Tivicay PD

Tivicay PD is an antiviral medicine that is used with other medications to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). This medicine is not a cure for HIV or AIDS.

Tivicay PD is for use in adults and infants weighing at least 4.4 pounds (2 kilograms).

Tivicay PD may also be used for purposes not listed in this medication guide.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

You may take Tivicay PD with or without food.

Do not crush or chew a dispersible tablet whole. Swallow the tablet whole, or place it in a small amount of water. Allow the tablet to disperse (it will not dissolve completely). Stir and give the mixture to the child right away. The amount of water needed will depend on the number of tablets needed for your child's dose. Follow the instructions provided with your medicine.

The Tivicay PD regular tablet and dispersible tablet cannot be used in the same dosages. Take only the pill form your doctor has prescribed. Avoid medication errors by always checking the medicine you receive at the pharmacy.

Tivicay PD doses are based on weight in children. Your child's dose needs may change if the child gains or loses weight.

While using Tivicay PD, you may need frequent blood tests.

If you've ever had hepatitis B, using Tivicay PD can cause this virus to become active or get worse. You may need frequent liver function tests while using Tivicay PD and for several months after you stop.

Use all HIV medications as directed and read all medication guides you receive. Do not change your dose or dosing schedule without your doctor's advice. Every person with HIV should remain under the care of a doctor.

Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with any packet or canister of moisture-absorbing preservative.

You should not use Tivicay PD if you are also taking dofetilide (Tikosyn).

Taking Tivicay PD during the first trimester of pregnancy may cause birth defects. Use effective birth control to prevent pregnancy while you are using this medicine.

You should not use Tivicay PD if you are allergic to it, or if you are also taking dofetilide (Tikosyn).

Tell your doctor if you have ever had:

• liver disease, especially hepatitis B or C.

You may need to have a negative pregnancy test before starting this treatment.

Tivicay PD may harm an unborn baby if you take the medicine at the time of conception or during the first 12 weeks of pregnancy. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.

HIV can be passed to your baby if the virus is not controlled during pregnancy. If you are pregnant, your name may be listed on a registry to track any effects of antiviral medicine on the baby. Use your medications properly to control HIV.

Women with HIV or AIDS should not breastfeed. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

Stop taking Tivicay PD and get emergency medical help if you notice signs of an allergic reaction: fever, feeling generally unwell, difficulty breathing, fatigue; joint or muscle pain, blisters or sores in your mouth, redness or swelling in your eyes; skin that is blistering or peeling; swelling of your face, lips, tongue, or throat.

Tivicay PD may cause serious side effects. Call your doctor immediately if you experience:

• the first sign of any skin rash, no matter how mild; or
• liver problems—nausea, vomiting, loss of appetite, pain in the upper stomach, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Tivicay PD can affect your immune system, which may lead to certain side effects (even weeks or months after you have taken this medicine). Inform your doctor if you have:

• signs of a new infection—fever, night sweats, swollen glands, cold sores, cough, wheezing, diarrhea, weight loss;
• difficulty speaking or swallowing, balance problems or issues with eye movement, weakness or tingling sensations; or
• swelling in your neck or throat (enlarged thyroid), changes in your menstrual cycle, impotence.

Common side effects of Tivicay PD may include:

• headache;
• fatigue; or
• sleep problems (insomnia).

This is not a complete list of side effects, and others may occur. Contact your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

Take the medicine as soon as possible, but skip the missed dose if it is almost time for your next dose. Do not take two doses at the same time.

Get your prescription refilled before you completely run out of medicine.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Using Tivicay PD will not prevent your disease from spreading. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

Some medicines can make Tivicay PD much less effective when taken at the same time. If you take any of the following medicines, take your medicine dose 2 hours before or 6 hours after you take the other medicine.

• antacids or laxatives that contain calcium, magnesium, or aluminum (such as Amphojel, Di-Gel Maalox, Milk of Magnesia, Mylanta, Pepcid Complete, Rolaids, Rulox, Tums, and others), or the ulcer medicine sucralfate (Carafate);
• buffered medicine; or
• vitamin or mineral supplements that contain calcium or iron (but if you take Tivicay PD with food, you can take these supplements at the same time).

Many drugs can affect Tivicay PD. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.