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Zafirlukast
Generic name: zafirlukast
Brand names: Accolate
What is zafirlukast?
Zafirlukast is a leukotriene (loo-koe-TRY-een) inhibitor that is utilized to prevent bronchial asthma attacks in adults and kids as young as 5 years old.
Zafirlukast might additionally be made use of for objectives not provided in this drug overview.
This section was rewritten for readability and reviewed for meaning.
How should I take zafirlukast?
Follow all directions on your prescription label and review all medicine guides or instruction sheets. Make use of the medication exactly as directed.
Zafirlukast is not a fast-acting rescue medication for asthma assaults. Seek medical focus if your breathing troubles get worse rapidly, or if you believe your medications are not working.
Tackle an empty belly, a minimum of 1 hour before or 2 hours after a meal.
Your dose needs may transform because of surgical treatment, ailment, stress, or a current asthma attack. Do not alter your dose or stop making use of bronchial asthma medication without your doctor's guidance.
Keep making use of zafirlukast as routed, even if you have no bronchial asthma symptoms.
If you take dental steroid medicine, do not stop it suddenly. Ask your physician regarding tapering your dose.
Shop at area temperature level away from moisture, warm, and light. Keep the bottle tightly shut when not in use.
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Warnings
Inform your physician right now if you have indications of capillary inflammation: flu-like signs and symptoms, extreme sinus pain, a skin breakout, pins and needles or a "pins and needles" feeling in your arms or legs.
Stop taking this medicine and call your doctor right away if you have any type of uncommon adjustments in state of mind or actions (such as agitation, complication, clinical depression, sleep issues, compulsive behaviors, hallucinations, or suicidal thoughts or activities).
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Before taking this medicine
You must not make use of zafirlukast if you dislike it, or if you have liver condition (including cirrhosis).
Tell your doctor if you have ever had liver disease.
Not approved for usage by anybody younger than 5 years old.
The chewable tablet computer may consist of phenylalanine and might be hazardous if you have phenylketonuria (PKU).
It is not known if zafirlukast will certainly damage a coming baby. Tell your doctor if you are expectant or plan to become pregnant.
You ought to not nurse while utilizing zafirlukast.
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Zafirlukast side effects
Obtain emergency medical aid if you have indications of an allergic reaction: hives, sores, extreme irritation; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your doctor right away if you have signs of capillary inflammation: flu-like signs, severe sinus pain, a skin rash, tingling or a "pins and needles" feeling in your arms or legs.
Some individuals making use of zafirlukast have actually had brand-new or worsening psychological issues. Stop taking zafirlukast and call your doctor as soon as possible if you have unusual adjustments in mood or actions, such as:
- agitation, aggressiveness, feeling agitated or short-tempered;
- anxiousness, clinical depression, complication, issues with memory or attention;
- stuttering, shakes, unrestrained muscular tissue motions;
- suicidal thoughts or actions;
- hallucinations, sleep troubles, vivid desires, sleep-walking; or
- uncontrollable or repeated habits.
Additionally call your physician at the same time if you have:
- getting worse or no improvement in your asthma signs; or
- liver troubles-- nausea or vomiting, loss of appetite, tummy pain (top ideal side), fatigue, itching, dark urine, jaundice (yellowing of the skin or eyes).
Typical negative effects of zafirlukast might consist of:
- nausea or vomiting, looseness of the bowels, stomach pain;
- frustration; or
- cool signs and symptoms such as stuffy nose, sneezing, sore throat.
This is not a total list of negative effects and others may happen. Call your physician for clinical guidance about adverse effects. You may report negative effects to FDA at 1-800-FDA-1088.
This section was rewritten for readability and reviewed for meaning.
Zafirlukast dosing information
Usual Adult Dose for Asthma -- Maintenance:
-20 mg orally twice a day, 1 hour before or 2 hours after mealsComments:-A dose of 20 mg twice daily was not associated with an increase in the overall incidence of adverse events or withdrawals in elderly patients.Use: Prophylaxis and chronic treatment of asthma
Usual Pediatric Dose for Asthma -- Maintenance:
Less than 5 years: The safety and effectiveness has not been established.5 to 11 years:-10 mg orally twice a day, 1 hour before or 2 hours after meals12 years or older:-20 mg orally twice a day, 1 hour before or 2 hours after mealsUse: Prophylaxis and chronic treatment of asthma
What happens if I miss a dose?
Take the medicine as quickly as you can, however miss the missed dose if it is virtually time for your following dose. Do not take two dosages at once.
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What happens if I overdose?
Seek emergency clinical interest or call the Poisonous substance Customer service at 1-800-222-1222.
Avoid situations or activities that might activate an asthma attack.
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What other drugs will affect zafirlukast?
Tell your doctor concerning all your other medicines, particularly:
- erythromycin;
- fluconazole;
- theophylline; or
- warfarin, Coumadin, Jantoven.
This list is not full. Various other drugs might influence zafirlukast, including prescription and over the counter medicines, vitamins, and herbal products. Not all possible drug interactions are detailed here.
This section was rewritten for readability and reviewed for meaning.
Related medicines
Content is provided for education and is not medical advice. See our medical disclaimer.