Tioconazole (Topical)

Tioconazole is part of a group of medicines called antifungals, which are used to treat infections caused by fungi or yeast. They work by killing the fungus or yeast or stopping its growth.

Tioconazole cream is used on the skin to treat:

• ringworm of the body (tinea corporis);
• ringworm of the foot (tinea pedis; athlete's foot);
• ringworm of the groin (tinea cruris; jock itch);
• tinea versicolor (sometimes called "sun fungus"); and
• yeast infection of the skin (cutaneous candidiasis).

Tioconazole comes in the following forms:

• Topical
• Cream (Canada)

If your skin problem does not get better within:

• 2 weeks for ringworm of the body or yeast infection of the skin, tinea versicolor, or ringworm of the groin;
• 4 to 6 weeks for ringworm of the foot;

or if it gets worse, contact your doctor.

To fully clear your infection and help prevent it from coming back, good health habits are necessary. The following steps can help reduce chafing and irritation and keep the area cool and dry:

• For patients using tioconazole for ringworm of the groin (tinea cruris; jock itch): Avoid tight-fitting underwear or underwear made from synthetic materials (like rayon or nylon). Instead, wear loose-fitting, cotton underwear.
• For patients using tioconazole for ringworm of the foot (tinea pedis; athlete's foot): Dry your feet thoroughly, especially between your toes, after bathing. Avoid socks made from wool or synthetic materials (like rayon or nylon). Instead, wear clean, cotton socks and change them daily or more often if your feet sweat a lot. Wear sandals or other well-ventilated shoes.
• For patients using tioconazole for ringworm of the body (tinea corporis): Dry yourself carefully after bathing. Avoid excessive heat and humidity if you can. Wear well-ventilated, loose-fitting clothing.

If you have any questions about these steps, consult your health care professional.

In deciding to use a medicine, you need to think about the risks of taking it compared to the benefits it may provide. This is a decision you will make with your doctor. For this medicine, consider the following:

Allergies

Inform your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also, let your healthcare professional know if you have other allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, carefully read the label or package ingredients.

Pediatric

There is no specific information comparing the use of this medicine in children to its use in other age groups, but it is not expected to cause different side effects or problems in children compared to adults.

Geriatric

Many medicines have not been studied specifically in older adults. Therefore, it may not be known if they work exactly the same way in older people as they do in younger adults. There is no specific information comparing the use of tioconazole in older adults to its use in other age groups, but it is not expected to cause different side effects or problems in older people compared to younger adults.

Interactions with Medicines

Some medicines should not be used together at all, while in other cases, two different medicines may be used together even if there might be an interaction. In these situations, your doctor may want to adjust the dose or take other precautions. Inform your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be taken at or around the time of eating food or certain types of food due to possible interactions. Using alcohol or tobacco with some medicines may also lead to interactions. Discuss with your healthcare professional about using your medicine with food, alcohol, or tobacco.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may happen, if they do occur, they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common

• Burning
• itching
• redness
• skin rash
• swelling
• or other signs of skin irritation not present before use of this medicine

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In Canada

• Gyne Cure
• Trosyd Af
• Trosyd J

Chemical Class: Imidazole

Apply enough tioconazole to cover the affected and surrounding skin areas, and rub in gently.

Keep this medicine away from the eyes.

Do not apply an occlusive dressing (airtight covering, such as kitchen plastic wrap) over this medicine unless you have been directed to do so by your doctor. To do so may cause irritation of the skin.

To help clear up your infection completely, it is very important that you keep using tioconazole for the full time of treatment, even if your symptoms begin to clear up after a few days. Since fungus infections may be very slow to clear up, you may have to continue using this medicine every day for several weeks or more. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For topical cream dosage form: For ringworm of the body or yeast infection of the skin: Adults—Use two times a day for 2 to 4 weeks. Children— Dose must be determined by your doctor. For ringworm of the foot: Adults—Use two times a day for up to 6 weeks. Children— Dose must be determined by your doctor. For ringworm of the groin: Adults—Use two times a day for up to 2 weeks. Children— Dose must be determined by your doctor. For tinea versicolor (“sun fungus”): Adults—Use two times a day for 1 to 4 weeks. Children— Dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.