On this page · 6 sections

Zapzyt (Topical)

Generic name: salicylic acid

Brand names: Akurza, Aliclen, Avosil, Betasal, Compound W, Corn Removing, Dermarest Psoriasis, DHS Sal, Drytex, Duofilm, Duoplant, Durasal, Freezone, Fung-O, Gets-It Corn/Callus Remover, Gordofilm, Hydrisalic, Ionil, Ionil Plus, Keralyt

Last updated December 24, 2025 0 views
Share

Uses for Zapzyt

Salicylic acid topical is used to treat many skin conditions, such as acne, dandruff, psoriasis, seborrheic dermatitis of the skin and scalp, calluses, corns, typical protuberances, and plantar moles, depending on the dosage form and strength of the prep work.

This medication is readily available over the counter. Some of these prep work are available just with your doctor's prescription.

This section was rewritten for readability and reviewed for meaning.

Precautions while using Zapzyt

If your signs do not boost within a few days, or if it become worse, contact your physician.

When making use of salicylic acid, do not use any one of the adhering to preparations on the same damaged area as this medicine, unless otherwise guided by your doctor:

  • Abrasive soaps or cleansers
  • Alcohol-containing preparations
  • Any various other topical acne preparation or prep work including a peeling off representative (eg, benzoyl peroxide, resorcinol, sulfur, or tretinoin [vitamin A acid]
  • Cosmetics or soaps that dry the skin
  • Medicated cosmetics
  • Other topical medicine for the skin

To utilize any one of the above preparations on the exact same affected location as salicylic acid might create severe irritation of the skin.

This medicine may cause a serious condition called salicylate toxicity. This is more probable to occur specifically in children, or if you have kidney condition or liver condition. Talk to your physician immediately if you have nausea, vomiting, lightheadedness, loss of hearing, tinnitus, sleepiness hyperpnea, looseness of the bowels, and psychic disturbances.

Particular non-prescription (OTC) acne products might trigger unusual and serious allergic reactions. Contact your doctor as soon as possible if you have hives, itching, difficulty breathing, swelling of the eyes, face, lips, or tongue, rigidity in the throat, or feeling faint while using these items.

Do not make use of an OTC acne product once more if you have developed a serious allergy from it.

This section was rewritten for readability and reviewed for meaning.

Before using Zapzyt

In choosing to utilize a medication, the threats of taking the medicine needs to be weighed against the excellent it will certainly do. This is a choice you and your medical professional will make. For this medication, the adhering to ought to be considered:

Allergies

Tell your physician if you have ever before had any unusual or allergy to this medicine or any type of other medications. Additionally inform your healthcare expert if you have any type of other sorts of allergic reactions, such as to foods, dyes, chemicals, or animals. For non-prescription items, read the tag or bundle components thoroughly.

Pediatric

Little ones may go to increased risk of unwanted results as a result of raised absorption of salicylic acid with the skin. Likewise, kids might be more likely to obtain skin irritability from salicylic acid. Salicylic acid needs to not be related to huge areas of the body, made use of for long periods of time, or used under occlusive clothing (air-tight covering, such as kitchen plastic wrap) in kids. Use salicylic acid topical in children more youthful than 2 years of age is not advised.

Geriatric

Appropriate studies performed to date have actually not shown geriatric-specific problems that would restrict the effectiveness of salicylic acid topical in the elderly. Nonetheless, senior people are most likely to have age-related capillary disease, which might require care in people getting salicylic acid topical.

Breast Feeding

There are no sufficient researches in females for establishing baby threat when using this medicine during breastfeeding. Consider the potential advantages against the potential threats prior to taking this drug while breastfeeding.

Interactions with Medicines

Although certain medicines must not be used with each other in all, in other cases two various medications may be made use of with each other also if an interaction might occur. In these cases, your medical professional might want to transform the dose, or various other safety measures may be required. When you are taking this medication, it is especially vital that your healthcare specialist recognize if you are taking any one of the medications listed below. The following communications have been picked on the basis of their potential importance and are not always all-inclusive.

