Ticon (Intramuscular)

Trimethobenzamide helps to treat nausea and vomiting.

You can get this medicine only with your doctor's prescription.

Trimethobenzamide will increase the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Examples of CNS depressants include antihistamines or medicines for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicines; prescription pain medicines or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of these medicines while you are using trimethobenzamide.

This medicine may cause some people to feel dizzy, lightheaded, drowsy, or less alert than usual. Make sure you know how you respond to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.

In deciding to use a medicine, you and your doctor must consider the risks of taking the medicine against the benefits it may provide. Here are important points to consider for this medicine:

Allergies

Inform your doctor if you have ever had any unusual or allergic reactions to this medicine or any other medicines. Also, let your healthcare professional know about any other allergies, such as to foods, dyes, preservatives, or animals. For over-the-counter products, carefully read the label or package ingredients.

Pediatric

There is no information available on how age affects the use of intramuscular trimethobenzamide in children. However, due to the risk of toxicity, this medicine is not safe for children. Intramuscular trimethobenzamide should never be used in children.

Geriatric

There is no information available on whether older adults are at higher risk for side effects from trimethobenzamide. However, because of this medicine's toxicity, it should be used with caution after considering less toxic alternatives that may not have worked. The recommended doses should not be exceeded, and the patient should be closely monitored during treatment.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication while breastfeeding. Weigh the potential benefits against the potential risks before using this medicine while breastfeeding.

Interactions with Medicines

Some medicines should not be taken together at all, while others can be used together with caution. In cases where an interaction might occur, your doctor may adjust the dose or take other precautions. It is particularly important for your healthcare professional to know if you are taking any of the medicines listed below while receiving this medicine. The following interactions are highlighted for their potential significance but are not exhaustive.

Using this medicine with any of the following medicines is not recommended. Your doctor may choose not to prescribe this medication to you or may adjust other medicines you are taking.

• Bromopride
• Potassium Citrate

Interactions with Food/Tobacco/Alcohol

Some medicines should not be taken around mealtimes or with certain types of food due to potential interactions. Consuming alcohol or tobacco with certain medicines may also lead to interactions. Discuss with your healthcare professional how to use your medicine with food, alcohol, or tobacco.

Other Medical Problems

Other medical conditions may impact the use of this medicine. Be sure to inform your doctor if you have any other medical issues, especially:

• Dehydration or
• Electrolyte imbalance (high or low levels of minerals in the blood) or
• High fever or
• Severe intestinal infection—These may worsen side effects.

Along with its necessary effects, a medicine may cause some unwanted effects. Not all of these side effects may happen, but if they do, you may need medical attention.

Check with your doctor right away if any of the following side effects occur:

Rare

• Body spasm, with head and heels bent backward and body bowed forward
• convulsions (seizures)
• depression
• shakiness or tremors
• skin rash
• sore throat or fever
• unusual tiredness
• vomiting (severe or continuing)
• yellow eyes or skin

Some side effects may happen that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Your health care professional may also be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue, are bothersome, or if you have any questions about them:

More common

• Drowsiness

Less common

• Blurred vision
• diarrhea
• dizziness
• headache
• muscle cramps

Other side effects not listed may also happen in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Arrestin
• Benzacot
• Stemetic
• Ticon
• Tigan
• Tribenzagan

Available Dosage Forms:

• Solution

Therapeutic Class: Antiemetic

Pharmacologic Class: Anticholinergic

Trimethobenzamide is only used to relieve or prevent nausea and vomiting. A nurse or other trained health professional will give you this medicine. This medicine is given as a shot into one of your muscles.

Your doctor may only give you a few doses of this medicine until your condition improves, and then may switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.