exercise and in hot weather.
  • Follow your doctor's instructions about the type and amount of liquids you should drink.
  • In some cases, drinking too much liquid can be as unsafe as not drinking enough.

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What other drugs will affect sodium chloride?

There may be other drugs that can interact with sodium chloride. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Find detailed information on biosimilars for this medication.

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Common questions about sodium chloride

Does salt water help mouth ulcers?
Yes. Rinsing with warm salt water can help a mouth ulcer (canker sore) feel better and heal more comfortably. Salt water can ease pain and lower the chance that the sore gets infected, and it helps calm swelling around the sore. It is not a cure, though. Most mouth ulcers heal on their own in 1 to 2 weeks, with or without treatment. Continue reading

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Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.