Veligrotug

Veligrotug is used in adults to treat thyroid eye disease, no matter the stage of the disease or how long you have been affected.

Veligrotug may also be used for reasons not mentioned in this medication guide.

Veligrotug is given through an infusion into a vein. A healthcare provider will administer this infusion.

Veligrotug is typically given once every 3 weeks for a total of 5 doses.

This medicine must be infused slowly, and the process can take 30 to 45 minutes to finish.

Doses are determined by your weight. Your dose may change if you gain or lose weight.

Your blood sugar and hearing may need to be checked before, during, and after treatment.

You may be prescribed other medications to help manage specific side effects. Continue taking these medicines for as long as your doctor has instructed.

Use only as directed. Inform your doctor if you are taking other medicines or have any other medical conditions or allergies.

Tell your doctor if you have or have ever had:

• hearing problems;
• inflammatory bowel disease; or
• diabetes or hyperglycemia (high blood sugar).

Veligrotug may harm an unborn baby. You may need to have a pregnancy test before starting this treatment. Use effective birth control before, during, and for at least 6 months after your last dose. Tell your doctor if you become pregnant.

Ask a doctor if it is safe to breastfeed while using veligrotug.

Get emergency medical help if you have signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.

Some side effects may occur during the infusion. Tell your medical caregiver if you feel dizzy, nauseous, light-headed, itchy, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.

Veligrotug may cause serious side effects. Call your doctor right away if you have:

• severe hearing problems;
• high blood sugar—this includes increased thirst, increased urination, dry mouth, fruity breath odor; or
• inflammatory bowel disease—this includes diarrhea (with or without blood), rectal bleeding with stomach pain or cramps, a feeling of not completely emptying your bowels, sudden bowel movements, or loss of bowel control.

Common side effects of veligrotug may include:

• muscle spasm;
• nausea, diarrhea;
• headache, tiredness;
• high blood sugar;
• hearing problems;
• nasal congestion, sore throat, and runny nose;
• high blood pressure;
• dry skin; or
• abnormal blood tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Call your doctor for guidance if you miss an appointment for your Veligrotug infusion.

In a medical setting, an overdose would be treated quickly.

Follow your doctor's instructions regarding any limits on food, drinks, or activities.

Other drugs may affect veligrotug, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you are using.