Voltaren-XR (Oral)

Diclofenac is a nonsteroidal anti-inflammatory medicine (NSAID) used to deal with mild-to-moderate discomfort, and aids to ease signs and symptoms of arthritis (eg, osteoarthritis or rheumatoid joint inflammation), such as inflammation, swelling, stiffness, and joint pain. This medication does not heal arthritis and will only assist you as long as you remain to take it.

This medicine is additionally used to deal with ankylosing spondylitis, which is a sort of joint inflammation that impacts the joints in the spine, and various other painful conditions such as menstruation cramps.

Diclofenac is likewise used to treat severe migraine attacks, with or without mood, in grownups. It will certainly not protect against or lessen the number of migraine headache assaults.

This medicine is readily available only with your physician's prescription.

It is very vital that your doctor examine your progression at regular gos to. This will certainly enable your physician to see if the medication is working correctly and to make a decision if you ought to remain to take it. Blood and urine examinations may be needed to check for undesirable effects.

This medication may increase your threat of having a cardiac arrest or stroke. This is most likely in individuals that already have cardiovascular disease or in individuals who utilize this medicine for a very long time.

This medication may cause blood loss in your belly or intestinal tracts. These problems can occur without caution indications. This is most likely if you have had a stomach ulcer in the past, if you smoke or drink alcohol on a regular basis, are over 60 years of age, are in poor health and wellness, or are using specific medications (eg, steroid medicine, blood thinner).

Contact your physician today if you have pain or tenderness in the top stomach, pale feceses, dark urine, loss of appetite, queasiness, vomiting, or yellow eyes or skin. These might be symptoms of a major liver trouble.

Serious skin reactions, consisting of Stevens-Johnson disorder, exfoliative dermatitis, harmful epidermal necrolysis, and medicine reaction with eosinophilia and systemic symptoms (DRESS) can happen throughout therapy with this medicine. Get in touch with your physician right away if you have black, tarry feceses, blistering, peeling off, or helping to loosen of the skin, upper body pain, cools, cough, diarrhea, high temperature, itching, joint or muscular tissue discomfort, excruciating or tough peeing, red irritated eyes, red skin lesions, aching throat, sores, abscess, or white places in the mouth or on the lips, swollen glands, unusual bleeding or bruising, or uncommon exhaustion or weak point.

Some possible indication of major adverse effects that can happen during therapy with this medication might include black, tarry stools, lowered urination, serious stomach discomfort, skin rash, swelling of the face, fingers, feet, or reduced legs, uncommon blood loss or discoloration, uncommon weight gain, throwing up of blood or material that appears like coffee grounds, or yellow skin or eyes. Also, indications of severe heart issues might occur, including chest pain or rigidity, rapid or irregular heart beat, unusual flushing or heat of the skin, weakness, or slurring of speech. Check with your physician immediately if you discover any of these warning signs.

Get in touch with your medical professional today if you have bloody urine, a reduction in regularity or quantity of pee, a boost in blood pressure, increased thirst, anorexia nervosa, reduced back or side discomfort, nausea, swelling of the face, fingers, or reduced legs, trouble breathing, uncommon tiredness or weakness, throwing up, or weight gain. These can be signs and symptoms of a serious kidney issue.

Hyperkalemia (high potassium in the blood) may happen while you are utilizing this medication. Get in touch with your doctor as soon as possible if you have stomach pain, confusion, difficulty with breathing, uneven heartbeat, nausea or vomiting or throwing up, anxiousness, feeling numb or prickling in the hands, feet, or lips, or weak point or thickness of the legs.

This medicine might create a serious allergic reaction called anaphylaxis, which can be lethal and needs instant clinical focus. It may take place frequently in people that dislike aspirin or other nonsteroidal anti-inflammatory medicines. Call your physician today if you have a breakout, itching, difficulty breathing or ingesting, or any swelling of your hands, face, or mouth while you are using this medicine.

Utilizing this medication throughout the later component of maternity can hurt your expected child. If you believe you have actually become pregnant while utilizing the medicine, inform your medical professional immediately.

Utilizing excessive of Cambia ® or any type of other migraine medicines (eg, ergotamine, triptans, opioids, NSAIDs, or a mix treatment for 10 or more days per month) might intensify your frustration. Speak to your physician concerning this threat. It may likewise be helpful to note of how frequently your migraine headache attacks happen and just how much medications you utilize.