Utilizing this medicine with any of the complying with medications is not suggested. Your doctor might determine not to treat you with this drug or alter some of the other medications you take.

  • Ketorolac

Using this medicine with any one of the adhering to medicines is usually not suggested, yet may be required in some cases. If both medicines are suggested with each other, your medical professional might change the dosage or exactly how often you use one or both of the medications.

  • Abciximab
  • Aceclofenac
  • Acemetacin
  • Amiloride
  • Amineptine
  • Amitriptyline
  • Amitriptylinoxide
  • Amoxapine
  • Amtolmetin Guacil
  • Anagrelide
  • Ardeparin
  • Aspirin
  • Balsalazide
  • Bemetizide
  • Bemiparin
  • Bendroflumethiazide
  • Benzthiazide
  • Betamethasone
  • Betrixaban
  • Bismuth Subsalicylate
  • Bromfenac
  • Budesonide
  • Bufexamac
  • Bumetanide
  • Cangrelor
  • Celecoxib
  • Certoparin
  • Chlorothiazide
  • Chlorthalidone
  • Choline Magnesium Trisalicylate
  • Choline Salicylate
  • Cilostazol
  • Citalopram
  • Clomipramine
  • Clonixin
  • Clopamide
  • Clopidogrel
  • Cortisone
  • Cyclopenthiazide
  • Cyclosporine
  • Cyclothiazide
  • Dalteparin
  • Danaparoid
  • Deflazacort
  • Desipramine
  • Desmopressin
  • Desvenlafaxine
  • Dexamethasone
  • Dexibuprofen
  • Dexketoprofen
  • Diazoxide
  • Dibenzepin
  • Diclofenac
  • Diflunisal
  • Digoxin
  • Dipyridamole
  • Dipyrone
  • Dothiepin
  • Doxepin
  • Droxicam
  • Duloxetine
  • Edoxaban
  • Emtricitabine
  • Enoxaparin
  • Eplerenone
  • Epoprostenol
  • Eptifibatide
  • Escitalopram
  • Ethacrynic Acid
  • Etodolac
  • Etofenamate
  • Etoricoxib
  • Etozolin
  • Felbinac
  • Fenoprofen
  • Fepradinol
  • Feprazone
  • Feverfew
  • Floctafenine
  • Flufenamic Acid
  • Fluocortolone
  • Fluoxetine
  • Flurbiprofen
  • Fluvoxamine
  • Furosemide
  • Ginkgo
  • Gossypol
  • Hydrochlorothiazide
  • Hydrocortisone
  • Hydroflumethiazide
  • Ibuprofen
  • Iloprost
  • Imipramine
  • Indapamide
  • Indomethacin
  • Inotersen
  • Ketoprofen
  • Levomilnacipran
  • Lithium
  • Lofepramine
  • Lornoxicam
  • Loxoprofen
  • Lumiracoxib
  • Magnesium Salicylate
  • Meadowsweet
  • Meclofenamate
  • Mefenamic Acid
  • Melitracen
  • Meloxicam
  • Melphalan
  • Mesalamine
  • Methotrexate
  • Methyclothiazide
  • Methylprednisolone
  • Metolazone
  • Milnacipran
  • Morniflumate
  • Nabumetone
  • Nadroparin
  • Naproxen
  • Nefazodone
  • Nepafenac
  • Niflumic Acid
  • Nimesulide
  • Nimesulide Beta Cyclodextrin
  • Nortriptyline
  • Olsalazine
  • Opipramol
  • Oxaprozin
  • Oxyphenbutazone
  • Paramethasone
  • Parecoxib
  • Parnaparin
  • Paroxetine
  • Pemetrexed
  • Pentosan Polysulfate Sodium
  • Pentoxifylline
  • Phenylbutazone
  • Phenyl Salicylate
  • Piketoprofen
  • Piretanide
  • Piroxicam
  • Polythiazide
  • Potassium Citrate
  • Prasugrel
  • Prednisolone
  • Prednisone
  • Proglumetacin
  • Propyphenazone
  • Proquazone
  • Protriptyline
  • Quinethazone
  • Reviparin
  • Rofecoxib
  • Salicylamide
  • Salicylic Acid
  • Salsalate
  • Selexipag
  • Sertraline
  • Sibutramine
  • Sodium Salicylate
  • Spironolactone
  • Sulfasalazine
  • Sulfinpyrazone
  • Sulindac
  • Tacrolimus
  • Tenofovir Alafenamide
  • Tenofovir Disoproxil Fumarate
  • Tenoxicam
  • Tianeptine
  • Tiaprofenic Acid
  • Ticagrelor
  • Ticlopidine
  • Tinzaparin
  • Tirofiban
  • Tolfenamic Acid
  • Tolmetin
  • Torsemide
  • Trazodone
  • Treprostinil
  • Triamterene
  • Trichlormethiazide
  • Trimipramine
  • Trolamine Salicylate
  • Valdecoxib
  • Venlafaxine
  • Vilazodone
  • Vorapaxar
  • Vortioxetine
  • Xipamide

