Tezspire Pre-filled Syringe

Tezspire Pre-filled Syringe is used along with other medicines to help manage severe asthma in adults and children who are at least 12 years old. This medicine is not a fast-acting rescue medicine for asthma attacks.

Tezspire Pre-filled Syringe is also used with other medicines to help control symptoms of chronic rhinosinusitis with nasal polyps (long-term sinus inflammation) in adults and children who are at least 12 years old.

Tezspire Pre-filled Syringe is prescribed after other treatments did not work or have stopped working.

Tezspire Pre-filled Syringe may also be used for purposes not mentioned in this medication guide.

Use only as directed. Inform your doctor if you are taking other medicines or have other medical conditions or allergies.

You should not use Tezspire Pre-filled Syringe if you are allergic to it.

Tell your doctor if you have or have ever had:

• a severe allergic reaction;
• an infection caused by a parasite (helminth); or
• if you are scheduled to receive or have received a live vaccine recently.

Make sure you are up to date on all vaccines before you start using Tezspire Pre-filled Syringe.

It is not known if Tezspire Pre-filled Syringe will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using Tezspire Pre-filled Syringe.

Get emergency medical help if you have signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.

Signs of a severe or life-threatening allergic reaction may happen right after the injection or even hours or days after using Tezspire Pre-filled Syringe. Your treatment may stop if you experience this side effect.

Common side effects of Tezspire Pre-filled Syringe may include:

• nosebleed;
• pain, bruising, swelling, or irritation at the injection site;
• flu or cold symptoms such as stuffy nose, sneezing, sore throat; or
• joint or back pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Tezspire Pre-filled Syringe is injected under the skin, usually once every 4 weeks. A healthcare provider will give you this injection when using the vial or the prefilled syringe.

A healthcare provider may teach you how to properly use the prefilled pen by yourself. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Prepare an injection only when you are ready to give it. Leave the needle cap on until you are ready to inject your dose. Call your pharmacist if the medicine looks cloudy, has changed colors or has particles in it.

Do not inject within 2 inches of your navel (belly button) or areas where the skin is tender, hard, scaly, damaged, bruised, or has scars. Do not inject into the same place two times in a row.

Throw away a prefilled pen after one use, even if there is still medicine left inside. Do not reuse a needle or pen. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.

Tezspire Pre-filled Syringe is not a fast-acting rescue medicine for asthma attacks. Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working.

Do not change or stop your other medicines, including corticosteroid medicines or other asthma medicines unless your healthcare provider tells you to.

Call your doctor if your symptoms do not improve, or if they get worse.

Store this medicine in the original container in the refrigerator. Protect from light and do not freeze or shake the medicine.

Take the medicine out of the refrigerator and let it reach room temperature for 60 minutes before injecting your dose. Do not warm a pen with hot water, sunlight, or a microwave.

You may store this medicine at room temperature for up to 30 days. Throw the medicine away if not used within 30 days. Do not put it back into the refrigerator once it has reached room temperature.

Call your doctor for instructions if you miss an appointment for your Tezspire Pre-filled Syringe.

If you are giving the medicine to yourself: Use the medicine as soon as you remember, and then return to your regular schedule. If it is already time for your next dose, skip the missed dose and take your next dose at the usual time. Do not use two doses at the same time.

Seek emergency medical help or call the Poison Help line at 1-800-222-1222.

Do not receive a "live" vaccine. The vaccine may not be as effective while you are using Tezspire Pre-filled Syringe. Live vaccines may include measles, mumps, rubella (MMR), varicella (chickenpox), live nasal flu vaccine, and others.

Other drugs may influence how Tezspire Pre-filled Syringe works, including prescription and over-the-counter medicines, vitamins, and herbal products. Inform your doctor about all the medicines you are using.

Find detailed information on biosimilars for this medication.