Call your physician immediately if you have confusion, drowsiness, fever, basic sensation of disease, headache, anorexia nervosa, queasiness, rigid neck or back, or vomiting. These might be signs and symptoms of meningitis.

Talk to your medical professional quickly if obscured vision, trouble in analysis, or any other modification in vision takes place throughout or after your treatment. Your doctor might want you to have your eyes inspected by an ophthalmologist (optometrist).

This medicine may trigger a hold-up in ovulation for women and may impact their capacity to have children. If you prepare to have kids, talk with your doctor before utilizing this medicine.

Prior to having any type of sort of surgical procedure or medical examinations, tell your physician that you are utilizing this medicine. It may be necessary for you to quit therapy for some time, or to transform to a various nonsteroidal antiinflammatory medicine before your treatment.

Do not take other medicines unless they have actually been gone over with your doctor. This includes prescription or nonprescription (over-the-counter [OTC] medications and natural or vitamin supplements.

In deciding to use a medicine, the risks of taking the medication should be considered versus the great it will certainly do. This is a choice you and your medical professional will certainly make. For this medicine, the complying with ought to be taken into consideration:

Allergies

Inform your medical professional if you have actually ever before had any kind of uncommon or allergy to this medication or any type of various other medicines. Also tell your health care professional if you have any other sorts of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or plan ingredients very carefully.

Pediatric

Suitable studies have actually not been performed on the relationship old to the impacts of diclofenac in the pediatric populace. Safety and security and effectiveness have not been established.

Proper researches carried out to date have actually not shown pediatric-specific problems that would limit the usefulness of Zipsor ® capsules in children 12 to 17 years of age. Safety and efficiency have actually been developed.

Geriatric

Appropriate research studies performed to date have not shown geriatric-specific issues that would certainly restrict the effectiveness of diclofenac in the senior. However, senior individuals are more likely to have age-related kidney or belly issues, which may need care for clients getting diclofenac.

Breast Feeding

There are no appropriate studies in females for establishing infant risk when utilizing this medication throughout breastfeeding. Consider the prospective advantages versus the potential risks prior to taking this medication while breastfeeding.

Interactions with Medicines

Although specific medicines need to not be utilized together in any way, in various other cases 2 various medications may be used together also if an interaction might happen. In these instances, your physician might wish to transform the dose, or various other preventative measures may be needed. When you are taking this medication, it is particularly important that your healthcare specialist recognize if you are taking any one of the medications listed below. The following communications have actually been chosen on the basis of their potential importance and are not necessarily complete.

Using this medication with any of the following medicines is not recommended. Your physician may determine not to treat you with this medicine or alter a few of the other medications you take.

• Ketorolac

Using this medicine with any of the following medications is generally not recommended, yet may be required sometimes. If both medicines are suggested with each other, your doctor may transform the dosage or how usually you utilize one or both of the medications.