Using this medicine with any of the complying with medications may create an increased threat of specific negative effects, however making use of both medicines might be the very best treatment for you. If both medicines are prescribed together, your doctor might change the dose or exactly how often you utilize one or both of the medicines.

  • Acebutolol
  • Acenocoumarol
  • Anisindione
  • Atenolol
  • Azilsartan
  • Azilsartan Medoxomil
  • Benazepril
  • Betaxolol
  • Bisoprolol
  • Candesartan
  • Captopril
  • Carteolol
  • Carvedilol
  • Celiprolol
  • Dicumarol
  • Enalapril
  • Enalaprilat
  • Eprosartan
  • Esmolol
  • Fosinopril
  • Irbesartan
  • Labetalol
  • Levobunolol
  • Lisinopril
  • Losartan
  • Metipranolol
  • Metoprolol
  • Moexipril
  • Nadolol
  • Nebivolol
  • Olmesartan
  • Oxprenolol
  • Penbutolol
  • Perindopril
  • Phenindione
  • Phenprocoumon
  • Pindolol
  • Probenecid
  • Propranolol
  • Quinapril
  • Ramipril
  • Sotalol
  • Spirapril
  • Tamarind
  • Telmisartan
  • Timolol
  • Trandolapril
  • Valsartan
  • Warfarin

Interactions with Food/Tobacco/Alcohol

Specific medications ought to not be used at or around the moment of consuming food or eating specific sorts of food considering that interactions may take place. Using alcohol or tobacco with specific medicines might likewise trigger communications to occur. Talk about with your healthcare professional using your medication with food, alcohol, or cigarette.

Other Medical Problems

The existence of various other clinical problems may affect using this medicine. See to it you inform your medical professional if you have any kind of various other medical problems, especially:

  • Blood vessel disease or
  • Diabetes-- Use with caution. May cause serious inflammation or ulcer, particularly on the hands or feet.
  • Inflammation, irritation, or infection of the skin-- Use of this medicine might create extreme inflammation if put on inflamed, inflamed, or contaminated area of the skin.
  • Influenza (flu) or
  • Varicella (poultry pox)-- Should not be utilized in kids and teenagers with the flu or hen pox. There is a risk of Reye's syndrome.
  • Kidney condition or
  • Liver disease-- Using this medicine for a long period of time over huge locations could cause undesirable effects.

This section was rewritten for readability and reviewed for meaning.

Side Effects of Zapzyt

In addition to its required impacts, a medicine may cause some unwanted results. Although not every one of these side effects might take place, if they do happen they might require medical focus.

Contact your doctor quickly if any of the following negative effects happen:

Much less common or unusual

  • Skin inflammation not present prior to use this medication (modest or extreme).

Incidence not known.

  • Difficult breathing.
  • dryness and peeling of skin.
  • fainting.
  • hives or itching.
  • inflammation of the skin.
  • swelling of the eyes, face, lips, or tongue.
  • rigidity in the throat.
  • abnormally cozy skin.

