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Systane Preservative Free

Generic name: ocular lubricant

Brand names: Advanced Eye Relief Dry Eye, Artelac Nighttime, Artificial Tears, Bion Tears, Blink Contacts, Blink Gel Tears, Blink Tears, Clear Eyes CLR, Clear Eyes Tears, Dry Eye Relief, FreshKote Preservative Free, GenTeal, GenTeal Mild, GenTeal PF Tears Moderate, GenTeal Tears Moderate, GenTeal Tears Night-Time, GenTeal Tears Severe, Hypotears, ImproVue, Isopto Tears

Last updated November 3, 2026 0 views
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What is Systane Preservative Free?

There are many brands and types of ocular lubricant available, and not all are included in this leaflet.

Systane Preservative Free is used by adults to relieve burning, irritation, and discomfort caused by dry eyes.

Systane Preservative Free may also be used for reasons not mentioned in this medication guide.

This section was rewritten for readability and reviewed for meaning.

How should I use Systane Preservative Free?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Wash your hands before using Systane Preservative Free.

Do not use Systane Preservative Free and call your pharmacist if the medicine looks cloudy or has changed color.

Do not touch the tip of the eye dropper or ointment tube or place it directly on your eye. A contaminated tip can infect your eye, which could lead to serious vision problems.

Call your doctor if your symptoms do not improve, or if they get worse while using Systane Preservative Free.

Store at room temperature away from moisture and heat.

This section was rewritten for readability and reviewed for meaning.

Warnings

You should not use Systane Preservative Free to treat or prevent an eye infection.

This section was rewritten for readability and reviewed for meaning.

Before taking this medicine

You should not use Systane Preservative Free if you are allergic to it. This medicine will not treat or prevent an eye infection.

Ask a doctor or pharmacist if it is safe for you to use Systane Preservative Free if you have any type of infection in your eye.

Tell your doctor if you are pregnant or breastfeeding.

This section was rewritten for readability and reviewed for meaning.

Systane Preservative Free side effects

Get emergency medical help if you notice any signs of an allergic reaction: hives; trouble breathing; swelling of your face, lips, tongue, or throat.

Stop using Systane Preservative Free and contact your doctor if you experience:

  • severe burning, stinging, or irritation in your eyes after using the medicine;
  • eye pain; or
  • changes in your vision.

Common side effects of Systane Preservative Free may include:

  • mild burning or irritation in your eyes;
  • itching or redness of your eyes;
  • watery eyes;
  • blurred vision; or
  • sensitivity to light.

This is not a complete list of side effects, and other side effects may occur. Contact your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

This section was rewritten for readability and reviewed for meaning.

What happens if I miss a dose?

Systane Preservative Free can be used as needed. If you have a dosing schedule and miss a dose, just skip it. Do not use two doses at the same time.

This section was rewritten for readability and reviewed for meaning.

What happens if I overdose?

An overdose of ocular lubricant is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

Systane Preservative Free may cause blurred vision. Avoid driving or doing anything dangerous until you know how this medicine will affect you.

Do not use other eye medications unless your doctor tells you to.

This section was rewritten for readability and reviewed for meaning.

What other drugs will affect Systane Preservative Free?

Medicine used in the eyes is not likely to be influenced by other drugs you take. However, many drugs can interact with each other. Inform your doctor about all the medicines you are currently using, including prescription and over-the-counter medicines, vitamins, and herbal products.

This section was rewritten for readability and reviewed for meaning.

Common questions about Systane

What are the best eye drops for dry eyes?
Dry eyes are a common condition that can cause symptoms like stinging, burning, itching, redness, and a gritty sensation. These symptoms occur when your eyes don’t produce enough tears or when the quality of your tears is poor. Choosing the right eye drops depends on how severe your symptoms are, the underlying cause of your dry eye, and your individual needs. Continue reading
Can dry eyes cause blurry vision? Which medications help?
Yes, dry eyes can cause blurry or fluctuating vision. This occurs because dry eye syndrome disrupts the tear film that coats the eye’s surface, leading to uneven light refraction and irregularities on the corneal surface. Meibomian gland dysfunction, which affects the oily layer of the tear film, is a major contributor to this problem. Continue reading

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Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.