• Abciximab
• Acenocoumarol
• Amiloride
• Amineptine
• Amitriptyline
• Amitriptylinoxide
• Amoxapine
• Anagrelide
• Apixaban
• Ardeparin
• Argatroban
• Aspirin
• Bemetizide
• Bemiparin
• Bendroflumethiazide
• Benzthiazide
• Betamethasone
• Betrixaban
• Bivalirudin
• Budesonide
• Bumetanide
• Cangrelor
• Capecitabine
• Ceritinib
• Certoparin
• Chlorothiazide
• Chlorthalidone
• Cilostazol
• Citalopram
• Clomipramine
• Clopamide
• Clopidogrel
• Cortisone
• Cyclopenthiazide
• Cyclosporine
• Cyclothiazide
• Dabigatran Etexilate
• Dalteparin
• Danaparoid
• Deferiprone
• Deflazacort
• Desipramine
• Desirudin
• Desmopressin
• Desvenlafaxine
• Dexamethasone
• Dexketoprofen
• Diazoxide
• Dibenzepin
• Diflunisal
• Digoxin
• Dipyridamole
• Dipyrone
• Dothiepin
• Doxepin
• Droxicam
• Duloxetine
• Edoxaban
• Emtricitabine
• Enoxaparin
• Eplerenone
• Epoprostenol
• Eptifibatide
• Escitalopram
• Ethacrynic Acid
• Etodolac
• Etofenamate
• Etoricoxib
• Etozolin
• Felbinac
• Fenoprofen
• Fepradinol
• Feprazone
• Feverfew
• Floctafenine
• Flufenamic Acid
• Fluocortolone
• Fluoxetine
• Flurbiprofen
• Fluvoxamine
• Fondaparinux
• Furosemide
• Ginkgo
• Gossypol
• Heparin
• Hydrochlorothiazide
• Hydrocortisone
• Hydroflumethiazide
• Ibuprofen
• Iloprost
• Imipramine
• Indapamide
• Inotersen
• Ketoprofen
• Lepirudin
• Levoketoconazole
• Levomilnacipran
• Lithium
• Lofepramine
• Lornoxicam
• Loxoprofen
• Lumiracoxib
• Magnesium Salicylate
• Mavacamten
• Meadowsweet
• Meclofenamate
• Mefenamic Acid
• Melitracen
• Meloxicam
• Melphalan
• Mesalamine
• Methotrexate
• Methyclothiazide
• Methylprednisolone
• Metolazone
• Milnacipran
• Morniflumate
• Nabumetone
• Nadroparin
• Naproxen
• Nefazodone
• Nepafenac
• Niflumic Acid
• Nimesulide
• Nimesulide Beta Cyclodextrin
• Nortriptyline
• Olsalazine
• Opipramol
• Oxaprozin
• Oxyphenbutazone
• Paramethasone
• Parecoxib
• Parnaparin
• Paroxetine
• Pemetrexed
• Pentosan Polysulfate Sodium
• Pentoxifylline
• Phenindione
• Phenprocoumon
• Phenylbutazone
• Phenyl Salicylate
• Piketoprofen
• Piretanide
• Piroxicam
• Polythiazide
• Potassium Citrate
• Prasugrel
• Prednisolone
• Prednisone
• Proglumetacin
• Propyphenazone
• Proquazone
• Protein C.
• Protriptyline.
• Quinethazone.
• Reviparin.
• Rivaroxaban.
• Rofecoxib.
• Salicylamide.
• Salicylic Acid.
• Salsalate.
• Selexipag.
• Sertraline.
• Sibutramine.
• Sodium Salicylate.
• Sparsentan.
• Spironolactone.
• Sulfasalazine.
• Sulfinpyrazone.
• Sulindac.
• Sulodexide.
• Tacrolimus.
• Tenofovir Alafenamide.
• Tenofovir Disoproxil Fumarate.
• Tenoxicam.
• Tianeptine.
• Tiaprofenic Acid.
• Ticagrelor.
• Ticlopidine.
• Tinzaparin.
• Tirofiban.
• Tolfenamic Acid.
• Tolmetin.
• Torsemide.
• Trazodone.
• Treprostinil.
• Triamterene.
• Trichlormethiazide.
• Trimipramine.
• Trolamine Salicylate.
• Valdecoxib.
• Venlafaxine.
• Vilazodone.
• Vorapaxar.
• Vortioxetine.
• Warfarin.
• Xipamide.

Using this medicine with any one of the complying with medications may trigger an enhanced threat of specific side effects, yet using both drugs might be the most effective therapy for you. If both medications are recommended together, your doctor may change the dose or exactly how typically you use one or both of the medications.

• Acebutolol.
• Atenolol.
• Azilsartan.
• Azilsartan Medoxomil.
• Benazepril.
• Betaxolol.
• Bisoprolol.
• Candesartan.
• Captopril.
• Carteolol.
• Carvedilol.
• Celiprolol.
• Cholestyramine.
• Ciprofloxacin.
• Colestipol.
• Enalapril.
• Enalaprilat.
• Eprosartan.
• Esmolol.
• Fosinopril.
• Irbesartan.
• Labetalol.
• Levobunolol.
• Lisinopril.
• Losartan.
• Metipranolol.
• Metoprolol.
• Moexipril.
• Nadolol.
• Nebivolol.
• Olmesartan.
• Oxprenolol.
• Penbutolol.
• Perindopril.
• Pindolol.
• Propranolol.
• Quinapril.
• Ramipril.
• Sotalol.
• Spirapril.
• Telmisartan.
• Timolol.
• Trandolapril.
• Valsartan.

Interactions with Food/Tobacco/Alcohol.

Specific medicines should not be utilized at or around the moment of eating food or consuming particular kinds of food because communications may take place. Utilizing alcohol or cigarette with specific medicines may likewise create interactions to happen. Talk about with your health care specialist using your medicine with food, alcohol, or cigarette.

