VESIcare LS

VESIcare LS helps treat symptoms of overactive bladder, like needing to urinate often or urgently, and incontinence (leaking urine).

The oral suspension (liquid) form of VESIcare LS is used to treat overactive bladder caused by a neurological disorder (such as multiple sclerosis or spinal cord injury) in children who are at least 2 years old when other medicines cannot be used or have not been effective.

VESIcare LS may also be used for reasons not mentioned in this medication guide.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

VESIcare LS is usually taken once per day with or without food. Follow your doctor's instructions.

Do not crush, chew, or break the tablet. Swallow it whole.

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Take the tablet with water.

After taking VESIcare LS liquid, drink a glass of water or milk. Avoid taking the liquid with food or other drinks or you may have a bitter aftertaste.

Store VESIcare LS in the original container at room temperature, away from moisture and heat. Keep the bottle tightly closed when not in use. Throw away any unused liquid 28 days after you first opened the bottle.

You should not use VESIcare LS if you have untreated or uncontrolled narrow-angle glaucoma, a blockage in your digestive tract (stomach or intestines), or if you are unable to urinate.

You should not use VESIcare LS if you are allergic to it, or if you have:

• untreated or uncontrolled narrow-angle glaucoma;
• a stomach disorder that causes delayed emptying; or
• if you are unable to urinate.

Tell your doctor if you have ever had:

• glaucoma;
• liver disease;
• kidney disease;
• trouble emptying your bladder (or you have a weak stream of urine);
• slow digestion;
• a blockage in your stomach or intestines; or
• long QT syndrome.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breastfeed while using VESIcare LS.

Get emergency medical help if you have signs of an allergic reaction (hives, difficulty breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

VESIcare LS may cause serious side effects. Stop using VESIcare LS and call your doctor right away if you experience:

• severe stomach pain, or constipation lasting 3 days or longer;
• pain or burning during urination;
• headache, confusion, drowsiness, hallucinations;
• vision changes, eye pain, or seeing halos around lights;
• little or no urination, pain or burning during urination;
• signs of dehydration--dizziness, tiredness, feeling very thirsty or hot, decreased sweating, or hot and dry skin; or
• high potassium level--nausea, weakness, tingling sensation, chest pain, irregular heartbeats, loss of movement.

Common side effects of VESIcare LS may include:

• blurred vision;
• dry mouth, dry eyes;
• painful urination;
• constipation; or
• heat stroke--decreased sweating, dry skin, dizziness, tiredness, nausea, feeling hot.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Tablets: If you miss a dose, take your next dose at the usual time. Do not take 2 doses on the same day.

Oral suspension: Take the medicine as soon as possible, but if you are more than 12 hours late for the dose, skip the missed dose. Do not take two doses at the same time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Avoid driving or hazardous activity until you know how VESIcare LS will affect you. Your reactions could be impaired.

Avoid becoming overheated or dehydrated during exercise and in hot weather. VESIcare LS can decrease perspiration and you may be more prone to heat stroke.

Sometimes, it is not safe to use certain medications together. Some drugs can change the levels of other drugs in your blood, which may increase side effects or make the medications less effective.

Many drugs can affect VESIcare LS. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.