Get emergency aid right away if any one of the adhering to signs of overdose take place:.

Signs of overdose.

  • Confusion.
  • diarrhea.
  • lightheadedness.
  • quick or deep breathing.
  • frustration (serious or proceeding).
  • hearing loss.
  • faintness.
  • nausea or vomiting.
  • fast breathing.
  • ringing or humming in the ears (continuing).
  • severe sleepiness.
  • stomach pain.
  • throwing up.

Some side effects might happen that usually do not require clinical focus. These adverse effects might vanish throughout therapy as your body adjusts to the medicine. Additionally, your health care professional might be able to tell you about ways to prevent or decrease some of these negative effects. Talk to your health care specialist if any of the adhering to side effects proceed or are annoying or if you have any kind of inquiries regarding them:.

Much more common.

  • Skin inflammation absent prior to use this medicine (light).
  • stinging.

Opposite side effects not provided may additionally happen in some patients. If you observe any kind of other impacts, contact your medical care expert.

Call your medical professional for medical suggestions about negative effects. You might report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

  • Akurza.
  • Aliclen.
  • Avosil.
  • Betasal.
  • Compound W.
  • Corn Removing.
  • Dermarest Psoriasis.
  • DHS Sal.
  • Drytex.
  • Duofilm.
  • Duoplant.
  • Durasal.
  • Freezone.
  • Fung-O.
  • Gets-It Corn/Callus Remover.
  • Gordofilm.
  • Hydrisalic.
  • Ionil.
  • Ionil Plus.
  • Keralyt.
  • Keralyt Scalp.
  • Lupicare.
  • Mediplast.
  • Mg217 Sal-Acid.
  • Mosco Corn & Callus Remover.
  • Neutrogena.
  • Occlusal-HP.
  • Off-Ezy.
  • Oxy Balance.
  • P & S.
  • Palmer's Skin Success Acne Cleanser.
  • Propa pH.
  • Salac.
  • Sal-Acid Plaster.
  • Salactic Film.
  • Salacyn.
  • Salex.
  • Salitop.
  • Salkera.
  • Sal-Plant Gel.
  • Salvax.
  • Seba-Clear.
  • Stri-Dex.
  • Thera-Sal.
  • Therasoft Anti-Acne.
  • Tinamed.
  • Ti-Seb.
  • Virasal.
  • Wart-Off Maximum Strength.
  • Zapzyt.

In Canada.

  • Acnex.
  • Acnomel Acne Mask.
  • Clear Away Wart Removal System.
  • Compound W One-Step Wart Remover.
  • Compound W Plus.
  • Dr. Scholl's Clear Away One Step Plantar Wart Remover.
  • Dr. Scholl's Cushlin Ultra Slim Callus Removers.
  • Dr. Scholl's Cushlin Ultra Slim Corn Removers.
  • Duoforte 27.
  • Freezone - One Step Callus Remover Pad.
  • Freezone - One Step Corn Remover Pad.

Available Dosage Forms:.

  • Gel/Jelly.
  • Solution.
  • Soap.
  • Pad.
  • Liquid.
  • Spray.
  • Cream.
  • Ointment.
  • Foam.
  • Lotion.
  • Patch, Extended Release.
  • Bandage.
  • Shampoo.

Therapeutic Class: Keratolytic.

Pharmacologic Class: NSAID.

Chemical Class: Salicylate, Non-Aspirin.

This section was rewritten for readability and reviewed for meaning.

Proper use of Zapzyt

Use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than recommended on the label, unless otherwise directed by your doctor. To do so may increase the chance of absorption through the skin and the chance of salicylic acid poisoning.

This medicine is for use only on the skin. Do not get any of it in your eyes, nose, or mouth. Rinse it off with water right away if it does get on these areas.

Before using an OTC acne product for the first time, apply a small amount to one or two small affected areas of the skin for 3 days. If no discomfort occurs, follow the directions on the drug facts label of the product.