Other Medical Problems.

The existence of other clinical issues may impact making use of this medicine. Make certain you inform your doctor if you have any various other clinical troubles, specifically:.

• Allergy to bovine healthy protein-- Zipsor ® capsule has gelatin and needs to not be made use of in clients with this problem.

• Anemia or.
• Bleeding issues or.
• Blood embolisms or.
• Congestive heart failure or.
• Edema (liquid retention) or.
• Heart attack, history of or.
• Heart disease or.
• Hypertension (high blood pressure) or.
• Kidney condition or.
• Porphyria (blood problem) or.
• Stomach ulcers or blood loss, history of or.
• Stroke, history of-- Use with care. May make these problems worse.

• Aspirin-sensitive asthma, background of or.
• Aspirin (or various other NSAIDs) level of sensitivity, background of or.
• Kidney disease, extreme-- Should not be made use of in clients with these conditions.

• Dehydration or.
• Hypovolemia-- Must be corrected first before using this medicine.

• Heart surgical treatment (eg, coronary artery bypass graft [CABG] surgery)-- Should not be used to eliminate discomfort right prior to or after the surgery.

• Liver illness-- Use with care. The effects might be raised because of slower elimination of the medication from the body.

Together with its required effects, a medicine may create some unwanted impacts. Although not all of these side effects might happen, if they do occur they might need medical interest.

Get in touch with your physician immediately if any of the following negative effects take place:

Extra typical

• Acid or sour tummy
• burping
• hemorrhaging periodontals
• blood in the pee or stools
• bloody or black, tarry stools
• melting while urinating
• upper body pain
• chills
• cough
• clay-colored stools
• over cast urine
• bowel irregularity
• dark pee
• decrease in pee outcome or decrease in urine-concentrating ability
• looseness of the bowels
• lightheadedness
• feeling of acid indigestion
• fever
• frequent urge to urinate
• headache
• heartburn
• enhanced bleeding time
• acid indigestion
• itching skin or breakout
• light-colored stools
• loss of appetite
• nausea or vomiting and vomiting
• pain in the breast listed below the breastbone
• uncomfortable or difficult urination
• pale skin
• determine red areas on the skin
• belly bloating, burning, cramping, discomfort, dismayed, or discomfort
• aching throat
• sores, ulcers, or white areas on the lips or in the mouth
• swelling or swelling of the mouth
• swollen glands
• problem breathing
• unpleasant breath smell
• unusual bleeding or wounding
• uncommon fatigue or weak point
• top best abdominal or stomach pain
• vomiting of blood or material that appears like coffee premises
• fat burning
• yellow eyes and skin

Less usual

• Blistering, peeling off, loosening up of the skin
• obscured vision
• burning, creeping, itching, pins and needles, tingling, "pins and needles", or tingling feelings
• confusion
• modification in consciousness
• frustration
• dizziness, faintness, or impaired thinking when standing up unexpectedly from a lying or resting position
• feeling of consistent motion of self or surroundings
• sensation sad or empty
• irritation
• joint or muscle pain
• absence of cravings
• absence or loss of toughness
• loss of awareness
• loss of passion or enjoyment
• nervousness
• discomfort or pain in the arms, jaw, back, or neck
• pale or blue lips, finger nails, or skin
• red inflamed eyes
• red skin sores, usually with a purple facility
• redness, pain, or itching skin
• sensation of spinning
• restlessness in the legs, arms, hands, or feet
• sleepiness or uncommon drowsiness
• tight neck or back
• shivering or drinking of the hands or feet
• difficulty concentrating
• difficulty resting

Get emergency situation assistance instantly if any one of the adhering to symptoms of overdose happen:

Signs and symptoms of overdose

• Agitation
• obscured vision
• modification in awareness
• modification in the capability to see colors, specifically blue or yellow
• complication
• anxiety
• tough or difficulty breathing
• hives
• hostility
• uneven, rapid or sluggish, or shallow breathing
• irritation
• loss of consciousness
• muscular tissue twitching
• anxiousness
• discomfort or discomfort in the upper body, upper belly, or throat
• pale or blue lips, fingernails, or skin
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• rapid weight gain
• seizures
• sleepiness
• sluggish or rapid heart beat
• amazement
• swelling of the face, ankle joints, or hands
• tightness in the chest
• difficulty resting
• unusual drowsiness, monotony, or feeling of sluggishness

