Vumon (Intravenous)

Teniposide shot is made use of in combination with various other medications to deal with severe lymphoblastic leukemia (ALL).

Teniposide belongs to the team of medicines known as antineoplastic agents. It hinders the development of the cancer cells, which are ultimately ruined. Given that the development of normal body cells may also be impacted by teniposide, other effects will additionally take place. Some of these may be severe and must be reported to your physician. Various other results, like hair loss, may not be significant however might cause problem. Some results may not happen till months or years after the medicine is made use of.

Prior to you begin treatment with teniposide, you and your medical professional ought to talk about the benefits of this medicine as well as the risks of using it.

This medicine is to be carried out only by or under the prompt supervision of your medical professional.

It is very vital that your medical professional inspect your progress at routine visits to ensure that this medicine is working effectively. Blood tests might be needed to check for undesirable effects.

This medicine might trigger a significant type of allergic reaction called anaphylaxis. Anaphylaxis can be serious and needs prompt clinical attention. Tell your medical professional or nurse right away if you have cools; fever; impaired thinking, dizziness, or fainting; quick, pounding heart beat; swelling of the face, tongue, and throat; or problem with breathing after you receive the medicine.

If teniposide accidentally leaks out of the vein into which it is injected, it may harm some cells and may create scarring. Tell the physician right away if you notice inflammation, discomfort, or swelling at the shot website.

While you are being treated with teniposide, and after you stop treatment, do not have any type of booster shots (inoculations) without your doctor's authorization. Teniposide may decrease your body's resistance, and there is a chance you may get the infection the booster shot is implied to stop. Furthermore, various other persons staying in your family should not take dental polio vaccine, considering that there is a chance they might pass the polio virus on you. Likewise, avoid individuals that have taken dental polio vaccination within the last several months. Do not get near them, and do not stay in the very same area with them for very long. If you can not take these preventative measures, you need to take into consideration putting on a safety face mask that covers the nose and mouth.

This medicine can cause abnormality if it is made use of by the mom while she is expectant or by the daddy when his sexual companion becomes pregnant. Utilize a reliable form of contraception to keep from getting pregnant. If a pregnancy takes place while you are using this medication, tell your medical professional right now.

This medication might trigger a decline in the amount of sperm you have an orgasm throughout sex. This might affect your ability to have youngsters. Ask your physician on whether you can store sperm for future artificial use.

Hypotension (low blood pressure) might accompany this medicine. Your physician will gauge your high blood pressure and keep it from going too low while you are getting this medicine.

Teniposide can briefly decrease the variety of white blood cells in your blood, raising the chance of getting an infection. It can additionally decrease the variety of platelets, which are required for appropriate blood clotting. If this takes place, there are particular preventative measures you can take, specifically when your blood matter is reduced, to reduce the danger of infection or blood loss:

• If you can, avoid individuals with infections. Contact your physician promptly if you assume you are obtaining an infection or if you get a fever or chills, coughing or hoarseness, lower back or side discomfort, or unpleasant or hard urination.
• Check with your doctor instantly if you see any type of unusual blood loss or bruising; black, tarry stools; blood in pee or stools; or determine red spots on your skin.
• Be careful when using a routine toothbrush, floss, or toothpick. Your medical professional might show you other methods to cleanse your teeth and gum tissues. Check with your clinical doctor before having any type of dental work done.
• Do not touch your eyes or the inside of your nose unless you have actually just cleaned your hands and have not touched anything else in the meantime.
• Be mindful not to reduce on your own when you are using sharp things such as a safety razor or fingernail or toenail cutters.
• Avoid call sporting activities or other scenarios where discoloration or injury could happen.

In determining to make use of a medicine, the risks of taking the medicine should be evaluated versus the excellent it will certainly do. This is a decision you and your physician will make. For this medication, the complying with ought to be taken into consideration:

Allergies

Inform your medical professional if you have ever had any kind of uncommon or allergic reaction to this medicine or any kind of various other medications. Likewise inform your health care expert if you have any kind of various other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription items, reviewed the tag or bundle components meticulously.

Pediatric

Proper studies performed to day have not shown pediatric-specific troubles that would certainly limit the usefulness of teniposide injection in children.

Geriatric

No details is available on the relationship of age to the impacts of teniposide injection in senior citizen patients. Nonetheless, elderly individuals are more likely to have undesirable adverse effects (e.g., hypotension or reduced blood pressure), which may need caution in patients receiving teniposide injection.

Breast Feeding

There are no sufficient studies in ladies for establishing baby threat when using this drug during breastfeeding. Weigh the possible benefits against the possible risks prior to taking this medication while breastfeeding.