If your doctor has ordered an occlusive dressing (airtight covering, such as kitchen plastic wrap) to be applied over this medicine, make sure you know how to apply it. Since an occlusive dressing will increase the amount of medicine absorbed through your skin and the possibility of salicylic acid poisoning, use it only as directed. If you have any questions about this, check with your doctor.

Keep this medicine away from the eyes and other mucous membranes, such as the mouth and inside of the nose. If you should accidentally get some in your eyes or on other mucous membranes, immediately flush them with water for 15 minutes.

To use the cream, lotion, or ointment:

  • Apply enough medicine to cover the affected area, and rub in gently.

To use the gel:

  • Before using salicylic acid gel, apply wet packs to the affected areas for at least 5 minutes. If you have any questions about this, check with your doctor.
  • Apply enough gel to cover the affected areas, and rub in gently.

To use the pad:

  • Wipe the pad over the affected areas.
  • Do not rinse off medicine after treatment.

To use the plaster for warts, corns, or calluses:

  • This medicine comes with patient instructions. Read them carefully before using.
  • Do not use this medicine on irritated skin or on any area that is infected or reddened. Also, do not use this medicine if you are a diabetic or if you have poor blood circulation.
  • Do not use this medicine on warts with hair growing from them or on warts on the face, in or on the genital (sex) organs, or inside the nose or mouth. Also do not use on moles or birthmarks. To do so may cause severe irritation.
  • Wash the area to be treated and dry thoroughly. Warts may be soaked in warm water for 5 minutes before drying.
  • Cut the plaster to fit the wart, corn, or callus and apply.
  • For corns and calluses: Repeat every 48 hours as needed for up to 14 days, or as directed by your doctor, until the corn or callus is removed. Corns or calluses may be soaked in warm water for 5 minutes to help in their removal.
  • For warts: Depending on the product, either: Apply plaster and repeat every 48 hours as needed, or Apply plaster at bedtime, leave in place for at least 8 hours, remove plaster in the morning, and repeat every 24 hours as needed. Repeat for up to 12 weeks as needed, or as directed by your doctor, until wart is removed.
  • If discomfort gets worse during treatment or continues after treatment, or if the wart spreads, check with your doctor.

To use the shampoo:

  • Before applying this medicine, wet the hair and scalp with lukewarm water. Apply enough medicine to work up a lather and rub well into the scalp for 2 or 3 minutes, then rinse. Apply the medicine again and rinse thoroughly.

To use the soap:

  • Work up a lather with the soap, using hot water, and scrub the entire affected area with a washcloth or facial sponge or mitt.
  • If you are to use this soap in a foot bath, work up rich suds in hot water and soak the feet for 10 to 15 minutes. Then pat dry without rinsing.

To use the topical solution:

  • Wet a cotton ball or pad with the topical solution and wipe the affected areas.
  • Do not rinse off medicine after treatment.

To use the topical solution for warts, corns, or calluses:

  • This medicine comes with patient instructions. Read them carefully before using.
  • This medicine is flammable. Do not use it near heat or open flame or while smoking.
  • Do not use this medicine on irritated skin or on any area that is infected or reddened. Also, do not use this medicine if you are a diabetic or if you have poor blood circulation.
  • Do not use this medicine on warts with hair growing from them or on warts on the face, in or on the genital (sex) organs, or inside the nose or mouth. Also do not use on moles or birthmarks. To do so may cause severe irritation.
  • Avoid breathing in the vapors from the medicine.
  • Wash the area to be treated and dry thoroughly. Warts may be soaked in warm water for 5 minutes before drying.
  • Apply the medicine one drop at a time to completely cover each wart, corn, or callus. Let dry.
  • For warts—Repeat one or two times a day as needed for up to 12 weeks, or as directed by your doctor, until wart is removed.
  • For corns and calluses—Repeat one or two times a day as needed for up to 14 days, or as directed by your doctor, until the corn or callus is removed.
  • Corns and calluses may be soaked in warm water for 5 minutes to help in their removal.
  • If discomfort gets worse during treatment or continues after treatment, or if the wart spreads, check with your doctor.