Some adverse effects may take place that usually do not require clinical focus. These side effects might go away throughout treatment as your body adjusts to the medication. Additionally, your health care expert might have the ability to tell you regarding means to stop or decrease some of these side effects. Check with your healthcare professional if any one of the following side effects proceed or are annoying or if you have any kind of inquiries about them:

Much more common

• Bloated
• proceeding buzzing or humming or other inexplicable sound in the ears
• difficulty in ingesting
• excess air or gas in the belly or intestinal tracts
• hearing loss
• absence or loss of stamina
• pain or burning in the throat
• passing gas

Less common

• Burning, completely dry or itching eyes
• discharge, excessive tearing
• loss of hair, thinning of the hair
• raised level of sensitivity of the skin to sunshine
• discomfort in the arms or legs
• redness, pain, swelling of the eye, eyelid, or internal lining of eyelid
• inflammation or other staining of the skin
• severe sunburn

Opposite results not detailed may also occur in some individuals. If you notice any other impacts, consult your medical care expert.

Call your doctor for clinical recommendations regarding side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Cambia
• Cataflam
• Voltaren
• Voltaren-XR
• Zipsor
• Zorvolex

Offered Dosage Forms:

• Capsule
• Tablet, Enteric Coated
• Tablet, Extended Release
• Tablet
• Powder for Solution
• Capsule, Liquid Filled

Restorative Class: Central Nervous System Agent

Pharmacologic Class: NSAID

Chemical Class: Acetic Acid (class).

Keep using this medicine for the full time of treatment. However, do not use this medicine more often or for a longer time than your doctor ordered. This medicine is not for long-term use.

This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

When used for severe or continuing arthritis, this medicine must be taken every day as ordered by your doctor in order for it to help you. This medicine usually begins to work within one week, but in severe cases up to two weeks or longer may pass before you begin to feel better. Several weeks may pass before you feel the full effects of this medicine.

You may take this medicine with or without food. However, diclofenac capsules should be taken on an empty stomach.

To use the oral solution:

• Open the packet of medicine right before you use it.
• Empty the contents of the packet into a cup with 1 to 2 ounces (30 to 60 milliliters [mL]) of water. Do not use any liquid other than water for mixing the medicine.
• Mix well and drink it immediately on an empty stomach.

Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (Zipsor® capsules):For acute pain: Adults and children 12 years of age and older—25 milligrams (mg) 4 times a day. Children younger than 12 years of age—Use and dose must be determined by your doctor.
• For oral dosage form (Zorvolex® capsules): For acute pain: Adults—18 or 35 milligrams (mg) 3 times a day. Children—Use and dose must be determined by your doctor. For osteoarthritis: Adults—35 milligrams (mg) 3 times a day. Children—Use and dose must be determined by your doctor.
• For oral dosage forms (delayed-release tablets, enteric-coated tablets): For ankylosing spondylitis: Adults—25 milligrams (mg) 4 times a day, with an extra 25 mg dose at bedtime if necessary. Children—Use and dose must be determined by your doctor. For osteoarthritis: Adults—50 milligrams (mg) 2 or 3 times a day, or 75 mg two times a day. Children—Use and dose must be determined by your doctor. For rheumatoid arthritis: Adults—50 milligrams (mg)3 or 4 times a day, or 75 mg two times a day. Children—Use and dose must be determined by your doctor.
• For oral dosage form (immediate-release tablets): For osteoarthritis: Adults—50 milligrams (mg) 2 or 3 times a day. Children—Use and dose must be determined by your doctor. For pain or menstrual cramps: Adults—50 milligrams (mg) 3 times a day. Your doctor may direct you to take 100 mg for the first dose only. Children—Use and dose must be determined by your doctor. For rheumatoid arthritis: Adults—50 milligrams (mg) 3 or 4 times a day. Children—Use and dose must be determined by your doctor.
• For oral dosage form (solution):For migraine headaches: Adults—One packet (50 milligrams) as a single, one time dose. Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

• Can I take ibuprofen with blood pressure medications?
• Why is diclofenac prescription only but ibuprofen is OTC?
• Can you Double up on Pain Meds? Safe Painkiller Combinations
• Does diclofenac contain narcotics or affect a drug test?
• Which painkiller should you use?
• Can NSAIDs be used to treat a COVID-19 fever?

View more FAQ