Vivelle-Dot (skin patch)

Estradiol is a form of estrogen, a women sex hormone produced by the ovaries. Estrogen is needed for lots of processes in the body.

Vivelle-Dotes are utilized to deal with particular signs and symptoms of menopause such as warm flashes, and vaginal dryness, burning, and irritation. Vivelle-Dot is likewise used to prevent postmenopausal osteoporosis, or to treat ovarian problems.

Vivelle-Dot might likewise be made use of for purposes not provided in this drug guide.

You need to not utilize estradiol if you have: undiagnosed genital bleeding, liver condition, coronary artery illness, if you will have major surgery, or if you have ever had a cardiovascular disease, a stroke, a blood clot, or cancer cells of the bust, uterus/cervix, or vagina.

Do not make use of if you are expecting.

Estradiol might enhance your danger of developing a condition that might lead to uterine cancer cells. Report any type of unusual vaginal blood loss right now.

Utilizing Vivelle-Dot can increase your danger of embolism, stroke, heart attack, or cancer cells of the breast, uterus, or ovaries. Estradiol must not be utilized to prevent cardiovascular disease, stroke, or dementia.

You ought to not use estradiol if you are allergic to it, or if you have:

• unusual vaginal bleeding that has actually not been checked by a doctor;
• liver illness;
• coronary artery disease;
• a bleeding condition;
• a history of cardiac arrest, stroke, or blood clot; or
• a background of hormone-related cancer cells, or cancer of the bust, uterus/cervix, or vaginal area.

Do not utilize estradiol if you are expectant. Inform your doctor right now if you conceive during treatment.

Making use of estradiol can boost your danger of blood clots, stroke, or cardiac arrest. You are even more in danger if you have high blood pressure, diabetes mellitus, high cholesterol, if you are overweight, or if you smoke.

Estradiol ought to not be used to stop heart disease, stroke, or mental deterioration, due to the fact that this medication may really raise your risk of developing these problems.

Inform your doctor if you have ever before had:

• heart disease;
• liver troubles, or jaundice brought on by maternity or taking hormonal agents;
• a thyroid disorder;
• gallbladder illness;
• kidney illness;
• asthma;
• epilepsy or other seizure problem;
• migraine frustrations;
• lupus;
• porphyria (a genetic enzyme problem that causes signs impacting the skin or nervous system);.
• endometriosis or uterine fibroid tumors;.
• high levels of calcium in your blood; or.
• hereditary angioedema (an immune system problem).

Making use of estradiol may increase your danger of cancer of the breast, uterus, or ovaries. Talk with your medical professional regarding this risk.

Estradiol can reduce bust milk manufacturing. Inform your doctor if you are breast-feeding.

Obtain emergency medical aid if you have signs of an allergy: hives; hard breathing; swelling of your face, lips, tongue, or throat.

Get rid of the skin patch and call your physician at the same time if you have:

• heart attack signs-- chest discomfort or stress, discomfort infecting your jaw or shoulder, queasiness, sweating;
• enhanced blood pressure-- severe migraine, obscured vision, battering in your neck or ears, stress and anxiety, nosebleed;
• signs of a stroke-- sudden numbness or weak point (particularly on one side of the body), abrupt serious frustration, slurred speech, problems with vision or equilibrium;
• indicators of an embolism-- sudden vision loss, stabbing upper body pain, feeling short of breath, divulging blood, discomfort or heat in one or both legs;
• swelling or inflammation in your stomach;
• jaundice (yellowing of the skin or eyes);.
• unusual vaginal bleeding, pelvic pain;.
• a bust lump;.
• memory issues, complication, unusual habits; or.
• high degrees of calcium in your blood-- queasiness, vomiting, constipation, raised thirst or urination, muscular tissue weak point, bone discomfort, lack of energy.

Common side effects of Vivelle-Dot may include:.

• migraine, pain in the back;.
• stuffy nose, sinus pain, sore throat;.
• vaginal itchiness or discharge, changes in your menstrual periods, innovation bleeding;.
• bloating, tummy cramps, nausea, throwing up;.
• breast discomfort;.
• inflammation or inflammation where the spot was worn;.
• thinning scalp hair; or.
• fluid retention (swelling, quick weight gain).

This is not a complete checklist of negative effects and others might occur. Call your doctor for clinical recommendations regarding side effects. You might report side effects to FDA at 1-800-FDA-1088.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Apply the skin patch to clean, dry skin on your stomach or buttocks. Press the patch firmly into place for at least 10 seconds. Choose a different spot within these skin areas each time you apply a new patch. Do not use the same skin area twice within 7 days. Avoid skin that is irritated or damaged.

Do not apply a skin patch to your breasts. Do not apply a patch where it might be rubbed off by tight clothing, such as under an elastic waistband. Never cut a skin patch.

If a patch falls off, try sticking it back into place. If it does not stick well, put on a new patch on a different skin area and leave it on only for the rest of your wearing time. Do not change your patch removal schedule.

Remove the patch and apply a new one on the same day(s) each week to stay on your once-weekly or twice-weekly schedule.

Estradiol may increase your risk of developing a condition that may lead to uterine cancer. Your doctor may prescribe a progestin to help lower this risk. Report any unusual vaginal bleeding right away.

If you need major surgery or will be on long-term bed rest, you may need to stop using Vivelle-Dot for a short time. Any doctor or surgeon who treats you should know that you are using estradiol.

Your doctor should check your progress on a regular basis to determine whether you should continue this treatment. Self-examine your breasts for lumps on a monthly basis, and have regular mammograms while using Vivelle-Dot.

Store patches at room temperature away from moisture and heat. Keep each patch in its pouch until you are ready to use it.

After removing a skin patch, fold it in half so it sticks together. Discard the folded patch in a place children and pets cannot get to.

If you neglect to alter your patch, transform it as soon as you keep in mind or wait until your following set up patch modification. Do not apply two patches at once.

Seek emergency situation clinical interest or call the Toxin Customer service at 1-800-222-1222.

Avoid cigarette smoking. It can considerably increase your threat of embolism, stroke, or cardiac arrest while making use of estradiol.

Grapefruit may interact with estradiol and bring about undesirable side effects. Avoid making use of grapefruit products.

Avoid utilizing lotions, creams, or powders on the skin where you use the spot, or it may not adhere to your skin.

In some cases it is not risk-free to make use of particular medicines at the very same time. Some medicines can influence your blood levels of other medications you take, which might enhance side effects or make the medicines less reliable.

Other drugs may influence estradiol, consisting of prescription and over the counter medicines, vitamins, and organic items. Inform your physician concerning all your existing medicines and any type of medication you begin or quit making use of.