Unless your hands are being treated, wash them immediately after applying this medicine to remove any medicine that may be on them.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For topical dosage form (cream):For corns and calluses: Adults—Use the 2 to 10% cream as needed. Use the 25 to 60% cream once every 3 to 5 days. Children 2 years of age and older—Use the 2 to 10% cream as needed. Use the 25 to 60% cream once every 3 to 5 days. Children younger than 2 years of age—Use is not recommended.
  • For topical dosage form (gel): For acne: Adults—Use the 0.5 to 5% gel once a day. Children 2 years of age and older—Use the 0.5 to 5% gel once a day. Children younger than 2 years of age—Use is not recommended. For psoriasis: Adults—Use the 5% gel once a day. Children 2 years of age and older—Use the 5% gel once a day. Children younger than 2 years of age—Use is not recommended. For common warts: Adults—Use the 5 to 26% gel one time a day. Children 2 years of age and older—Use the 5 to 26% gel one time a day. Children younger than 2 years of age—Use is not recommended.
  • For topical dosage form (lotion): For acne: Adults—Use the 1 to 2% lotion one to three times a day. Children 2 years of age and older—Use the 1 to 2% lotion one to three times a day Children younger than 2 years of age—Use is not recommended. For dandruff and antiseborrhic dermatitis of the scalp: Adults—Use the 1.8 to 2% lotion on the scalp one or two times a day. Children 2 years of age and older—Use the 1.8 to 2% lotion on the scalp one or two times a day. Children younger than 2 years of age—Use is not recommended.
  • For topical dosage form (ointment): For acne: Adults—Use the 3 to 6% ointment as needed. Children 2 years of age and older—Use the 3 to 6% ointment as needed. Children younger than 2 years of age—Use is not recommended. For psoriasis and seborrheic dermatitis: Adults—Use the 3 to 10% ointment as needed. Children 2 years of age and older—Use the 3 to 10% ointment as needed. Children younger than 2 years of age—Use is not recommended. For common warts: Adults—Use the 3 to 10% ointment as needed. Use the 25 to 60% ointment one time every 3 to 5 days. Children 2 years of age and older—Use the 3 to 10% ointment as needed. Use the 25 to 60% ointment one time every 3 to 5 days. Children younger than 2 years of age—Use is not recommended.
  • For pads dosage form: For acne: Adults—Use one to three times a day. Children 2 years of age and older—Use one to three times a day. Children younger than 2 years of age—Use is not recommended.
  • For plaster dosage form: For corns, calluses, common warts, or plantar warts: Adults—Use once a day or once every other day. Children 2 years of age and older—Use once a day or once every other day. Children younger than 2 years of age—Use is not recommended.
  • For shampoo dosage form: For dandruff or seborrheic dermatitis of the scalp: Adults—Use on the scalp one or two times a week. Children 2 years of age and older—Use on the scalp one or two times a week. Children younger than 2 years of age—Use is not recommended.
  • For soap dosage form: For acne: Adults—Use as needed. Children 2 years of age and older—Use as needed. Children younger than 2 years of age—Use is not recommended.
  • For topical solution dosage form: For acne: Adults—Use the 0.5 to 2% topical solution one to three times a day. Children 2 years of age and older—Use the 0.5 to 2% topical solution one to three times a day. Children younger than 2 years of age—Use is not recommended. For common warts and plantar warts: Adults—Use the 5 to 27% topical solution one or two times a day. Children 2 years of age and older—Use the 5 to 27% topical solution one or two times a day. Children younger than 2 years of age—Use is not recommended. For corns and calluses: Adults—Use the 12 to 27% topical solution one or two times a day. Children 2 years of age and older—Use the 12 to 27% topical solution one or two times a day. Children younger than 2 years of age—Use is not recommended.

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Frequently asked questions

  • Does duct tape really remove warts?

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
General medicine information Consumer-friendly language

Content is provided for education and is not medical advice. See our medical disclaimer.