SUMAtriptan Succinate Syringe (injection)

SUMAtriptan Succinate Syringe is a medicine for headaches that narrows blood vessels around the brain. It also reduces substances in the body that can cause headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.

SUMAtriptan Succinate Syringe is used to treat migraines and cluster headaches in adults. It will only treat a headache. SUMAtriptan Succinate Syringe will not prevent headaches or reduce the number of attacks.

SUMAtriptan Succinate Syringe should not be used to treat a common tension headache, or a headache that causes loss of movement on one side of your body. Use this medicine only if your doctor has confirmed that you have migraine headaches.

SUMAtriptan Succinate Syringe may also be used for purposes not listed in this medication guide.

You should not use SUMAtriptan Succinate Syringe if you have ever had heart disease, coronary artery disease, problems with blood circulation, Wolff-Parkinson-White syndrome, uncontrolled high blood pressure, severe liver disease, a heart attack or stroke, or if your headache feels different from your usual migraine headaches.

Do not use SUMAtriptan Succinate Syringe if you have taken an MAO inhibitor in the last 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Do not use SUMAtriptan Succinate Syringe within 24 hours before or after taking another migraine headache medicine.

You should not use SUMAtriptan Succinate Syringe if you are allergic to it, if you have a headache that feels different from your usual migraine headaches, or if you have ever had:

• heart problems, or a stroke (including "mini-stroke");
• coronary artery disease, angina (chest pain), blood circulation problems, or lack of blood supply to the heart;
• circulation problems affecting your legs, arms, stomach, intestines, or kidneys;
• a heart disorder called Wolff-Parkinson-White syndrome;
• uncontrolled high blood pressure; or
• severe liver disease.

Do not use SUMAtriptan Succinate Syringe if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could happen. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have ever had:

• liver or kidney disease;
• epilepsy or another seizure disorder;
• high blood pressure, a heart rhythm disorder; or
• risk factors for coronary artery disease (such as diabetes, menopause, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease, or being older than 40 and a man).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Sumatriptan can pass into breast milk. Do not breast-feed within 12 hours after using sumatriptan. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.

SUMAtriptan Succinate Syringe injection is not approved for use by anyone younger than 18 years old.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

SUMAtriptan Succinate Syringe may cause serious side effects. Stop using SUMAtriptan Succinate Syringe and call your doctor immediately if you have:

• sudden and severe stomach pain and bloody diarrhea;
• severe chest pain, shortness of breath, irregular heartbeats;
• a seizure (convulsions);
• blood circulation problems in your legs or feet--cramps, tight or heavy feeling, numbness or tingling, muscle weakness, burning pain, cold feeling, color changes (pale or blue), hip pain;
• heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
• high levels of serotonin in the body--agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting;
• increased blood pressure--severe headache, blurred vision, pounding in your neck or ears, anxiety, nosebleed; or
• signs of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance.

Common side effects of SUMAtriptan Succinate Syringe may include:

• numbness, tingling, warmth, redness, or burning sensation;
• pressure or heavy feeling in any part of your body;
• dizziness, drowsiness, feeling weak or tired;
• neck pain or stiffness; or
• pain or redness where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Use SUMAtriptan Succinate Syringe as soon as you notice headache symptoms. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Never use more than your recommended dose. Overuse of migraine headache medicine can make headaches worse. Tell your doctor if the medicine seems to stop working as well in treating your migraine attacks.

SUMAtriptan Succinate Syringe is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.

SUMAtriptan Succinate Syringe Succinate Syringe comes in a vial (bottle), a needle-free injector device, or a prefilled cartridge for an auto-injector syringe. Each type is for one use only.

Read and carefully follow any Instructions for Use provided with your medicine. Do not use SUMAtriptan Succinate Syringe if you don't understand all instructions for proper use. Ask your doctor or pharmacist if you have questions.

Prepare your injection only when you are ready to give it. Do not use a vial if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.

After an injection: If your headache does not completely go away, call your doctor before using a second injection. If your headache goes away and then comes back, use a second injection if it has been at least 1 hour since your first injection. Do not use more than 2 injections in 24 hours. Call your doctor if your symptoms do not improve.

Store at room temperature away from moisture, heat, and light. Throw away any unused medicine after the expiration date on the label has passed.

Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.

Since SUMAtriptan Succinate Syringe is used as needed, it does not have a daily dosing schedule. Call your doctor if your symptoms do not improve after using this medicine.

Seek emergency medical help or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include tremors, redness of the skin on your arms or legs, weakness, loss of coordination, trouble breathing, blue-colored lips or fingernails, vision problems, or a seizure (convulsions).

Do not use SUMAtriptan Succinate Syringe within 24 hours before or after using another migraine headache medicine, including:

• SUMAtriptan Succinate Syringe tablets or nasal spray, almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, zolmitriptan; or
• ergot medicine such as dihydroergotamine, ergotamine, ergonovine, or methylergonovine.

Avoid driving or doing anything dangerous until you know how SUMAtriptan Succinate Syringe will affect you. Your reactions could be impaired.

Using SUMAtriptan Succinate Syringe along with certain other medicines can lead to a dangerous increase in serotonin levels in your body, known as "serotonin syndrome," which can be life-threatening. Inform your doctor if you are also taking:

• medicine to treat depression or a psychiatric disorder;
• medicine for Parkinson's disease;
• medicine for serious infections;
• herbal products;
• stimulant medicine;
• opioid medicine; or
• medicine to prevent nausea and vomiting.

This list is not complete. Other medications, including prescription and over-the-counter medicines, vitamins, and herbal products, may also interact with SUMAtriptan Succinate Syringe. Not all possible drug interactions are mentioned here.