Unisom PM Pain

Acetaminophen is a pain reliever and fever reducer. Diphenhydramine is an antihistamine.

Unisom PM Pain is a combination medicine used to treat occasional insomnia related to minor aches and pains. Unisom PM Pain is not for treating sleeplessness when there is no pain, or for sleep problems that happen frequently.

Unisom PM Pain is also used to relieve minor aches and pains such as headache, back pain, joint or muscle pain, tooth pain, or menstrual cramps.

Unisom PM Pain is also used to treat runny nose, sneezing, itchy nose and throat, and pain or fever caused by allergies, the common cold, or the flu.

Unisom PM Pain may also be used for purposes not listed in this medication guide.

Use exactly as directed on the label, or as prescribed by your doctor. Unisom PM Pain is only for short-term use until your symptoms improve.

Do not take more of Unisom PM Pain than is recommended. An overdose of acetaminophen can harm your liver or cause death. Taking too much diphenhydramine can result in serious heart problems, seizures, coma, or death.

Unisom PM Pain is not for use in anyone younger than 12 years old. Do not use the medicine to make a child sleepy. Misusing antihistamines in very young children can lead to death.

Do not use this medicine for longer than 2 weeks to treat sleep problems, or longer than 7 days to treat cold or allergy symptoms.

Call your doctor if you still have a fever after 3 days, or if you still have pain after 10 days (or 5 days if you are 12-17 years old). Also call your doctor if your symptoms worsen, or if you notice any redness or swelling.

If you need surgery or medical tests, inform the doctor beforehand if you have taken this medicine within the past few days.

Store at room temperature away from moisture and heat.

Use Unisom PM Pain exactly as directed. Taking too much acetaminophen can harm your liver or lead to death. Taking too much diphenhydramine can cause serious heart issues, seizures, coma, or death.

Do not use this medicine to make a child sleepy. This medicine is not for anyone younger than 12 years old.

Ask a doctor or pharmacist before using any other medicine that may contain acetaminophen or diphenhydramine. Taking too much of either can result in a fatal overdose.

Drinking alcohol may raise your risk of liver damage while you are taking acetaminophen.

Stop taking this medicine and contact your doctor immediately if you experience skin redness or a rash that spreads and causes blistering and peeling.

Ask a doctor before taking medicine that contains acetaminophen if you have ever had liver disease, or if you drink more than 3 alcoholic beverages per day.

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

• liver disease;
• an enlarged prostate or urination problems;
• asthma, chronic obstructive pulmonary disease (COPD), emphysema, or other breathing disorder;
• glaucoma; or
• a condition for which you take warfarin (Coumadin, Jantoven).

Ask a doctor before using this medicine if you are pregnant or breastfeeding. Diphenhydramine may slow breast milk production.

Get emergency medical help if you notice signs of an allergic reaction: hives; trouble breathing; swelling of your face, lips, tongue, or throat.

In rare cases, acetaminophen may lead to a severe skin reaction that can be deadly. This can happen even if you have taken acetaminophen before without any issues. Stop taking this medicine and contact your doctor immediately if you experience skin redness or a rash that spreads and results in blistering and peeling. If you have this kind of reaction, you should never take any medicine that contains acetaminophen again.

This medicine may cause serious side effects. Stop using it and call your doctor right away if you experience:

• severe drowsiness;
• painful or difficult urination; or
• liver problems—loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects of Unisom PM Pain may include:

• drowsiness;
• constipation;
• decreased urination;
• dry eyes, blurred vision; or
• dry mouth, nose, or throat.

This is not a complete list of side effects, and others may happen. Contact your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

Since Unisom PM Pain is taken as needed, you might not have a regular dosing schedule. If you miss a dose and it's almost time for your next dose, just skip the missed dose. Do not take two doses at the same time.

Seek emergency medical help or call the Poison Help line at 1-800-222-1222. Taking too much can be fatal or harm your liver.

Signs of an overdose may include loss of appetite, vomiting, weakness, confusion, ringing in your ears, upper stomach pain, dark urine, little to no urination, very dry eyes and mouth, yellowing of your skin or eyes, dilated pupils, fast heartbeats, tremor, agitation, hallucinations, or seizure.

Do not drive or engage in dangerous activities until you know how Unisom PM Pain will affect you. Your reactions may be affected.

Talk to a doctor or pharmacist before using any other medicine that may have acetaminophen or diphenhydramine. This includes medicines for pain, fever, swelling, cold/flu symptoms, or anti-itch medicine for the skin. Taking too much acetaminophen or diphenhydramine can lead to a fatal overdose.

Drinking alcohol may raise your risk of liver damage while taking acetaminophen.

Ask a doctor or pharmacist before using Unisom PM Pain with any other medicines, especially those that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Inform your doctor about all your current medicines and any medicine you begin or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.