Tylenol Extra Strength PM

Acetaminophen is a pain reliever and a fever reducer. Diphenhydramine is an antihistamine.

Tylenol Extra Strength PM is a combination medicine used to treat occasional sleeplessness that comes with minor aches and pains. Tylenol Extra Strength PM is not for treating sleeplessness without pain, or sleep problems that happen frequently.

Tylenol Extra Strength PM is also used to relieve minor aches and pains such as headache, back pain, joint or muscle pain, tooth pain, or menstrual cramps.

Tylenol Extra Strength PM is also used to help with runny nose, sneezing, itchy nose and throat, and pain or fever caused by allergies, the common cold, or the flu.

Tylenol Extra Strength PM may also be used for other purposes not listed in this medication guide.

Use exactly as directed on the label, or as prescribed by your doctor. Tylenol Extra Strength PM is only for short-term use until your symptoms go away.

Do not take more of Tylenol Extra Strength PM than is recommended. An overdose of acetaminophen can harm your liver or cause death. Taking too much diphenhydramine can lead to serious heart issues, seizures, coma, or death.

Tylenol Extra Strength PM is not for use in anyone younger than 12 years old. Do not use this medicine to make a child sleepy. Death can happen from the misuse of antihistamines in very young children.

Do not use this medicine for longer than 2 weeks to treat sleep problems, or longer than 7 days to treat cold or allergy symptoms.

Call your doctor if you still have a fever after 3 days, or if you still have pain after 10 days (or 5 days if you are 12-17 years old). Also, call your doctor if your symptoms get worse, or if you notice any redness or swelling.

If you need surgery or medical tests, tell the doctor in advance if you have taken this medicine within the past few days.

Store at room temperature away from moisture and heat.

Use Tylenol Extra Strength PM exactly as directed. Taking too much acetaminophen can harm your liver or cause death. Taking too much diphenhydramine can result in serious heart issues, seizures, coma, or death.

Do not use this medicine to make a child sleepy. This medicine is not for anyone younger than 12 years old.

Ask a doctor or pharmacist before using any other medicine that may contain acetaminophen or diphenhydramine. Taking too much of either can lead to a fatal overdose.

Drinking alcohol may increase your chance of liver damage while using acetaminophen.

Stop using this medicine and call your doctor immediately if you notice skin redness or a rash that spreads and causes blistering and peeling.

Ask a doctor before taking medicine that contains acetaminophen if you have ever had liver disease, or if you drink more than 3 alcoholic beverages per day.

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

• liver disease;
• an enlarged prostate or problems urinating;
• asthma, chronic obstructive pulmonary disease (COPD), emphysema, or another breathing problem;
• glaucoma; or
• a condition for which you take warfarin (Coumadin, Jantoven).

Ask a doctor before using this medicine if you are pregnant or breastfeeding. Diphenhydramine may slow breast milk production.

Get emergency medical help if you notice signs of an allergic reaction: hives; trouble breathing; swelling of your face, lips, tongue, or throat.

In rare cases, acetaminophen may cause a serious skin reaction that could be life-threatening. This can happen even if you have taken acetaminophen before and had no issues. Stop taking this medicine and call your doctor immediately if you notice skin redness or a rash that spreads and causes blistering and peeling. If you experience this type of reaction, you should never take any medicine that contains acetaminophen again.

This medicine may cause serious side effects. Stop using the medicine and call your doctor right away if you have:

• severe drowsiness;
• painful or difficult urination; or
• liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects of Tylenol Extra Strength PM may include:

• drowsiness;
• constipation;
• decreased urination;
• dry eyes, blurred vision; or
• dry mouth, nose, or throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Since Tylenol Extra Strength PM is taken as needed, you might not have a set dosing schedule. If you miss a dose and it’s almost time for your next dose, just skip the missed dose. Do not take two doses at the same time.

Seek emergency medical help or call the Poison Help line at 1-800-222-1222. Taking too much can be deadly or harm your liver.

Signs of an overdose may include not feeling hungry, throwing up, feeling weak, confusion, ringing in your ears, pain in the upper stomach, dark urine, not being able to urinate, very dry eyes and mouth, yellowing of your skin or eyes, big pupils, fast heart rate, shaking, agitation, hallucinations, or seizures.

Do not drive or do anything dangerous until you know how Tylenol Extra Strength PM will affect you. Your reactions might be slower.

Talk to a doctor or pharmacist before using any other medicine that might have acetaminophen or diphenhydramine. This includes medicines for pain, fever, swelling, cold/flu symptoms, or anti-itch creams. Taking too much acetaminophen or diphenhydramine can cause a fatal overdose.

Drinking alcohol might increase your chance of liver damage while taking acetaminophen.

Ask a doctor or pharmacist before using Tylenol Extra Strength PM with any other medicines, especially those that can cause drowsiness (like opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Inform your doctor about all your current medicines and any medicine you begin or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.