Trimethobenzamide (oral/injection)

Trimethobenzamide is used to treat nausea and vomiting that are related to surgery or caused by stomach flu.

Trimethobenzamide may also be used for reasons not mentioned in this medication guide.

Follow all instructions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Trimethobenzamide is usually taken 3 or 4 times per day. Follow your doctor's dosing instructions very carefully.

Trimethobenzamide oral is taken by mouth. Trimethobenzamide injection is injected into a muscle by a healthcare provider.

Store at room temperature away from moisture and heat.

Follow all the instructions on your medicine label and package. Inform all your healthcare providers about any medical conditions, allergies, and all medications you are taking.

You should not use trimethobenzamide if you are allergic to it.

Tell your doctor if you have ever had:

• liver disease; or
• kidney disease.

Do not give this medication to a child or teenager without medical advice, especially if the child has a fever, flu symptoms, or chicken pox.

It is not known whether trimethobenzamide will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breast-feed while using trimethobenzamide. Ask your doctor about any risk.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking trimethobenzamide and call your doctor right away if you have:

• twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;
• trouble speaking or swallowing;
• problems with thinking or memory;
• pain, stiffness, or unusual muscle spasms in your neck;
• tremors, feeling restless, or being unable to sit still;
• jaundice (yellowing of the skin or eyes);
• a seizure (convulsions); or
• low blood cell counts—fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed, or short of breath.

Serious side effects may be more likely in older adults.

Common side effects of trimethobenzamide may include:

• headache, muscle cramps;
• dizziness, drowsiness;
• confusion, depressed mood;
• blurred vision;
• diarrhea; or
• pain, stinging, burning, redness, or swelling where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Usual Adult Dose for Nausea/Vomiting:

Oral: 300 mg orally 3 or 4 times a dayIM Injection: 200 mg IM 3 or 4 times a dayComment: Dosage should be adjusted according to the therapy indication, symptom severity, and patient response.Uses:-Treatment of postoperative nausea and vomiting-Treatment of nausea associated with gastroenteritis

Since trimethobenzamide is taken as needed, you may not have a regular dosing schedule. If you miss a dose and it's almost time for your next dose, just skip the missed dose. Do not take two doses at the same time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

• Avoid driving or hazardous activity until you know how trimethobenzamide will affect you. Your reactions could be impaired.

• Drinking alcohol with this medicine can cause side effects.

• Do not share this medicine with another person, even if they have the same symptoms you have.

Using trimethobenzamide with other medications that cause drowsiness can increase this effect. Check with your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Other medications may impact how trimethobenzamide works, including prescription and over-the-counter medicines, vitamins, and herbal products. Inform your doctor about all the medicines you are currently taking and any new medicine you begin or stop using.