Von Willebrand factor (recombinant)

Von Willebrand factor is a naturally occurring healthy protein in the blood that helps blood to clot. People with an inherited blood-clotting condition called von Willebrand disease do not have enough of this protein in their blood. An absence of von Willebrand factor can cause unrestrained bleeding.

Von Willebrand factor is utilized to control bleeding episodes in grownups with von Willebrand disease.

Von Willebrand factor may also be used for purposes not provided in this medication overview.

Von Willebrand factor is infused into a capillary via an IV. You might be demonstrated how to make use of an IV in your home. Do not provide yourself this medication if you do not recognize exactly how to utilize the shot and properly deal with needles, IV tubing, and other products made use of.

Check out all person info, drug overviews, and guideline sheets offered to you. Ask your physician or pharmacologist if you have any type of questions.

Von Willebrand factor is a powder medication that need to be blended with a fluid (diluent) before using it. If you are making use of the injections in the house, make sure you understand exactly how to properly blend and store the medicine. Mixed medicine has to be utilized within 3 hours if you maintain it at space temperature.

Do not tremble the combined medicine. Prepare your dose just when you are ready to provide an injection.

Do not utilize the medicine if it looks gloomy or has particles in it. Call your pharmacist for new medicine.

Tell your doctor if you have any changes in weight. Von Willebrand factor dosages are based upon weight, and any adjustments may impact the dose.

You may need regular medical tests to help your doctor establish how long to treat you with von Willebrand factor.

Utilize a disposable needle and syringe only when. Follow any state or neighborhood legislations concerning discarding used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacologist where to obtain one and exactly how to toss it away). Maintain this container out of the reach of youngsters and animals.

Shop this medicine in its original container in a fridge till you prepare to prepare your dose. Do not allow the to medicine freeze.

You might additionally save the container at room temperature for up to 12 months.

Do not utilize this medicine if the expiration day on the tag has passed.

Comply with all directions on your medicine tag and plan. Inform each of your healthcare providers regarding all your clinical problems, allergies, and all medicines you utilize.

You should not use von Willebrand factor if you have ever before had an extreme allergy to von Willebrand factor, or if you are allergic to computer mice or hamsters.

To ensure von Willebrand factor is safe for you, tell your medical professional if you have ever been told that you have:

• inhibitors to von Willebrand factor; or
• inhibitors to blood coagulation factor VIII.

It is not understood whether this medication will certainly damage an unborn infant. Inform your medical professional if you are pregnant or plan to conceive.

It is not known whether von Willebrand factor passes into bust milk or if it can influence the nursing baby. Inform your physician if you are breast-feeding.

Get emergency clinical aid if you have indications of an allergic reaction: hives, itching; rigidity in your throat or chest, difficult breathing; swelling of your face, lips, tongue, or throat.

Von Willebrand factor may cause serious side effects. Call your medical professional at once if you have:

• abrupt tingling or weak point (particularly on one side of the body);.
• chest pain or pressure, sudden coughing, hissing, quick breathing, coughing up blood;.
• pain, swelling, heat, or soreness in one or both legs;.
• queasiness; or.
• a light-headed sensation, like you could lose consciousness.

Common side effects of von Willebrand factor might include:.

• a burning sensation around the IV needle;.
• lightheadedness, nausea or vomiting;.
• muscular tissue twitching;.
• unusual or undesirable taste in the mouth;.
• hot flashes;.
• quick heart rate;.
• irritation;.
• upper body discomfort; or.
• boosted high blood pressure.

This is not a full listing of side effects and others might happen. Call your medical professional for clinical advice concerning negative effects. You may report negative effects to FDA at 1-800-FDA-1088.

Given that von Willebrand factor is made use of when required, it does not have a day-to-day dosing timetable. Call your medical professional immediately if your signs do not improve after utilizing von Willebrand factor.

Seek emergency situation clinical focus or call the Toxin Customer service at 1-800-222-1222.

Follow your doctor's directions concerning any kind of constraints on food, beverages, or task.

Other drugs might interact with von Willebrand factor, consisting of prescription and over-the-counter medications, vitamins, and herbal products. Inform each of your health care suppliers about all medicines you make use of currently and any type of medication you begin or stop utilizing.