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Vyxeos (liposomal)
Generic name: cytarabine and daunorubicin (liposomal)
Brand names: Vyxeos
What is Vyxeos liposomal?
Vyxeos is a combination medication utilized to deal with acute myeloid leukemia that is recently diagnosed in adults and children a minimum of 1 years of age.
Vyxeos might likewise be used for purposes not listed in this drug guide.
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Warnings
Vyxeos can make it simpler for you to bleed. Call your physician or look for emergency medical interest if you have simple discoloration, uncommon blood loss, or any kind of bleeding that will certainly not stop. You might likewise have hemorrhaging on the inside of your body, such as in your stomach or intestines, or in your brain.
Call your medical professional at the same time if you have: indicators of blood loss in your digestion tract-- sensation very weak or woozy, severe tummy discomfort, black or bloody stools, or if you spend blood or vomit that resembles coffee premises; or signs of bleeding in the mind-- abrupt pins and needles or weakness (particularly on one side of the body), sudden serious frustration, or issues with vision or balance.
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Before taking this medicine
You must not be treated with this medicine if you dislike cytarabine or daunorubicin.
Tell your doctor if you have actually ever before had:
- heart disease;
- liver or kidney disease;
- radiation therapy of your upper body area; or
- Wilson's illness (a rare genetic disorder).
You may require to have a negative maternity examination before beginning this therapy.
Both males and females using this medication needs to use efficient birth control to avoid maternity. Vyxeos can damage an expected child if the mother or father is using this medication.
Maintain making use of contraception for at the very least 6 months after your last dose. Tell your medical professional as soon as possible if a pregnancy takes place while either the mommy or the daddy is using this medication.
It may be harder for you to get a female expecting while you are utilizing this medicine. You must still utilize contraception to avoid pregnancy since the medicine can harm an expected baby.
You ought to not nurse while utilizing this medication and for at the very least 2 weeks after your last dose.
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Vyxeos liposomal side effects
Get emergency situation medical assistance if you have indicators of an allergy: hives; tough breathing; swelling of your face, lips, tongue, or throat.
Vyxeos can make it much easier for you to bleed. Call your doctor or look for emergency situation medical interest if you have:
- easy bruising, uncommon bleeding (nose, mouth, vaginal area, anus), or any bleeding that will not quit;
- indicators of bleeding in your digestive tract-- feeling extremely weak or lightheaded, severe stomach pain, black or bloody feceses, spending blood or vomit that resembles coffee premises; or
- indications of blood loss in the mind-- abrupt tingling or weak point (especially on one side of the body), sudden serious migraine, issues with vision or balance.
Vyxeos may create significant side effects. Call your physician simultaneously if you have:
- severe or ongoing diarrhea;
- sores or white patches in or around your mouth, trouble swallowing or speaking, dry mouth, foul breath, modified sense of taste;
- fast, slow, or irregular heart rate;
- discomfort, burning, inflammation, or skin changes where the shot was given;
- heart problems-- swelling, rapid weight gain, feeling breathless; or
- signs of infection-- high temperature, cools, inflamed periodontals, skin sores, chilly or flu signs and symptoms, cough with mucus, breast pain, hissing, problem breathing, quick heart price, fainting.
Your cancer cells treatments may be postponed or permanently discontinued if you have certain side effects.
Usual adverse effects of Vyxeos may include:
- blood loss (especially nosebleeds);.
- fever, chills;.
- irregular heartbeats;.
- queasiness, throwing up, belly pain, loss of appetite;.
- diarrhea, bowel irregularity;.
- mouth sores;.
- cough, problem breathing;.
- breakout;.
- muscle or joint pain;.
- migraine, really feeling tired;.
- swelling anywhere in your body; or.
- rest problems (insomnia).
This is not a complete listing of negative effects and others may happen. Call your doctor for clinical guidance concerning negative effects. You may report side effects to FDA at 1-800-FDA-1088.
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How is Vyxeos liposomal given?
The liposomal combination of cytarabine and daunorubicin is not given in the same doses or on the same schedule as other forms of cytarabine or daunorubicin. If you have used either of these medicines before, your dose schedule of cytarabine and daunorubicin liposomal may be different.
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using Vyxeos.
Vyxeos is given as an infusion into a vein. A healthcare provider will give you this injection.
This medicine must be given slowly, and the infusion can take at least 90 minutes to complete.
Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when the medicine is injected.
Vyxeos is usually given every other day for up to 3 infusions in a 5-day treatment cycle. If you need additional treatment cycles, you will need to wait 5 to 8 weeks before you receive the medicine again.
You may be given other medications to help prevent serious side effects or allergic reaction. Keep taking these medicines for as long as your doctor has prescribed.
Vyxeos doses are based on body surface area (height and weight). Your dose needs may change if you gain or lose weight or if you are still growing.
Your doctor will determine how long to treat you with this medicine.
This medicine can make it easier for you to bleed. Contact your doctor or seek emergency medical attention if you have easy bruising, unusual bleeding, or any bleeding that will not stop.
What happens if I miss a dose?
Call your medical professional for instructions if you miss out on a visit for your Vyxeos liposomal shot.
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What happens if I overdose?
Look for emergency situation medical interest or call the Poison Customer service at 1-800-222-1222.
Follow your physician's guidelines about any type of limitations on food, beverages, or task.
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What other drugs will affect Vyxeos liposomal?
Other medicines might impact Vyxeos, consisting of prescription and over the counter medications, vitamins, and herbal items. Inform your doctor about all your current medicines and any kind of medication you begin or quit making use of.
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Frequently asked questions
- How is Vyxeos administered and how long do you take it for?
- Why does Vyxeos have a polymer coating?
- What drugs are contained in Vyxeos?
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Content is provided for education and is not medical advice. See our medical disclaimer.