Twilite

Twilite is an antihistamine that helps with sneezing, a runny nose, watery eyes, hives, skin rashes, itching, and other cold or allergy symptoms.

Twilite is also used to prevent motion sickness, help with sleep, and treat certain symptoms of Parkinson's disease. This sleep aid is not for children younger than 12 years old.

There are many brands and forms of diphenhydramine available. Not all brands are included in this leaflet.

Twilite may also be used for purposes not mentioned in this medication guide.

Use exactly as directed on the label or as prescribed by your doctor. Twilite is meant for short-term use until your symptoms go away.

Taking too much Twilite can cause serious heart problems, seizures, coma, or death.

Always follow the instructions on the medicine label when giving Twilite to a child. Do not use this medicine just to make a child sleepy. Misusing antihistamines in very young children can lead to death.

For motion sickness, take Twilite 30 minutes before you will be in a situation that causes you motion sickness (like a long car ride, airplane or boat travel, amusement park rides, etc.). Continue taking this medicine with meals and at bedtime for the duration of the motion-sickness situation.

As a sleep aid, take Twilite within 30 minutes before bedtime.

You must chew the chewable tablet before swallowing it.

Measure liquid medicine carefully. Use the dosing syringe provided or a medicine dose-measuring device (not a kitchen spoon).

Remove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet in your mouth and let it dissolve without chewing. Swallow several times as the tablet dissolves.

Call your doctor if the condition you are treating with Twilite does not improve, or if you have a fever with a headache, cough, or skin rash.

Do not use Twilite for more than 2 weeks to treat sleep problems, or for more than 7 days to treat cold or allergy symptoms.

Twilite can interfere with the results of allergy skin tests. Inform any doctor treating you that you are using Twilite.

Store at room temperature away from moisture and heat.

Use Twilite exactly as directed. Taking too much Twilite can cause serious heart problems, seizures, coma, or death.

Do not use this medicine to make a child sleepy. Twilite sleep aid medicine is not for use in children younger than 12 years old.

You should not use Twilite if you are allergic to it.

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

• an enlarged prostate or problems with urination;
• asthma, chronic obstructive pulmonary disease (COPD), or any other breathing issue;
• glaucoma; or
• a thyroid problem.

Ask a doctor before using this medicine if you are pregnant or breastfeeding. Twilite may slow down breast milk production.

Get emergency medical help if you have signs of an allergic reaction: hives; trouble breathing; swelling of your face, lips, tongue, or throat.

Twilite may cause serious side effects. Stop using Twilite and call your doctor right away if you have:

• severe drowsiness; or
• painful or difficult urination.

Side effects like dry mouth, constipation, and confusion may happen more often in older adults.

Common side effects of Twilite may include:

• drowsiness;
• dry eyes, blurred vision;
• dry mouth, nose, or throat;
• decreased urination;
• constipation;
• feeling restless or excited (especially in children); or
• daytime drowsiness or "hangover" feeling after using it at night.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You can report side effects to FDA at 1-800-FDA-1088.

Since Twilite is taken as needed, you might not have a regular dosing schedule. If you miss a dose and it’s almost time for your next dose, just skip the missed dose. Do not take two doses at the same time.

Seek emergency medical help or call the Poison Help line at 1-800-222-1222. Taking too much diphenhydramine can be deadly.

Signs of an overdose may include vomiting, confusion, extreme drowsiness, ringing in your ears, not being able to urinate, very dry eyes and mouth, dilated pupils, rapid heartbeats, shaking, agitation, hallucinations, or seizures.

Do not drive or do anything dangerous until you know how Twilite will affect you. Your reactions might be slowed down.

Drinking alcohol can make some side effects of diphenhydramine worse.

Check with a doctor or pharmacist before using any other medicine that may have Twilite in it. This includes medications for sleep, cold/allergy symptoms, or anti-itch creams for the skin. Taking too much of this medicine can lead to a fatal overdose.

Ask a doctor or pharmacist before using Twilite with any other medicines, especially those that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Inform your doctor about all your current medicines and any medicine you begin or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.