Trumenba (Intramuscular)

Meningococcal vaccine is a type of medicine that helps your body prevent infections caused by certain groups (A, B, C, W, and Y) of meningococcal bacteria (Neisseria meningitides). The vaccine helps your body create its own defense (antibodies) against the disease.

Meningococcal infection can lead to serious illnesses, such as meningococcal meningitis, which affects the brain, and meningococcemia, which affects the blood. These illnesses are more likely to happen in young children and in people with certain diseases or conditions that make them more vulnerable to meningococcal infection or more likely to face serious issues from it.

Getting vaccinated against meningococcal disease is advised for people who are at risk of getting the disease because:

• They have certain diseases or conditions that make them more vulnerable to a meningococcal infection or more likely to face serious issues from it.
• They are living in, working in, or visiting areas where there is a high chance of getting meningococcal disease.

This vaccine is recommended for individuals aged 10 to 25 years.

This vaccine should only be given by or under the supervision of your doctor.

Be sure to tell your doctor about any side effects you have after getting this vaccine.

This vaccine can cause serious allergic reactions, including anaphylaxis, which can be life-threatening and needs immediate medical help. Contact your doctor right away if you have a rash, itching, a fast heartbeat, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after getting the vaccine.

Fainting can happen after you get this vaccine. Your doctor may want to monitor you after the injection to prevent and manage fainting.

This vaccine may not protect everyone who receives it. It will not treat symptoms of meningococcal infection if you already have the disease.

In deciding to get a vaccine, you and your doctor need to think about the risks of the vaccine compared to its benefits. Consider the following for this vaccine:

Allergies

Let your doctor know if you have ever had any unusual or allergic reactions to this medicine or any other medicines. Also, inform your healthcare professional about any other allergies you may have, like allergies to foods, dyes, preservatives, or animals. For non-prescription products, carefully read the label or package ingredients.

Pediatric

There have not been enough studies on how the Penbraya™ vaccine affects children younger than 10 years old. It is not known if it is safe or effective for them.

Geriatric

There have not been enough studies on how the Penbraya™ vaccine affects older adults. It is not known if it is safe or effective for geriatric patients.

Breast Feeding

Research suggests that this medication poses minimal risk to infants when used during breastfeeding. However, there are no adequate studies in women to determine the risk to infants when using this medication while breastfeeding. Consider the potential benefits and risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should not be used together, while others may be used together even if an interaction could happen. In such cases, your doctor may adjust the dose or take other precautions. It is very important that your healthcare professional knows if you are taking any of the following medicines when you receive this vaccine. The following interactions are selected based on their potential significance and may not include all possibilities.

Using this vaccine with any of the following medicines is usually not recommended but may be necessary in some situations. If both medicines are prescribed together, your doctor may adjust the dose or frequency for one or both medicines.

• Elivaldogene Autotemcel
• Measles Virus Vaccine, Live
• Teplizumab-mzwv
• Ublituximab-xiiy

Interactions with Food/Tobacco/Alcohol

Some medicines should not be taken around mealtimes or with certain foods due to possible interactions. Using alcohol or tobacco with certain medicines may also lead to interactions. Discuss with your healthcare professional how to use your medicine with food, alcohol, or tobacco.

Other Medical Problems

Having other medical issues may affect your use of this vaccine. Make sure to inform your doctor about any other medical conditions, especially:

• Immune system problems—This may reduce the effectiveness of the vaccine.

• Nerve problem (e.g., Guillain-Barré syndrome), history of—Use with caution. This condition may worsen.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may happen, if they do happen, they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

• Chest tightness
• cough
• difficulty swallowing
• dizziness
• fainting
• fast heartbeat
• hives, itching, skin rash
• inability to move arms and legs
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• sudden numbness and weakness in the arms and legs
• trouble breathing
• unusual tiredness or weakness

Some side effects may happen that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
• chills
• diarrhea
• fever
• headache
• joint pain
• muscle pain
• vomiting

Other side effects not listed may also happen in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Bexsero
• Menactra
• MenQuadfi
• Menveo
• Trumenba

Available Dosage Forms:

• Suspension
• Kit
• Solution

Therapeutic Class: Vaccine

A nurse or other trained health professional will give you this medicine in a medical facility. It is given as a shot into one of your muscles.

This vaccine is given in 2 doses at least 6 months apart.