Interactions with Medicines

Although particular medicines need to not be made use of together in any way, in various other instances two different medications might be used together also if a communication may take place. In these cases, your physician might want to alter the dosage, or various other preventative measures might be needed. When you are taking this medicine, it is particularly essential that your medical care expert know if you are taking any of the medications listed below. The complying with communications have been picked on the basis of their prospective value and are not necessarily all-inclusive.

Utilizing this medication with any of the complying with medications is not recommended. Your physician might decide not to treat you with this medication or transform a few of the various other medicines you take.

• Measles Virus Vaccine, Live
• Mumps Virus Vaccine, Live
• Rotavirus Vaccine, Live
• Rubella Virus Vaccine, Live
• Varicella Virus Vaccine, Live
• Zoster Vaccine, Live

Using this medicine with any one of the complying with medicines is typically not suggested, but may be required in some cases. If both medicines are recommended together, your doctor might change the dose or just how typically you make use of one or both of the medicines.

• Adenovirus Vaccine
• Bacillus of Calmette and Guerin Vaccine, Live
• Cholera Vaccine, Live
• Dengue Tetravalent Vaccine, Live
• Glucosamine
• Influenza Virus Vaccine, Live
• Phenobarbital
• Poliovirus Vaccine, Live
• Smallpox Vaccine
• Typhoid Vaccine, Live
• Yellow Fever Vaccine

Interactions with Food/Tobacco/Alcohol

Specific medicines ought to not be made use of at or around the moment of eating food or consuming particular sorts of food given that interactions may happen. Utilizing alcohol or cigarette with specific medicines may likewise create communications to take place. Discuss with your healthcare specialist making use of your medicine with food, alcohol, or cigarette.

Other Medical Problems

The existence of other medical issues might influence the use of this medicine. Ensure you tell your medical professional if you have any type of various other medical troubles, especially:

• Blood conditions as a result of bone marrow depression or
• Infection-- There may be an enhanced danger of infections or intensifying infections as a result of the body's minimized ability to fight them.

• Central nerves (CNS) anxiety or
• Chickenpox (including current exposure) or
• Herpes zoster (tiles) or
• Hypotension (reduced high blood pressure) or
• Metabolic acidosis-- Use with care. May make these conditions worse.

• Down syndrome-- Patients who have this condition might be a lot more conscious this medicine. Dosage may be readjusted.

• Hypoalbuminemia (low albumin in the blood) or
• Kidney illness or
• Liver disease-- Use with caution. The effects may be increased due to slower removal of the medication from the body.

Together with its needed results, a medication might trigger some undesirable results. Although not all of these adverse effects might take place, if they do happen they may need clinical interest.

Contact your physician immediately if any of the adhering to negative effects take place:

Extra typical

• Black, tarry stools
• blood in urine or stools
• chills
• coughing or hoarseness
• fever
• hives
• lower back or side pain
• uncomfortable or challenging urination
• pinpoint red places on skin
• shortness of breath
• rigidity in chest or hissing
• bothered breathing
• unusual blood loss or bruising

Get in touch with your physician immediately if any of the adhering to negative effects happen:

Much more typical

• Flushing of face
• sores in mouth or on lips
• abnormally rapid heartbeat
• unusual fatigue

Much less common

• Skin breakout

Unusual

• Decreased urination
• swelling of face, fingers, feet, or reduced legs
• yellow eyes or skin

Some negative effects might take place that usually do not require clinical interest. These side effects may go away throughout treatment as your body adapts to the medicine. Likewise, your health care professional may have the ability to tell you concerning methods to prevent or reduce a few of these side effects. Check with your healthcare expert if any one of the complying with side effects continue or are irritating or if you have any kind of questions concerning them:

Extra common

• Diarrhea
• queasiness and throwing up

This medicine often creates a short-lived hair loss. After treatment with teniposide has actually ended, normal hair growth must return.

Opposite impacts not listed might also take place in some people. If you see any kind of various other effects, get in touch with your medical care professional.

Call your medical professional for clinical guidance concerning side effects. You may report adverse effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Vumon

Offered Dosage Forms:

• Solution

Healing Class: Antineoplastic Agent

Pharmacologic Class: Mitotic Inhibitor

A doctor or other trained health professional will give you this medicine in a hospital or cancer treatment center. This medicine is given through a needle placed in one of your veins. This medicine must be given slowly, so the IV tube must remain in place for at least 30 to 60 minutes.

Teniposide is sometimes given together with other medicines. If you are receiving a combination of medicines, it is important that you receive each one at the proper time. If you are taking some of these medicines by the mouth, ask your doctor to help you plan a way to take them at the right times.

Teniposide often causes nausea, vomiting, and loss of appetite, which may be severe. However, it is very important that you continue to receive the medicine, even if you begin to feel ill. Ask your doctor for ways to lessen these effects.

You may also receive other medicines to help prevent nausea or vomiting and allergic reactions from teniposide.